Below is every ingredient in Skininspired Retinol Face Night Serum explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Retinol is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover and stimulating collagen synthesis. It is widely used to address fine lines, photoaging, and acne.
Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier.
Ubiquinone (Coenzyme Q10) is a fat-soluble, naturally occurring antioxidant used in skincare to neutralize free radicals and support cellular energy production. It is commonly included in anti-aging formulations to help reduce the appearance of fine lines and oxidative skin damage.
Allantoin is a naturally derived or synthetically produced compound used in skincare for its soothing, moisturizing, and keratolytic (skin-softening) properties. It promotes cell proliferation and helps calm irritation, commonly appearing in creams, lotions, and after-sun products.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Skin irritation or sensitivity | Very rare | Purified water is essentially inert; reactions are attributable to other formula components, not the water itself. |
| Transient skin barrier disruption from excessive exposure | Rare | Prolonged or repeated wetting can contribute to mild barrier compromise, but this relates to usage patterns rather than the ingredient. |
| Mild skin irritation | Rare | Occasional transient irritation reported in sensitive individuals. |
| Allergic contact dermatitis | Very rare | Isolated sensitization reports; generally well tolerated. |
| Comedogenicity (pore clogging) | Rare | Low comedogenic potential but possible in acne-prone skin. |
| Skin irritation or redness | Rare | Generally well tolerated; mild irritation reported infrequently. |
| Comedogenic reactions | Rare | Possible pore-clogging in acne-prone individuals, though it is widely regarded as low risk. |
| Contact allergy/sensitization | Very rare | Silicones are low-allergenicity; documented allergic reactions are exceptional. |
| Eye irritation | Rare | Possible transient stinging if product enters the eyes. |
| Enhanced penetration of co-formulated irritants | Uncommon | As a penetration enhancer it may increase absorption and irritation potential of other actives. |
| Comedogenicity (clogged pores/acne) | Common | Considered comedogenic on acne-prone or oily skin; may worsen breakouts. |
| Irritant contact reaction | Rare | Mild stinging or irritation, more likely with damaged skin. |
| Folliculitis | Very rare | Follicular inflammation associated with heavy occlusive application. |
| Mild transient flushing or redness | Uncommon | More likely at higher concentrations or in sensitive skin; usually subsides quickly. |
| Tingling, stinging, or burning sensation | Uncommon | Often associated with higher percentages or compromised barrier. |
| Contact irritation or itching | Rare | Generally dose-dependent and resolves with discontinuation. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Purified Water Solvent/vehicle | Purified water is a highly filtered, deionized water used as the primary solvent and base in most skincare formulations. It dissolves water-soluble ingredients and provides the medium in which other components are dispersed. |
| Isoamyl Laurate Emollient | Isoamyl Laurate is a plant-derived ester (from isoamyl alcohol and lauric acid) used as a lightweight, fast-spreading emollient that improves skin feel and product texture. It functions to soften and condition the skin and acts as a natural alternative to silicones. |
| Ceto Cetyl Alcohol Emollient / emulsifier | Cetostearyl alcohol (a blend of cetyl and stearyl fatty alcohols) is a fatty alcohol used as an emollient, thickener, and emulsion stabilizer in creams and lotions. It softens skin and helps keep oil and water phases blended rather than acting as a treatment active. |
| Cyclopentasiloxane Emollient/silicone | Cyclopentasiloxane is a volatile cyclic silicone widely used in skincare and cosmetics to impart a smooth, silky feel and spreadability before evaporating, leaving no greasy residue. It also serves as a carrier and helps reduce tackiness in formulations. |
| Propanediol Humectant/solvent | Propanediol is a plant-derived glycol used in skincare as a humectant, solvent, and penetration enhancer that improves moisturization and the spreadability of formulations. It also helps solubilize other ingredients and can boost the efficacy of certain actives. |
