Vitis Vinifera (grape) seed extract is a polyphenol-rich botanical extract used in skincare for its antioxidant activity, helping to neutralize free radicals and protect skin from oxidative stress. It is valued for proanthocyanidins and resveratrol-related compounds that may support skin barrier and anti-aging benefits.
| Reported effect | How often | Notes |
|---|---|---|
| Mild skin irritation or stinging | Uncommon | Usually transient, more likely in sensitive skin or higher concentrations. |
| Allergic contact dermatitis | Rare | Botanical extracts can occasionally sensitize predisposed individuals. |
| Redness or erythema | Uncommon | Typically mild and resolves after discontinuation. |
| Contact urticaria | Very rare | Isolated hypersensitivity reactions reported with plant-derived ingredients. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
Peer-reviewed papers on this ingredient, via PubMed.