Below is every ingredient in Epifager Regale explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Bellis Perennis (Daisy) Flower Extract is a botanical extract used in skincare for its mild skin-brightening and tone-evening properties, attributed to polyphenols and saponins that may modestly inhibit melanin production. It is also valued as a skin-conditioning and antioxidant agent in cosmetic formulations.
Licorice root extract is a botanical ingredient valued in skincare for its skin-brightening and soothing properties, primarily attributed to compounds such as glabridin and liquiritin. It is used to help reduce hyperpigmentation, calm inflammation, and provide antioxidant protection.
Aspergillus Ferment is a bioactive ingredient produced by fermenting substrates with Aspergillus fungi, yielding a mixture of enzymes, peptides, polysaccharides, and amino acids used in skincare for hydrating, antioxidant, and skin-conditioning effects. It is often included for its purported brightening and barrier-supporting properties.
Phyllanthus Emblica (Indian gooseberry/Amla) fruit extract is a polyphenol-rich botanical used in skincare for its antioxidant and tyrosinase-inhibiting properties, often included to help brighten skin tone and reduce oxidative stress. It is also valued for its stability and chelating activity in formulations.
Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier.
Lepidium Sativum (garden cress) Sprout Extract is a botanical ingredient rich in sulforaphane, vitamins, and other phytochemicals, used in skincare for its antioxidant and cytoprotective properties. It is studied for supporting skin barrier function and modulating oxidative stress and inflammation.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Irritation or sensitivity | Very rare | Purified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water. |
| Transepidermal water loss aggravation in compromised skin | Rare | Evaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent. |
| Mild skin irritation or transient redness | Uncommon | May occur in sensitive skin, generally mild and self-limiting |
| Allergic contact dermatitis | Rare | Plant belongs to the Asteraceae (Compositae) family; cross-reactivity possible in individuals sensitized to related plants such as ragweed, chamomile, or arnica |
| Itching or stinging on application | Rare | Typically associated with compromised skin barrier or higher extract concentrations |
| Mild contact irritation | Rare | Occasional redness or stinging, usually in sensitive or compromised skin. |
| Comedogenicity / clogged pores | Rare | Generally low comedogenic potential, but acne-prone individuals may occasionally react. |
| Skin irritation or mild stinging | Rare | Generally well tolerated; transient irritation occasionally reported, often related to formulation rather than the ingredient itself. |
| Comedogenicity (pore clogging) | Uncommon | Has a low-to-moderate comedogenic potential in predisposed individuals at higher concentrations. |
| Mild skin irritation | Uncommon | Transient redness or stinging, more likely on compromised or sensitive skin. |
| Contact urticaria | Very rare | Isolated case reports of immediate-type reactions. |
| Comedogenicity / pore clogging | Uncommon | May contribute to clogged pores in acne-prone individuals depending on concentration and formulation. |
| Mild skin irritation or redness | Uncommon | Generally well tolerated; transient irritation can occur, especially on sensitive skin or at high concentrations. |
| Hypersensitivity reaction in mold-allergic individuals | Very rare | Theoretical risk given fungal origin; documented data are limited. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Aqua Solvent / vehicle | Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery. |
| Bellis Perennis (Daisy) Flower Extract Key active Skin brightening/conditioning agent | Bellis Perennis (Daisy) Flower Extract is a botanical extract used in skincare for its mild skin-brightening and tone-evening properties, attributed to polyphenols and saponins that may modestly inhibit melanin production. It is also valued as a skin-conditioning and antioxidant agent in cosmetic formulations. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Glycerol Stearate Emulsifier/emollient | Glyceryl stearate (glycerol stearate) is a glycerin-derived fatty acid ester widely used in skincare as a non-ionic emulsifier and emollient to stabilize oil-in-water formulations and improve skin feel. It also helps soften skin and reduce moisture loss by reinforcing the skin barrier. |
| PEG-100 Stearate Emulsifier/surfactant | PEG-100 Stearate is a polyethylene glycol ester of stearic acid used as a nonionic surfactant and emulsifier to stabilize oil-in-water formulations and improve skin feel. It functions as a formulation base ingredient rather than a therapeutic active. |
| Stearic Acid Emulsifier / thickener | Stearic acid is a saturated long-chain fatty acid widely used in cosmetics as an emulsifier, thickening agent, and emollient to stabilize creams and lotions. It is generally considered a base/formulation ingredient rather than a therapeutic active. |
| Glycyrrhiza Glabra (Licorice) Root Extract Key active Brightening / anti-inflammatory antioxidant | Licorice root extract is a botanical ingredient valued in skincare for its skin-brightening and soothing properties, primarily attributed to compounds such as glabridin and liquiritin. It is used to help reduce hyperpigmentation, calm inflammation, and provide antioxidant protection. |