| Cocoa Butter Emollient/occlusive moisturizer | Cocoa butter is a fat extracted from cocoa beans used in skincare to soften skin and form an occlusive barrier that reduces transepidermal water loss. It is commonly used in lotions, balms, and lip products as a base/emollient ingredient. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Tapioca Starch Absorbent / texture enhancer | Tapioca starch is a plant-derived polysaccharide powder used in cosmetics to absorb excess oil and moisture, impart a soft matte finish, and improve the sensory texture of formulations. It functions as a base/formulation ingredient rather than a therapeutic active. |
| Polymethylsilsesquioxane Texture enhancer / mattifying agent | Polymethylsilsesquioxane is a silicone-based spherical powder used in skincare and cosmetics to impart a smooth, soft-focus, mattifying feel and improve spreadability. It is a formulation/texture ingredient rather than a treatment active. |
| Sodium Polyacrylate Thickener / absorbent | Sodium polyacrylate is a superabsorbent acrylic-acid polymer used in skincare as a thickening, stabilizing, and water-binding agent that can hold large amounts of liquid to create gel-like textures. It functions as a formulation and texture-enhancing ingredient rather than a biologically active treatment. |
| Dimethicone Emollient/occlusive (silicone) | Dimethicone is a silicone-based polymer used in skincare to soften skin, smooth texture, and form a breathable protective barrier that reduces transepidermal water loss. It is widely used as a base/formulation ingredient rather than a therapeutic active. |
| Cyclopentasiloxane Emollient/silicone | Cyclopentasiloxane is a volatile cyclic silicone widely used in skincare and cosmetics to impart a smooth, silky feel and spreadability before evaporating, leaving no greasy residue. It also serves as a carrier and helps reduce tackiness in formulations. |
| Trideceth-6 Surfactant/emulsifier | Trideceth-6 is a polyethylene glycol ether of tridecyl alcohol used as a nonionic surfactant, emulsifier, and solubilizer in cosmetic formulations. It helps blend oil and water phases and disperse fragrances or other oily components in water-based products. |
| PEG/PPG-18/18 Dimethicone Silicone-based emulsifier/conditioning agent | PEG/PPG-18/18 Dimethicone is a water-dispersible silicone surfactant used to emulsify, stabilize, and impart a smooth, silky feel to skincare and cosmetic formulations. It functions primarily as an emulsifier and skin-conditioning agent rather than a therapeutic active. |
| Butyrospermum Parkii Butter Emollient/occlusive | Butyrospermum Parkii Butter (shea butter) is a plant-derived fat used in skincare as an emollient and occlusive agent to soften skin and reduce transepidermal water loss. It is rich in fatty acids and unsaponifiables that condition and help maintain the skin barrier. |
| Emulsifying Wax Emulsifier / texture enhancer | Emulsifying wax is a blend of fatty alcohols and surfactants used to bind oil and water phases into stable creams and lotions. It functions as a formulation base ingredient, improving texture and consistency rather than treating skin conditions. |
| Squalane Emollient / occlusive moisturizer | Squalane is a saturated, stable hydrocarbon derived from squalene (sourced from plants like olives or sugarcane, or shark liver) used as a lightweight emollient that softens skin and reinforces the skin barrier by reducing transepidermal water loss. It is well tolerated, non-comedogenic for most users, and serves as a base or carrier ingredient rather than a therapeutic active. |
| Olive Oil PEG-7 Esters Emollient/emulsifier | Olive Oil PEG-7 Esters is a water-dispersible derivative of olive oil produced by reaction with polyethylene glycol, used in skincare as an emollient, emulsifier, and mild solubilizer. It conditions skin and helps blend oil and water phases in formulations. |
| Behenyl Alcohol Emollient / Thickener | Behenyl alcohol is a fatty alcohol derived from behenic acid that functions as an emollient, thickening agent, and emulsion stabilizer in cosmetic and skincare formulations. It helps soften the skin and improve product texture and stability. |
