Carica Papaya (papaya) extract contains the proteolytic enzyme papain along with vitamins and antioxidants, and is used in skincare for gentle enzymatic exfoliation and brightening. It helps break down surface keratin and dead skin cells, promoting smoother skin texture.
| Reported effect | How often | Notes |
|---|---|---|
| Skin irritation (redness, stinging, burning) | Common | Most likely with higher enzyme concentrations or on sensitive skin. |
| Contact dermatitis | Uncommon | May occur in individuals sensitive to papain or latex-related proteins. |
| Allergic reaction / hypersensitivity | Rare | Papain is a known potential allergen; cross-reactivity reported in latex-fruit syndrome. |
| Anaphylaxis or severe systemic allergic response | Very rare | Documented mainly with ingested or inhaled papain rather than topical use. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.