Phenyl t-Butylnitrone (PBN) is a nitrone-based spin-trapping antioxidant used in skincare for its ability to neutralize free radicals and reduce oxidative stress in skin. It is investigated for protecting against UV- and pollution-induced damage.
| Reported effect | How often | Notes |
|---|---|---|
| Skin irritation or redness | Rare | Mild local irritation possible in sensitive individuals at higher concentrations. |
| Contact sensitization/allergic reaction | Very rare | Limited topical data; rare reports of allergic response. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.