Mahonia Aquifolium (Oregon grape) Flower/Leaf/Stem Extract is a plant-derived ingredient containing alkaloids such as berberine, valued in skincare for its antioxidant, anti-inflammatory, and antiproliferative properties. It has been studied for use in conditions like psoriasis and other inflammatory skin disorders.
| Reported effect | How often | Notes |
|---|---|---|
| Mild burning or stinging on application | Uncommon | Transient local irritation reported in some topical use studies. |
| Erythema (skin redness) | Uncommon | Localized redness at application site, usually mild and self-limiting. |
| Itching/pruritus | Uncommon | Occasionally reported with topical formulations. |
| Allergic contact dermatitis | Rare | Possible sensitization in predisposed individuals; patch testing advised. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.