Polygonum Multiflorum (Fo-Ti) root extract is a traditional botanical rich in stilbenes (e.g., resveratrol derivatives), anthraquinones, and polyphenols, used in skincare for its antioxidant and purported hair- and scalp-conditioning properties. In cosmetic formulations it is valued for free-radical scavenging and potential melanin-modulating effects.
| Reported effect | How often | Notes |
|---|---|---|
Allergic contact dermatitis | Uncommon | Localized redness, itching, or irritation in sensitized individuals applying topical preparations. |
Skin irritation | Uncommon | Mild stinging or erythema, more likely at higher concentrations or in sensitive skin. |
Photosensitivity | Rare | Anthraquinone constituents may theoretically increase sun sensitivity, though topical reports are limited. |
Hepatotoxicity | Rare | Well-documented with oral ingestion; not associated with topical cosmetic use but noted for context. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.