Below is every ingredient in Hyphen 0 1Percent Retinal Reset Serum Pro explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Chamomilla Recutita (German chamomile) flower extract is a plant-derived ingredient used in skincare for its soothing, anti-inflammatory, and antioxidant properties, attributed to compounds such as bisabolol, chamazulene, and flavonoids. It is commonly added to formulations intended to calm sensitive, irritated, or reddened skin.
Retinal (retinaldehyde) is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover, collagen synthesis, and improvement of fine lines, uneven tone, and acne. It is generally considered more potent than retinol but better tolerated than prescription retinoic acid.
Malus Domestica Fruit Cell Culture Extract is a plant stem cell extract derived from a Swiss apple variety, marketed for antioxidant protection and to support the longevity and vitality of skin cells. It is commonly included in anti-aging formulations to help reduce signs of oxidative stress and photoaging.
Tocotrienols are a subgroup of vitamin E compounds used in skincare for their antioxidant activity, helping protect skin lipids from oxidative damage caused by UV exposure and environmental stressors. They are often combined with tocopherols and other antioxidants to enhance stability and skin protection.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Irritation or sensitivity | Very rare | Purified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water. |
| Transepidermal water loss aggravation in compromised skin | Rare | Evaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent. |
| Mild irritation or stinging | Uncommon | Transient sensation typically on sensitive or compromised skin. |
| Allergic contact dermatitis | Rare | Sensitization has been documented in patch-test and case reports. |
| Redness or itching | Uncommon | Localized and usually resolves with discontinuation. |
| Photosensitivity-related reaction | Very rare | Limited anecdotal reports; not well established in research. |
| Mild transient flushing or redness | Uncommon | More likely at higher concentrations or in sensitive skin; usually subsides quickly. |
| Tingling, stinging, or burning sensation | Uncommon | Often associated with higher percentages or compromised barrier. |
| Contact irritation or itching | Rare | Generally dose-dependent and resolves with discontinuation. |
| Mild stinging or burning on application | Uncommon | Usually transient, more likely on broken or irritated skin. |
| Contact urticaria (hives) | Rare | Immediate localized wheal-and-flare reaction in allergic individuals. |
| Delayed wound healing with topical use on surgical wounds | Rare | Reported in isolated cases; clinical relevance limited. |
| Mild skin irritation | Rare | Occasional transient redness or stinging, typically in sensitive or compromised skin. |
| Contact allergic dermatitis | Very rare | Isolated sensitization reactions reported; uncommon for olive-derived esters. |
| Comedogenicity/pore congestion | Rare | Potential for clogged pores in acne-prone individuals depending on formulation. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Aqua Solvent / vehicle | Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery. |
| Centella Asiatica Extract Key active Soothing/antioxidant active | Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Aloe Barbadensis Leaf Extract Soothing/moisturizing agent | Aloe Barbadensis Leaf Extract is derived from the aloe vera plant and is used in skincare for its hydrating, soothing, and mild anti-inflammatory properties. It is commonly included as a supportive base ingredient rather than a primary treatment active. |
| Ester of Ethyl Olivate Emollient/skin-conditioning agent | Ester of Ethyl Olivate is an olive oil-derived ester used in cosmetic formulations as an emollient and skin-conditioning agent that softens skin and improves the spreadability and texture of products. It primarily functions as a base/formulation ingredient rather than a treatment active. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Olive Oil Methyl Ester Emollient / skin-conditioning agent | Olive Oil Methyl Ester is a fatty acid methyl ester derived from olive oil, used in cosmetic formulations as an emollient and skin-conditioning agent that softens skin and improves spreadability. It functions as a base/carrier ingredient rather than a therapeutic active. |
| Chamomilla Recutita Flower Extract Key active Soothing/anti-inflammatory botanical extract | Chamomilla Recutita (German chamomile) flower extract is a plant-derived ingredient used in skincare for its soothing, anti-inflammatory, and antioxidant properties, attributed to compounds such as bisabolol, chamazulene, and flavonoids. It is commonly added to formulations intended to calm sensitive, irritated, or reddened skin. |
| Propanediol Humectant/solvent | Propanediol is a plant-derived glycol used in skincare as a humectant, solvent, and penetration enhancer that improves moisturization and the spreadability of formulations. It also helps solubilize other ingredients and can boost the efficacy of certain actives. |
