Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme involved in cellular energy metabolism and redox reactions, and is studied in topical formulations for its potential roles in supporting skin cell function, repair, and protection against oxidative stress. As a precursor-related compound to niacinamide, it is being explored for anti-aging and barrier-supporting effects.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient irritation or redness | Uncommon | May occur at application site, generally resolves quickly. |
| Itching or stinging | Rare | Reported in sensitive individuals upon topical use. |
| Contact dermatitis / allergic reaction | Very rare | Hypersensitivity reactions are uncommon but possible. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.