Tetramethyl Acetyloctahydronaphthalenes (commonly known as Iso E Super) is a synthetic aroma chemical with a woody, ambergris-like scent used to add fragrance and act as a fixative in cosmetic and personal care products. It has no skincare benefit and serves purely as a scent component.
| Reported effect | How often | Notes |
|---|---|---|
| Allergic contact dermatitis | Uncommon | Can sensitize susceptible individuals; recognized as a fragrance allergen in patch-test studies. |
| Skin irritation | Uncommon | May cause redness or stinging, particularly in those with sensitive skin or at higher concentrations. |
| Cross-reactivity in fragrance-sensitive individuals | Rare | Reported in people with pre-existing fragrance allergies. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.