Acetylarginyltryptophyl Diphenylglycine is a synthetic signal peptide used in cosmetic formulations, marketed to support skin firmness and reduce visible signs of aging by modulating extracellular matrix proteins. It is typically incorporated at low concentrations in serums and creams.
| Reported effect | How often | Notes |
|---|---|---|
Mild transient redness | Rare | Localized irritation possible at application site, usually self-resolving. |
Contact irritation or stinging | Rare | More likely in sensitive skin or when combined with other actives. |
Allergic contact dermatitis | Very rare | Hypersensitivity reactions are uncommon for synthetic peptides but theoretically possible. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.