2-Mercaptonicotinoyl Glycine is a thiol-containing amino acid derivative used in skincare for its antioxidant properties and reported ability to help regulate sebum production and reduce oxidized squalene, which is associated with oily skin and acne. It functions primarily as a treatment active rather than a base ingredient.
| Reported effect | How often | Notes |
|---|---|---|
| Mild skin irritation or redness | Uncommon | Possible at application site, generally transient. |
| Stinging or tingling sensation | Rare | Typically mild and short-lived, especially on sensitive skin. |
| Contact allergy / sensitization | Very rare | Thiol compounds can occasionally trigger allergic contact dermatitis. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.