Prenylflavonoids extracted from Maclura cochinchinensis leaves are plant-derived polyphenols studied for their antioxidant, anti-inflammatory, and tyrosinase-inhibiting (skin-brightening) properties. They are used in topical formulations to help reduce hyperpigmentation and counter oxidative stress.
| Reported effect | How often | Notes |
|---|---|---|
Mild skin irritation or redness | Rare | Possible transient irritation, more likely at higher concentrations or in sensitive skin. |
Allergic contact dermatitis | Very rare | Botanical polyphenols can rarely provoke sensitization in predisposed individuals. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.