Below is every ingredient in Cica + 2% Salicylic Acid Serum for Acne explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Salicylic acid is a lipid-soluble beta-hydroxy acid that exfoliates the skin surface and penetrates sebaceous pores to loosen and dissolve keratin and debris. It is widely used to treat acne, blackheads, and conditions involving thickened or scaly skin.
Glycine Soja (soybean) Seed Extract is a soy-derived ingredient rich in isoflavones, proteins, and fatty acids used in skincare for antioxidant, moisturizing, and skin-conditioning effects. It is also studied for brightening and anti-aging benefits attributed to its phytoestrogen and antioxidant content.
Houttuynia Cordata Extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and antimicrobial properties. It is often included to calm sensitive or acne-prone skin and reduce redness.
Scutellaria Baicalensis Root Extract is a plant-derived ingredient rich in flavonoids such as baicalin, baicalein, and wogonin, valued in skincare for its antioxidant, anti-inflammatory, and skin-soothing properties. It is commonly used to help calm irritation and protect skin against environmental oxidative stress.
Melia Azadirachta (neem) Leaf Extract is a plant-derived ingredient valued for its antioxidant, anti-inflammatory, and antimicrobial properties, often used in skincare for soothing and conditioning effects. It contains bioactive compounds such as nimbidin and flavonoids.
Rehmannia Chinensis Root Extract is derived from the root of the Rehmannia glutinosa plant and is used in skincare for its purported antioxidant, anti-inflammatory, and soothing properties. It contains compounds such as catalpol and iridoid glycosides that may help calm irritated skin.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Irritation or sensitivity | Very rare | Purified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water. |
| Transepidermal water loss aggravation in compromised skin | Rare | Evaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent. |
| Mild skin irritation | Uncommon | Possible at higher concentrations, particularly on sensitive or compromised skin. |
| Allergic contact dermatitis | Rare | Sensitization to glycol ethers is infrequently reported. |
| Enhanced irritation from co-formulated actives | Uncommon | By increasing penetration, it may intensify the effects or irritation potential of other ingredients. |
| Eye irritation | Rare | Can occur with accidental contact in concentrated form. |
| Enhanced penetration of co-formulated irritants | Uncommon | As a penetration enhancer it may increase absorption and irritation potential of other actives. |
| Mild transient stinging or irritation | Uncommon | More likely on broken or compromised skin or at high concentrations. |
| Redness or itching | Rare | Typically resolves after discontinuation. |
| Skin dryness and peeling | Common | Mild flaking or tightness, especially with frequent use or higher concentrations. |
| Stinging, burning, or irritation | Common | Transient sensation on application, often more pronounced on sensitive or compromised skin. |
| Erythema (redness) | Common | Temporary redness at the application site. |
| Contact dermatitis | Uncommon | Localized inflammation; can be irritant or, less often, allergic in nature. |
| Increased photosensitivity | Uncommon | Exfoliation may heighten sun sensitivity; sunscreen use is advised. |
| Salicylism (systemic toxicity) | Rare | Reported with extensive application over large body areas, high concentrations, or occlusion; symptoms include nausea, tinnitus, and dizziness. |
| Severe allergic reaction | Very rare | Hypersensitivity reactions such as significant swelling or hives. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Aqua Solvent / vehicle | Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery. |
| Ethoxydiglycol Solvent / penetration enhancer | Ethoxydiglycol (diethylene glycol monoethyl ether) is a glycol ether used in cosmetic formulations primarily as a solvent and viscosity reducer that helps dissolve active ingredients and improve their skin penetration. It is considered a formulation aid rather than a therapeutic active. |
| Propanediol Humectant/solvent | Propanediol is a plant-derived glycol used in skincare as a humectant, solvent, and penetration enhancer that improves moisturization and the spreadability of formulations. It also helps solubilize other ingredients and can boost the efficacy of certain actives. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Salicylic Acid Key active Beta-hydroxy acid (BHA) exfoliant / keratolytic | Salicylic acid is a lipid-soluble beta-hydroxy acid that exfoliates the skin surface and penetrates sebaceous pores to loosen and dissolve keratin and debris. It is widely used to treat acne, blackheads, and conditions involving thickened or scaly skin. |
| Glycine Soja Seed Extract Key active Antioxidant/conditioning | Glycine Soja (soybean) Seed Extract is a soy-derived ingredient rich in isoflavones, proteins, and fatty acids used in skincare for antioxidant, moisturizing, and skin-conditioning effects. It is also studied for brightening and anti-aging benefits attributed to its phytoestrogen and antioxidant content. |
