Fixderma · 🇮🇳 India

Face 21 Cream

10 ingredients
What's in it

Below is every ingredient in Face 21 Cream explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.

Suitability at a glance — for Indian skin

🍄 Fungal-acne safe
No known Malassezia triggers detected
Pore-clogging risk: Low
Highest comedogenic rating 1/5 — matters for oily, acne-prone skin
Fragrance-free
No fragrance or EU-declared allergens

Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.

Your questions, answered from the ingredient list

Is Face 21 Cream fungal-acne safe?
Based on its listed ingredients, no known Malassezia (fungal-acne) triggers were detected in Face 21 Cream.
Does Face 21 Cream contain fragrance?
No fragrance ingredients or EU-declared allergens were detected in the listed ingredients of Face 21 Cream.
Will Face 21 Cream clog pores?
The highest comedogenic rating among its listed ingredients is 1/5 (low). Comedogenicity matters most for oily, acne-prone skin in humid Indian weather; it is a property of ingredients in lab tests, not a guarantee either way.
Is Face 21 Cream safe to use in pregnancy?
None of its listed ingredients are flagged for pregnancy caution in our reference data — but always confirm your full routine with your own doctor.

Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.

Key actives

Octocrylene
UV filter

Octocrylene is an organic (chemical) sunscreen agent that absorbs UVB and short UVA radiation, and is also used to stabilize and solubilize other UV filters such as avobenzone. It is commonly incorporated into sunscreens and daily-care products with SPF.

Niacinamide
Cell-communicating / barrier-repair active

Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.

Titanium Dioxide
UV filter / mineral sunscreen

Titanium dioxide is an inorganic mineral compound used primarily as a physical (mineral) sunscreen agent that reflects and scatters UV radiation, and also serves as a white pigment and opacifier in cosmetic formulations. It is broadly photostable and considered gentle, making it common in products for sensitive and pediatric skin.

Side effects reported in research

Aggregated from the active ingredients in this product.

Reported effectHow oftenNotes
Irritation or stingingVery rarePure water is generally inert; rare reactions are typically attributed to impurities or other formula components rather than water itself.
Transient skin barrier disruption with frequent contactRareExcessive exposure (e.g., repeated wetting) may temporarily affect the skin barrier, but this is uncommon in cosmetic use.
Skin irritationRareGenerally well tolerated; mild irritation reported infrequently in sensitive individuals.
Allergic contact dermatitisVery rareIsolated case reports; the ester is considered a low sensitizer.
Comedogenicity (clogged pores)RareConsidered low to non-comedogenic, but possible in acne-prone skin depending on formulation.
Contact dermatitis / skin irritationUncommonLocalized redness, itching, or stinging on application.
Photoallergic contact dermatitisRareReported particularly in adults, sometimes linked to prior ketoprofen sensitization.
Systemic absorptionCommonDetectable in blood after use; clinical significance unclear and not equated with harm.
Benzophenone formation over timeUncommonDegradation can yield trace benzophenone; relevance to skin health under study.
Mild transient flushing or rednessUncommonMore likely at higher concentrations or in sensitive skin; usually subsides quickly.
Tingling, stinging, or burning sensationUncommonOften associated with higher percentages or compromised barrier.
Contact irritation or itchingRareGenerally dose-dependent and resolves with discontinuation.
Comedogenicity (pore-clogging)UncommonMay contribute to clogged pores or breakouts in acne-prone or oily skin, though shea is generally low on the comedogenic scale.
Skin irritation or rednessRareOccasional mild irritation, often related to impurities in unrefined products or individual sensitivity.

Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.

Full ingredient breakdown

IngredientWhat it does
Water (Aqua)
Solvent / vehicle
Water is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble ingredients and forms the continuous phase of emulsions. It hydrates the skin temporarily but does not act as a treatment active.
Isononyl Isononanoate
Emollient/skin-conditioning agent
Isononyl Isononanoate is a synthetic ester emollient used in cosmetics to impart a light, silky, non-greasy skin feel and to aid the spreadability of formulations. It functions as a base/texture ingredient rather than a treatment active.
Octocrylene Key active
UV filter
Octocrylene is an organic (chemical) sunscreen agent that absorbs UVB and short UVA radiation, and is also used to stabilize and solubilize other UV filters such as avobenzone. It is commonly incorporated into sunscreens and daily-care products with SPF.
Niacinamide Key active
Cell-communicating / barrier-repair active
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Butyrospermum Parkii (Shea) Butter
Emollient / occlusive moisturizer
Butyrospermum Parkii (Shea) Butter is a plant-derived fat extracted from the nuts of the African shea tree, rich in triglycerides and unsaponifiables. It is widely used in skincare to soften, smooth, and condition the skin while forming an occlusive barrier that reduces water loss.
Titanium Dioxide Key active
UV filter / mineral sunscreen
Titanium dioxide is an inorganic mineral compound used primarily as a physical (mineral) sunscreen agent that reflects and scatters UV radiation, and also serves as a white pigment and opacifier in cosmetic formulations. It is broadly photostable and considered gentle, making it common in products for sensitive and pediatric skin.
Xylitylglucoside
Humectant / moisturizer
Xylitylglucoside is a sugar-derived humectant, typically used in combination with anhydroxylitol and xylitol, that helps attract and retain water in the skin and supports the skin barrier. It is valued for its skin-hydrating and moisturizing properties in cosmetic formulations.
Anhydroxylitol
Humectant / moisturizing agent
Anhydroxylitol is a sugar-derived (xylitol) humectant used in skincare to attract and retain water, helping to maintain skin hydration and barrier function. It is often combined with xylitol and xylitylglucoside to enhance the skin's natural moisturizing factors.
Xylitol
Humectant / moisturizer
Xylitol is a sugar alcohol used in topical formulations as a humectant that helps attract and retain moisture in the skin, and it may support the skin's microbiome and barrier function. It is generally well tolerated and considered safe for topical use.
Cetearyl
Emulsifier / emollient
Cetearyl (cetearyl alcohol) is a fatty alcohol blend of cetyl and stearyl alcohols used to emulsify, stabilize, and thicken creams and lotions while imparting a smooth, conditioning feel. It functions as a base/formulation ingredient rather than a therapeutic active.

Key active = does the main work. Ingredient explanations are drawn from public databases & literature.

From published literature

Peer-reviewed papers on the active ingredients in this product, via PubMed.

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