| Squalane Emollient / occlusive moisturizer | Squalane is a saturated, stable hydrocarbon derived from squalene (sourced from plants like olives or sugarcane, or shark liver) used as a lightweight emollient that softens skin and reinforces the skin barrier by reducing transepidermal water loss. It is well tolerated, non-comedogenic for most users, and serves as a base or carrier ingredient rather than a therapeutic active. |
| Prunus Amygdalus Dulcis Oil Emollient / skin-conditioning oil | Prunus Amygdalus Dulcis Oil (sweet almond oil) is a non-volatile plant oil rich in oleic and linoleic acids used to soften, soothe, and reduce transepidermal water loss in skincare formulations. It functions primarily as an emollient and occlusive base ingredient rather than a treatment active. |
| PEG-100 Stearate Emulsifier/surfactant | PEG-100 Stearate is a polyethylene glycol ester of stearic acid used as a nonionic surfactant and emulsifier to stabilize oil-in-water formulations and improve skin feel. It functions as a formulation base ingredient rather than a therapeutic active. |
| Glyceryl Stearate Emulsifier/emollient | Glyceryl Stearate is a glycerol ester of stearic acid widely used as a non-ionic emulsifier and emollient to stabilize oil-in-water formulations and improve skin feel. It functions as a base/formulation ingredient rather than a therapeutic active. |
| Retinal Key active Retinoid (vitamin A derivative) | Retinal (retinaldehyde) is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover, collagen synthesis, and improvement of fine lines, uneven tone, and acne. It is generally considered more potent than retinol but better tolerated than prescription retinoic acid. |
| Malus Domestica Fruit Cell Culture Extract Key active Antioxidant / skin-conditioning | Malus Domestica Fruit Cell Culture Extract is a plant stem cell extract derived from a Swiss apple variety, marketed for antioxidant protection and to support the longevity and vitality of skin cells. It is commonly included in anti-aging formulations to help reduce signs of oxidative stress and photoaging. |
| Tocotrienols Key active Antioxidant | Tocotrienols are a subgroup of vitamin E compounds used in skincare for their antioxidant activity, helping protect skin lipids from oxidative damage caused by UV exposure and environmental stressors. They are often combined with tocopherols and other antioxidants to enhance stability and skin protection. |
| Tocopherol Key active Antioxidant | Tocopherol (vitamin E) is a lipid-soluble antioxidant used in skincare to protect skin and formulations from oxidative damage caused by free radicals and UV exposure. It also functions as a skin-conditioning and emollient agent and can stabilize oils against rancidity. |
| Ascorbyl Palmitate Key active Antioxidant / Vitamin C derivative | Ascorbyl palmitate is a lipid-soluble, more stable ester of vitamin C (ascorbic acid) used as an antioxidant in skincare formulations. It can help protect formulas from oxidation and may offer some skin antioxidant benefits, though its conversion to active ascorbic acid in skin is limited. |
| Panthenol Humectant / skin-conditioning agent | Panthenol (provitamin B5) is converted to pantothenic acid in the skin, where it acts as a humectant and helps support skin barrier function and hydration. It is also used for its soothing and mild anti-inflammatory properties in topical formulations. |
| Arginine Amino acid / pH adjuster & conditioning agent | Arginine is a basic amino acid used in skincare primarily as a pH buffer/neutralizer and humectant-like conditioning agent that supports skin hydration and barrier function. It is generally well tolerated and often paired with acidic ingredients to balance formulation pH. |
| Avena Sativa Kernel Extract Key active Soothing / anti-irritant | Avena Sativa (oat) Kernel Extract is derived from oat seeds and is used in skincare for its soothing, anti-inflammatory, and skin-barrier-supporting properties, largely attributed to avenanthramides, beta-glucans, and saponins. It is commonly incorporated to calm irritation, reduce itching, and improve hydration in sensitive or compromised skin. |
| Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Thickener / stabilizer | Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic acrylic-based polymer used as a rheology modifier, thickening agent, and emulsion stabilizer in skincare and cosmetic formulations. It helps create smooth, stable gels and creams without contributing active treatment benefits to the skin. |
| Saccharide Isomerate Humectant / moisturizer | Saccharide Isomerate is a plant-derived carbohydrate complex that binds to the skin's keratin to provide long-lasting hydration and improve moisture retention. It is structurally similar to carbohydrates naturally found in the skin's upper layers. |
