Capixyl is a cosmetic active complex combining a biomimetic peptide (acetyl tetrapeptide-3) with red clover extract (rich in biochanin A), marketed to reduce hair loss and stimulate follicle activity by inhibiting 5-alpha-reductase and supporting the dermal papilla extracellular matrix. It is used in topical leave-on scalp and hair products.
| Reported effect | How often | Notes |
|---|---|---|
Scalp irritation or itching | Uncommon | Mild local irritation possible, often related to other formulation components rather than the active itself. |
Contact dermatitis / allergic reaction | Rare | Possible sensitization to peptide or botanical (red clover) components in susceptible individuals. |
Redness or transient stinging at application site | Rare | Usually mild and self-limiting. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.