Below is every ingredient in Dermina Niacinamide Serum Powered With Allantoin And Cica Extracts explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Zinc Pyrrolidone Carboxylic Acid (Zinc PCA) is a zinc salt of pyrrolidone carboxylic acid used in skincare for its sebum-regulating, antimicrobial, and mild astringent properties. It is commonly included in formulations targeting oily, acne-prone, or seborrheic skin, and also provides some humectant activity.
Allantoin is a naturally derived or synthetically produced compound used in skincare for its soothing, moisturizing, and keratolytic (skin-softening) properties. It promotes cell proliferation and helps calm irritation, commonly appearing in creams, lotions, and after-sun products.
Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations.
Glycine Soja (soybean) Seed Extract is a soy-derived ingredient rich in isoflavones, proteins, and fatty acids used in skincare for antioxidant, moisturizing, and skin-conditioning effects. It is also studied for brightening and anti-aging benefits attributed to its phytoestrogen and antioxidant content.
Houttuynia Cordata Extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and antimicrobial properties. It is often included to calm sensitive or acne-prone skin and reduce redness.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Irritation or sensitivity | Very rare | Purified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water. |
| Transepidermal water loss aggravation in compromised skin | Rare | Evaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent. |
| Mild transient flushing or redness | Uncommon | More likely at higher concentrations or in sensitive skin; usually subsides quickly. |
| Tingling, stinging, or burning sensation | Uncommon | Often associated with higher percentages or compromised barrier. |
| Contact irritation or itching | Rare | Generally dose-dependent and resolves with discontinuation. |
| Allergic contact dermatitis | Very rare | Documented in isolated case reports; true sensitization is unusual. |
| Mild skin irritation | Uncommon | Transient stinging or redness, more likely at higher concentrations or on compromised skin. |
| Skin dryness | Uncommon | Its solvent action may contribute to dryness with repeated use in some individuals. |
| Eye irritation | Uncommon | Can cause irritation on direct ocular contact, relevant in eye-area products. |
| Systemic toxicity | Very rare | Of theoretical concern with large-scale ingestion or extreme exposure; not associated with normal topical cosmetic use. |
| Mild transient stinging or irritation | Uncommon | More likely on compromised or sensitive skin, or at higher concentrations. |
| Contact dermatitis / allergic sensitization | Rare | Reported infrequently; glycols are generally considered low sensitizers. |
| Enhanced irritation from co-formulated actives | Uncommon | As a penetration enhancer it may increase delivery and thus irritation potential of other ingredients. |
| Transient skin tightness or dryness on evaporation | Uncommon | Mineral residue can leave skin feeling tight if not followed by a moisturizer. |
| Mild irritation or stinging on compromised skin | Rare | Possible on broken or highly sensitive skin due to mineral content. |
| Allergic contact reaction | Very rare | Reactions are generally attributed to other formulation components rather than the water itself. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Aqua Solvent / vehicle | Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Diethylene Glycol Monoethyl Ether Solvent / penetration enhancer | Diethylene glycol monoethyl ether (ethoxydiglycol) is a versatile solvent and penetration enhancer used in cosmetic and topical formulations to dissolve active ingredients and improve their absorption into the skin. It also functions as a viscosity reducer and coupling agent in mixed-phase products. |
| Methyl Propanediol Solvent / penetration enhancer | Methyl propanediol (methylpropanediol) is a small glycol used as a humectant and solvent in cosmetic formulations. It helps dissolve other ingredients, improves spreadability, and can enhance the skin penetration of active compounds. |
| Thermal Water Soothing/mineralizing agent | Thermal water is mineral-rich spring water (containing elements such as selenium, silica, zinc, and various salts) used in skincare to hydrate, calm, and reduce irritation. It is typically used as a base or supportive ingredient rather than a treatment active. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Ethylhexyl Glycerin Preservative booster / skin-conditioning agent | Ethylhexyl glycerin is a multifunctional ingredient used primarily as a preservative-enhancer and humectant in cosmetic formulations. It also acts as a deodorizing agent by inhibiting odor-causing bacteria and improves the skin-feel of products. |
| Zinc Pyrrolidone Carboxylic Acid Key active Sebum-regulating / antimicrobial | Zinc Pyrrolidone Carboxylic Acid (Zinc PCA) is a zinc salt of pyrrolidone carboxylic acid used in skincare for its sebum-regulating, antimicrobial, and mild astringent properties. It is commonly included in formulations targeting oily, acne-prone, or seborrheic skin, and also provides some humectant activity. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Allantoin Key active Soothing/skin-conditioning agent | Allantoin is a naturally derived or synthetically produced compound used in skincare for its soothing, moisturizing, and keratolytic (skin-softening) properties. It promotes cell proliferation and helps calm irritation, commonly appearing in creams, lotions, and after-sun products. |