| Water Solvent/vehicle | Water is the most common base ingredient in cosmetic formulations, serving as a solvent that dissolves other ingredients and forms the bulk of emulsions and aqueous solutions. It is generally considered safe and non-irritating. |
| Copernicia Cerifera Cera Emollient/Thickener (wax) | Copernicia Cerifera Cera, commonly known as carnauba wax, is a plant-derived wax obtained from the leaves of the Brazilian palm. It is used in cosmetics as a thickening, structuring, and film-forming agent, particularly in lipsticks, balms, and solid formulations. |
| Retinol Key active Vitamin A derivative / anti-aging active | Retinol is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover and stimulating collagen synthesis. It is widely used to address fine lines, photoaging, and acne. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Propanediol Humectant/solvent | Propanediol is a plant-derived glycol used in skincare as a humectant, solvent, and penetration enhancer that improves moisturization and the spreadability of formulations. It also helps solubilize other ingredients and can boost the efficacy of certain actives. |
| BHT Antioxidant/preservative | BHT (butylated hydroxytoluene) is a synthetic phenolic antioxidant used in small amounts to prevent oxidation and rancidity of oils, fragrances, and other unstable components, helping maintain product stability and shelf life. |
| Xanthan Gum Thickener/stabilizer | Xanthan gum is a polysaccharide produced by bacterial fermentation, used in skincare as a thickening, gelling, and emulsion-stabilizing agent. It improves product texture and suspension of ingredients without contributing active treatment effects. |
| Sodium Cocoamphoacetate Mild amphoteric surfactant/cleansing agent | Sodium cocoamphoacetate is a coconut-derived amphoteric surfactant used in cleansers, shampoos, and body washes to provide gentle cleansing, foaming, and to reduce the irritation potential of harsher anionic surfactants. It is valued for its mildness and is commonly found in baby and sensitive-skin formulations. |
| Tocopheryl Acetate Key active Antioxidant | Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier. |
| Ubiquinone Key active Antioxidant | Ubiquinone (Coenzyme Q10) is a fat-soluble, naturally occurring antioxidant used in skincare to neutralize free radicals and support cellular energy production. It is commonly included in anti-aging formulations to help reduce the appearance of fine lines and oxidative skin damage. |
| C12-15 Alkyl Benzoate Emollient / texture enhancer | C12-15 Alkyl Benzoate is a lightweight ester emollient widely used in skincare and cosmetics to improve spreadability, provide a smooth non-greasy skin feel, and act as a solvent and mild antimicrobial booster. It is considered a base/formulation ingredient rather than a treatment active. |
| Allantoin Key active Soothing/skin-conditioning agent | Allantoin is a naturally derived or synthetically produced compound used in skincare for its soothing, moisturizing, and keratolytic (skin-softening) properties. It promotes cell proliferation and helps calm irritation, commonly appearing in creams, lotions, and after-sun products. |
| DMDM Hydantoin Preservative (antimicrobial, formaldehyde-releaser) | DMDM Hydantoin is a formaldehyde-releasing preservative used in cosmetics and personal care products to prevent microbial growth and extend shelf life. It works by slowly releasing small amounts of formaldehyde into the formulation. |
| Methylchloroisothiazolinone Preservative | Methylchloroisothiazolinone (MCI) is a synthetic isothiazolinone preservative used at very low concentrations to prevent microbial growth in cosmetics and personal care products, often combined with methylisothiazolinone. It is typically restricted to rinse-off products due to its sensitizing potential. |
| Methylisothiazolinone Preservative | Methylisothiazolinone (MI) is a synthetic isothiazolinone preservative used in cosmetics and personal care products to prevent microbial growth. It is effective at low concentrations but is recognized as a significant contact allergen. |
| Parfum Fragrance | Parfum (fragrance) is a blend of aromatic compounds added to cosmetic products to impart a pleasant scent or mask the base odor of other ingredients. It serves a sensory/formulation purpose rather than providing any skin benefit. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.