SH-Oligopeptide-1 is a synthetic version of human epidermal growth factor (EGF) used in skincare to support cell proliferation, wound healing, and signs of skin repair and rejuvenation. It is typically incorporated into anti-aging and post-procedure formulations at low concentrations.
| Reported effect | How often | Notes |
|---|---|---|
| Mild irritation or redness | Uncommon | Transient, usually resolving after discontinuation or with reduced frequency of use. |
| Contact dermatitis or allergic sensitization | Rare | May occur in individuals sensitive to peptides or other formulation components. |
| Theoretical concern regarding cell proliferation in compromised skin | Very rare | Limited clinical data; caution sometimes advised in those with active skin malignancies, though evidence is inconclusive. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.