| Aspergillus Ferment Key active Fermented extract / skin conditioning | Aspergillus Ferment is a bioactive ingredient produced by fermenting substrates with Aspergillus fungi, yielding a mixture of enzymes, peptides, polysaccharides, and amino acids used in skincare for hydrating, antioxidant, and skin-conditioning effects. It is often included for its purported brightening and barrier-supporting properties. |
| Ethoxydiglycol Solvent / penetration enhancer | Ethoxydiglycol (diethylene glycol monoethyl ether) is a glycol ether used in cosmetic formulations primarily as a solvent and viscosity reducer that helps dissolve active ingredients and improve their skin penetration. It is considered a formulation aid rather than a therapeutic active. |
| Myristyl Myristate Emollient / thickener | Myristyl myristate is a waxy ester of myristyl alcohol and myristic acid used in cosmetics as an emollient, thickening agent, and opacifier. It improves skin feel, spreadability, and texture in creams, lotions, and color cosmetics. |
| Cyclomethicone Emollient/silicone solvent | Cyclomethicone is a volatile cyclic silicone used in skincare and cosmetics to impart a smooth, silky feel and aid spreadability before evaporating without residue. It functions as a carrier and emollient rather than an active treatment ingredient. |
| Phyllanthus Emblica Fruit Extract Key active Antioxidant / skin-brightening | Phyllanthus Emblica (Indian gooseberry/Amla) fruit extract is a polyphenol-rich botanical used in skincare for its antioxidant and tyrosinase-inhibiting properties, often included to help brighten skin tone and reduce oxidative stress. It is also valued for its stability and chelating activity in formulations. |
| Saccharide Isomerate Humectant / moisturizer | Saccharide Isomerate is a plant-derived carbohydrate complex that binds to the skin's keratin to provide long-lasting hydration and improve moisture retention. It is structurally similar to carbohydrates naturally found in the skin's upper layers. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Bismuth Oxychloride Pigment/colorant | Bismuth oxychloride is an inorganic compound used in cosmetics, particularly mineral makeup and pressed powders, to impart a pearlescent, shimmering finish and improve adhesion and slip. It functions as a colorant and opacifying agent rather than a therapeutic active. |
| Tocopheryl Acetate Key active Antioxidant | Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier. |
| Lepidium Sativum Sprout Extract Key active Antioxidant / skin-conditioning active | Lepidium Sativum (garden cress) Sprout Extract is a botanical ingredient rich in sulforaphane, vitamins, and other phytochemicals, used in skincare for its antioxidant and cytoprotective properties. It is studied for supporting skin barrier function and modulating oxidative stress and inflammation. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Lecithin Emollient / Emulsifier | Lecithin is a naturally occurring phospholipid (commonly derived from soybean or egg) used in skincare as an emulsifier, emollient, and penetration enhancer. It helps stabilize oil-and-water formulations and supports the skin barrier by mimicking natural lipids. |
| Arbutin Key active Skin-brightening agent | Arbutin is a naturally derived hydroquinone glycoside used to reduce hyperpigmentation by inhibiting tyrosinase, the enzyme involved in melanin synthesis. It is commonly used to fade dark spots, melasma, and uneven skin tone. |
| Linolenic Acid Key active Skin-conditioning / barrier-repair fatty acid | Linolenic acid is an omega-3 polyunsaturated essential fatty acid used in skincare to support the skin's lipid barrier, reduce transepidermal water loss, and provide emollient and soothing benefits. It is also studied for mild anti-inflammatory and comedolytic effects. |
| Linoleic Acid Key active Skin-barrier lipid / emollient | Linoleic acid is an essential omega-6 polyunsaturated fatty acid and a key component of skin ceramides that helps maintain the epidermal barrier and reduce transepidermal water loss. It is also studied for normalizing sebum composition and reducing comedone formation in acne-prone skin. |
| Ascorbyl Palmitate Key active Antioxidant / Vitamin C derivative | Ascorbyl palmitate is a lipid-soluble, more stable ester of vitamin C (ascorbic acid) used as an antioxidant in skincare formulations. It can help protect formulas from oxidation and may offer some skin antioxidant benefits, though its conversion to active ascorbic acid in skin is limited. |
| Glutathione Key active Antioxidant / skin-brightening agent | Glutathione is a tripeptide antioxidant used in skincare for its melanin-modulating and antioxidant properties, often promoted to reduce hyperpigmentation and even skin tone. Topical efficacy data is limited and variable, with stronger systemic effects associated with oral or intravenous routes. |
| Alcohol Solvent / penetration enhancer | Alcohol (typically ethanol or denatured alcohol) is used in skincare as a solvent, antimicrobial agent, and to improve product spreadability and rapid drying. It also enhances penetration of other ingredients and gives a lightweight feel to formulations. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.