Desamido collagen is a hydrolyzed collagen derivative produced by deamidation, which improves water solubility and skin/hair affinity. It is used in cosmetics as a moisturizing and film-forming agent that helps reduce transepidermal water loss and improve surface smoothness.
| Reported effect | How often | Notes |
|---|---|---|
Mild transient skin irritation or redness | Rare | Generally well tolerated; minor irritation possible in sensitive individuals. |
Contact allergic reaction | Very rare | Hypersensitivity to collagen-derived peptides is uncommon but documented. |
Acne or follicular occlusion | Very rare | Film-forming behavior could theoretically contribute in very occlusive formulations. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.