Sodium PCA (sodium pyrrolidone carboxylic acid) is the salt of pyroglutamic acid and a natural moisturizing factor (NMF) found in skin. It is a highly effective humectant that attracts and binds water to the stratum corneum, improving hydration and softness.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient stinging or irritation | Rare | More likely on compromised or broken skin; generally well tolerated. |
| Contact dermatitis / allergic sensitization | Very rare | Isolated reports; sodium PCA is considered low risk for sensitization. |
| Increased skin penetration of co-formulated ingredients | Uncommon | As a humectant it may enhance hydration and potentially the uptake of other agents. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.