| Centella Asiatica Extract Key active Soothing/antioxidant active | Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations. |
| Fragrance Fragrance/masking agent | Fragrance refers to a blend of natural or synthetic aromatic compounds added to skincare products to impart a pleasant scent or mask the odor of other ingredients. It serves a sensory and formulation purpose rather than a therapeutic one. |
| Polyacrylate Crosspolymer-11 Film-former / texture enhancer | Polyacrylate Crosspolymer-11 is a synthetic crosslinked acrylic polymer used in skincare to provide a smooth, soft-focus texture, control viscosity, and form a thin film that improves spreadability and a velvety skin feel. It is a formulation aid rather than a biologically active treatment ingredient. |
| Citric Acid Monohydrate pH adjuster / mild exfoliant | Citric acid monohydrate is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formula pH and as a chelating agent, with mild exfoliating properties at higher concentrations and lower pH. It can promote skin cell turnover and is also found in many products as a stabilizer. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Disodium EDTA Chelating agent | Disodium EDTA is a chelating agent used in cosmetics to bind metal ions, improving product stability, preventing rancidity, and enhancing the efficacy of preservatives. It is a formulation/base ingredient rather than a treatment active. |
| Glycine Soja Seed Extract Key active Antioxidant/conditioning | Glycine Soja (soybean) Seed Extract is a soy-derived ingredient rich in isoflavones, proteins, and fatty acids used in skincare for antioxidant, moisturizing, and skin-conditioning effects. It is also studied for brightening and anti-aging benefits attributed to its phytoestrogen and antioxidant content. |
| Houttuynia Cordata Extract Key active Soothing antioxidant | Houttuynia Cordata Extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and antimicrobial properties. It is often included to calm sensitive or acne-prone skin and reduce redness. |
| Scutellaria Baicalensis Root Extract Key active Antioxidant / soothing botanical | Scutellaria Baicalensis Root Extract is a plant-derived ingredient rich in flavonoids such as baicalin, baicalein, and wogonin, valued in skincare for its antioxidant, anti-inflammatory, and skin-soothing properties. It is commonly used to help calm irritation and protect skin against environmental oxidative stress. |
| Melia Azadirachta Leaf Extract Key active Soothing/antimicrobial botanical extract | Melia Azadirachta (neem) Leaf Extract is a plant-derived ingredient valued for its antioxidant, anti-inflammatory, and antimicrobial properties, often used in skincare for soothing and conditioning effects. It contains bioactive compounds such as nimbidin and flavonoids. |
| Rehmannia Chinensis Root Extract Key active Soothing/antioxidant botanical extract | Rehmannia Chinensis Root Extract is derived from the root of the Rehmannia glutinosa plant and is used in skincare for its purported antioxidant, anti-inflammatory, and soothing properties. It contains compounds such as catalpol and iridoid glycosides that may help calm irritated skin. |
| Salix Alba Bark Extract Key active Natural exfoliant / anti-inflammatory | Salix Alba (White Willow) Bark Extract is a botanical source of salicin, which can be converted to salicylic acid, offering mild exfoliating, anti-inflammatory, and astringent properties. It is commonly used in formulations targeting acne-prone, oily, or congested skin as a gentler alternative to synthetic salicylic acid. |
| Phellodendron Amurense Bark Extract Key active Soothing / anti-inflammatory botanical | Phellodendron Amurense Bark Extract is a plant-derived extract rich in berberine and other alkaloids, used in skincare for its anti-inflammatory, antioxidant, and antimicrobial properties. It is commonly included to calm irritation, balance sebum, and support acne-prone or sensitive skin. |
| Lactobacillus Pear Juice Ferment Filtrate Skin conditioning / fermented humectant | Lactobacillus/Pear Juice Ferment Filtrate is the filtrate produced by fermenting pear juice with Lactobacillus, yielding a mix of organic acids, peptides, and metabolites used as a skin-conditioning and hydrating agent. It is valued for mild humectant, antioxidant, and skin-barrier-supporting properties in cosmetic formulations. |
| Polysorbate-20 Emulsifier / solubilizer | Polysorbate 20 is a nonionic surfactant derived from sorbitol and lauric acid, used in skincare to solubilize fragrances and essential oils and to stabilize oil-in-water emulsions. It functions primarily as a formulation aid rather than a treatment active. |
| PEG-40 Hydrogenated Castor Oil Solubilizer/emulsifier | PEG-40 Hydrogenated Castor Oil is a nonionic surfactant derived from hydrogenated castor oil reacted with ethylene oxide, widely used to dissolve fragrances and oils into water-based formulations and to stabilize emulsions. It functions as a base/formulation ingredient rather than a treatment active. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.