| Houttuynia Cordata Extract Key active Soothing antioxidant | Houttuynia Cordata Extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and antimicrobial properties. It is often included to calm sensitive or acne-prone skin and reduce redness. |
| Scutellaria Baicalensis Root Extract Key active Antioxidant / soothing botanical | Scutellaria Baicalensis Root Extract is a plant-derived ingredient rich in flavonoids such as baicalin, baicalein, and wogonin, valued in skincare for its antioxidant, anti-inflammatory, and skin-soothing properties. It is commonly used to help calm irritation and protect skin against environmental oxidative stress. |
| Melia Azadirachta Leaf Extract Key active Soothing/antimicrobial botanical extract | Melia Azadirachta (neem) Leaf Extract is a plant-derived ingredient valued for its antioxidant, anti-inflammatory, and antimicrobial properties, often used in skincare for soothing and conditioning effects. It contains bioactive compounds such as nimbidin and flavonoids. |
| Rehmannia Chinensis Root Extract Key active Soothing/antioxidant botanical extract | Rehmannia Chinensis Root Extract is derived from the root of the Rehmannia glutinosa plant and is used in skincare for its purported antioxidant, anti-inflammatory, and soothing properties. It contains compounds such as catalpol and iridoid glycosides that may help calm irritated skin. |
| Salix Alba Bark Extract Key active Natural exfoliant / anti-inflammatory | Salix Alba (White Willow) Bark Extract is a botanical source of salicin, which can be converted to salicylic acid, offering mild exfoliating, anti-inflammatory, and astringent properties. It is commonly used in formulations targeting acne-prone, oily, or congested skin as a gentler alternative to synthetic salicylic acid. |
| Phellodendron Amurense Bark Extract Key active Soothing / anti-inflammatory botanical | Phellodendron Amurense Bark Extract is a plant-derived extract rich in berberine and other alkaloids, used in skincare for its anti-inflammatory, antioxidant, and antimicrobial properties. It is commonly included to calm irritation, balance sebum, and support acne-prone or sensitive skin. |
| Lactobacillus/Pear Juice Ferment Filtrate Skin conditioning / fermented humectant | Lactobacillus/Pear Juice Ferment Filtrate is the filtrate produced by fermenting pear juice with Lactobacillus, yielding a mix of organic acids, peptides, and metabolites used as a skin-conditioning and hydrating agent. It is valued for mild humectant, antioxidant, and skin-barrier-supporting properties in cosmetic formulations. |
| Centella Asiatica Extract Key active Soothing/antioxidant active | Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations. |
| Zinc PCA Key active Sebum-regulating, antimicrobial | Zinc PCA is the zinc salt of pyrrolidone carboxylic acid used in skincare to help control excess sebum, support antimicrobial activity, and provide mild hydration. It is commonly included in products targeting oily and acne-prone skin. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Laminaria Digitata Extract Conditioning/antioxidant | Laminaria Digitata Extract is derived from brown seaweed and is used in skincare for its mineral, polysaccharide, and antioxidant content, providing skin-conditioning, hydrating, and soothing benefits. It is commonly included for its purported moisturizing and protective properties. |
| Hydrogenated Lecithin Emollient / Emulsifier | Hydrogenated lecithin is a phospholipid derived from lecithin through hydrogenation, used in skincare as an emulsifier, emollient, and skin-conditioning agent. It also helps stabilize formulations and form liposomes that can aid delivery of other ingredients. |
| Cetyl-PG Hydroxyethyl Palmitamide Skin-conditioning emollient / pseudo-ceramide | Cetyl-PG Hydroxyethyl Palmitamide is a synthetic pseudo-ceramide used to mimic natural skin ceramides, helping to support the skin barrier and reduce transepidermal water loss. It functions as an emollient and moisturizing agent commonly found in barrier-repair and dry-skin formulations. |
| Ceramide 1 Skin barrier lipid / moisturizer | Ceramide 1 (Ceramide EOP) is a naturally occurring epidermal lipid used in skincare to help restore and reinforce the skin's barrier and reduce transepidermal water loss. It is commonly combined with other ceramides, cholesterol, and fatty acids to mimic the skin's natural lipid matrix. |
| Ceramide 2 Skin-barrier lipid / moisturizer | Ceramide 2 (Ceramide NS) is a naturally occurring sphingolipid used in skincare to help restore and reinforce the skin's lipid barrier, reducing transepidermal water loss and improving hydration. It is generally well tolerated and biocompatible with the skin's own ceramides. |
| Ceramide 3 Skin barrier replenisher / emollient | Ceramide 3 (also called Ceramide NP) is a lipid naturally found in the skin's stratum corneum that helps restore and maintain the skin barrier and reduce transepidermal water loss. It is widely used in moisturizers and barrier-repair formulations to improve hydration and skin integrity. |
| Ceramide 4 Skin-barrier lipid / emollient | Ceramide 4 (Ceramide AP) is a naturally occurring skin lipid used in formulations to help restore and reinforce the skin barrier and reduce transepidermal water loss. It supports the stratum corneum's lipid matrix, improving hydration and skin resilience. |
