Xanthine is a purine-derived compound and the parent structure of methylxanthines (such as caffeine and theophylline) used in skincare for antioxidant, anti-inflammatory, and microcirculation-stimulating properties. It is often included in formulations targeting puffiness, dark circles, and cellulite.
| Reported effect | How often | Notes |
|---|---|---|
| Skin irritation or redness | Uncommon | Possible at higher concentrations, especially on sensitive skin. |
| Contact dermatitis | Rare | Allergic sensitization has been occasionally reported with methylxanthine derivatives. |
| Dryness or mild stinging | Rare | Typically transient and formulation-dependent. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.