| Allantoin Key active Soothing/skin-conditioning agent | Allantoin is a naturally derived or synthetically produced compound used in skincare for its soothing, moisturizing, and keratolytic (skin-softening) properties. It promotes cell proliferation and helps calm irritation, commonly appearing in creams, lotions, and after-sun products. |
| Hydrogenated Polydecene Emollient / skin-conditioning agent | Hydrogenated Polydecene is a synthetic hydrocarbon emollient derived from hydrogenated polydecene oligomers, used to provide a lightweight, non-greasy occlusive film that softens skin and improves spreadability in cosmetic formulations. It serves as a base or texture-enhancing ingredient rather than a biologically active treatment. |
| Trideceth-6 Surfactant/emulsifier | Trideceth-6 is a polyethylene glycol ether of tridecyl alcohol used as a nonionic surfactant, emulsifier, and solubilizer in cosmetic formulations. It helps blend oil and water phases and disperse fragrances or other oily components in water-based products. |
| Sorbitan Laurate Emulsifier / surfactant | Sorbitan Laurate is a non-ionic emulsifier and surfactant derived from sorbitol and lauric acid, used to stabilize oil-in-water emulsions and improve texture in skincare formulations. It functions primarily as a base/formulation ingredient rather than a treatment active. |
| Polysorbate 80 Emulsifier / surfactant / solubilizer | Polysorbate 80 is a nonionic surfactant derived from sorbitol and oleic acid, used to emulsify oil and water phases and solubilize fragrances and oils in cosmetic and pharmaceutical formulations. It functions as a formulation aid rather than a therapeutic active. |
| Hyaluronic Acid Key active Humectant / hydrating agent | Hyaluronic acid is a glycosaminoglycan that attracts and binds water to the skin, helping to maintain hydration and improve the appearance of plumpness and smoothness. It is widely used in moisturizers and serums and is generally well tolerated across skin types. |
| Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Antioxidant/stabilizer | Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate is a hindered-phenol antioxidant (also known as the industrial stabilizer Irganox 1010) used in cosmetic formulations to prevent oxidation and rancidity of oils, fats, and other ingredients. It functions primarily as a formulation stabilizer rather than a skin-active treatment. |
| Sodium Citrate pH adjuster / chelating agent | Sodium citrate is the sodium salt of citric acid used in skincare primarily as a buffering agent to stabilize formulation pH and as a chelator that binds metal ions to improve product stability. It is a base/formulation ingredient rather than a therapeutic active. |
| Sodium Gluconate Chelating agent / skin-conditioning | Sodium gluconate is the sodium salt of gluconic acid used in skincare primarily as a chelating agent to bind metal ions and stabilize formulations, with secondary humectant and skin-conditioning properties. It is generally considered a base/formulation ingredient rather than an active treatment. |
| Inulin Lauryl Carbamate Emulsifier / surfactant | Inulin Lauryl Carbamate is a plant-derived, sugar-based emulsifier produced by reacting inulin with lauryl groups. It is used to stabilize oil-in-water emulsions and improve texture in creams and lotions. |
| Sucrose Laurate Emulsifier/surfactant | Sucrose Laurate is a sugar-based ester (sucrose combined with lauric acid) used in skincare as a mild, biodegradable emulsifier, surfactant, and skin-conditioning agent. It helps stabilize oil-in-water formulations and improves texture while being generally well tolerated. |
| 1,2-Hexanediol Humectant / preservative booster | 1,2-Hexanediol is a synthetic diol used in skincare as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, often allowing reduced or preservative-free systems. It helps maintain product stability while contributing mild moisturizing properties. |
| Hydroxyacetophenone Antioxidant / soothing agent | Hydroxyacetophenone (acetophenone-based compound, often 4'-hydroxyacetophenone) is used in skincare primarily as an antioxidant and skin-conditioning agent that can also enhance the stability and efficacy of preservative systems. It is valued for its soothing properties and helps neutralize free radicals while reducing potential irritation from other formulation components. |
| Lecithin Emollient / Emulsifier | Lecithin is a naturally occurring phospholipid (commonly derived from soybean or egg) used in skincare as an emulsifier, emollient, and penetration enhancer. It helps stabilize oil-and-water formulations and supports the skin barrier by mimicking natural lipids. |
| Xanthan Gum Thickener/stabilizer | Xanthan gum is a polysaccharide produced by bacterial fermentation, used in skincare as a thickening, gelling, and emulsion-stabilizing agent. It improves product texture and suspension of ingredients without contributing active treatment effects. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.