| Ceramide 6 Skin barrier repair / moisturizing lipid | Ceramide 6 (Ceramide AP) is a naturally occurring lipid that helps restore and maintain the skin's barrier function and reduce transepidermal water loss. It is commonly included in moisturizers and barrier-repair formulations to improve hydration and skin integrity. |
| Cholesterol Skin barrier lipid / emollient | Cholesterol is a naturally occurring lipid found in the skin's stratum corneum that, alongside ceramides and fatty acids, helps maintain the skin barrier and prevent transepidermal water loss. In skincare formulations it functions as an emollient and barrier-repair agent that improves hydration and skin resilience. |
| 1,2-Hexanediol Humectant / preservative booster | 1,2-Hexanediol is a synthetic diol used in skincare as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, often allowing reduced or preservative-free systems. It helps maintain product stability while contributing mild moisturizing properties. |
| Gluconolactone Key active Polyhydroxy acid (PHA) exfoliant/humectant | Gluconolactone is a polyhydroxy acid that gently exfoliates the skin surface, provides antioxidant and humectant benefits, and is often considered milder than alpha hydroxy acids. It is well tolerated, including by sensitive skin, due to its larger molecular size and slower penetration. |
| Opuntia Ficus-Indica Stem Water Hydrating/soothing humectant | Opuntia Ficus-Indica (prickly pear) Stem Water is a botanical-derived water rich in polysaccharides and minerals, used to provide hydration and skin-soothing properties in cosmetic formulations. It functions primarily as a moisturizing and conditioning base ingredient rather than a high-potency treatment active. |
| Hamamelis Virginiana Extract Key active Astringent/antioxidant | Hamamelis Virginiana (witch hazel) extract is derived from the leaves, bark, and twigs of the witch hazel plant and is valued for its tannin content, providing astringent, anti-inflammatory, and antioxidant properties. It is commonly used in toners and after-shave products to tighten skin and reduce minor irritation. |
| Benzoic Acid Preservative | Benzoic acid is an organic acid used primarily as an antimicrobial preservative in cosmetic and skincare formulations, most effective in acidic products (pH below ~5). It helps inhibit the growth of bacteria, yeast, and mold to extend product shelf life. |
| Artemisia Vulgaris Extract Key active Soothing/antioxidant botanical | Artemisia Vulgaris (mugwort) Extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and skin-soothing properties, often featured in products targeting sensitive or irritated skin. It contains flavonoids and polyphenols thought to support skin barrier comfort. |
| Xanthan Gum Thickener/stabilizer | Xanthan gum is a polysaccharide produced by bacterial fermentation, used in skincare as a thickening, gelling, and emulsion-stabilizing agent. It improves product texture and suspension of ingredients without contributing active treatment effects. |
| Hydroxyethylcellulose Thickener/viscosity modifier | Hydroxyethylcellulose is a non-ionic, water-soluble cellulose derivative used to thicken, stabilize, and adjust the texture of aqueous cosmetic formulations. It functions as a gelling and film-forming agent rather than providing a direct biological skin benefit. |
| C18-22 Hydroxyalkyl Hydroxypropyl Guar Conditioning agent / rheology modifier | C18-22 Hydroxyalkyl Hydroxypropyl Guar is a modified guar gum derivative used in skincare and haircare to thicken formulations, stabilize emulsions, and impart a smooth, conditioned feel to skin and hair. It functions as a non-active formulation aid rather than a therapeutic active. |
| Allantoin Key active Soothing/skin-conditioning agent | Allantoin is a naturally derived or synthetically produced compound used in skincare for its soothing, moisturizing, and keratolytic (skin-softening) properties. It promotes cell proliferation and helps calm irritation, commonly appearing in creams, lotions, and after-sun products. |
| Sodium Hydroxide pH adjuster | Sodium hydroxide (lye) is a strong alkaline compound used in small amounts to adjust and stabilize the pH of cosmetic formulations. At regulated low concentrations in finished products it is considered safe, though it is corrosive in concentrated form. |
| Sodium Gluconate Chelating agent / skin-conditioning | Sodium gluconate is the sodium salt of gluconic acid used in skincare primarily as a chelating agent to bind metal ions and stabilize formulations, with secondary humectant and skin-conditioning properties. It is generally considered a base/formulation ingredient rather than an active treatment. |
| Disodium EDTA Chelating agent | Disodium EDTA is a chelating agent used in cosmetics to bind metal ions, improving product stability, preventing rancidity, and enhancing the efficacy of preservatives. It is a formulation/base ingredient rather than a treatment active. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Citric Acid pH adjuster / AHA exfoliant | Citric acid is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formulation pH and as a chelating agent, and at higher concentrations as a mild chemical exfoliant. It can promote surface cell turnover and is sometimes included in antioxidant or brightening products. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.