Below is every ingredient in PeptiCharge Rejuvenating Night Crème with Multi-Peptides, Exosomes & Bifida Ferment explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
"Supporting firmness" refers to ingredients (such as peptides, retinoids, vitamin C, and niacinamide) that aim to enhance skin's structural proteins and elasticity, helping to improve apparent firmness and reduce sagging. Effects are typically gradual and depend on the specific active and concentration used.
Bifida Ferment Lysate is a lysate of fermented Bifidobacterium cultures used in skincare for its skin-conditioning, soothing, and barrier-supporting properties. It is studied for improving skin hydration, resilience, and protection against environmental stressors such as UV-induced damage.
Myristoyl Tetrapeptide-34 is a lipidated synthetic peptide used in cosmetic formulations, marketed for skin-conditioning and to support a smoother, more even-looking skin surface. As a relatively new and proprietary ingredient, it lacks extensive independent peer-reviewed safety and efficacy data.
Myristoyl Tetrapeptide-6 is a synthetic lipidated signal peptide used in cosmetic formulations to support extracellular matrix proteins and reduce the appearance of fine lines and wrinkles. The myristoyl group enhances lipid solubility and skin penetration.
Myristoyl Tripeptide-31 is a lipidated signal peptide used in cosmetic formulations to support skin firmness and reduce the appearance of fine lines, theorized to modulate cellular signaling and extracellular matrix proteins. Clinical data are limited and largely manufacturer-derived.
Palmitoyl Pentapeptide-4 (Matrixyl, pal-KTTKS) is a lipidated peptide that signals fibroblasts to increase production of collagen, elastin, and other extracellular matrix components. It is used in topical formulations to help reduce the appearance of fine lines and improve skin firmness.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient irritation or stinging | Common | Often seen with retinoids or vitamin C, especially early in use |
| Erythema (redness) | Common | Usually mild and resolves with continued use or reduced frequency |
| Dryness or flaking | Uncommon | More likely with retinoid-based firming actives |
| Contact dermatitis | Rare | Allergic or irritant reaction to specific peptides or excipients |
| Photosensitivity | Rare | Associated mainly with retinoids; daytime sun protection advised |
| Severe allergic reaction | Very rare | Hypersensitivity requiring discontinuation |
| No direct adverse effects (not an ingredient) | Very rare | As a property rather than a substance, elasticity itself causes no reactions; any effects stem from the actual formulation ingredients used to support it. |
| Mild skin irritation | Rare | Occasional transient redness or stinging, generally in sensitive skin. |
| Contact dermatitis/allergic reaction | Very rare | Hydrocarbon emollients are considered low-sensitizing; reports are minimal. |
| Pore congestion/comedogenicity | Very rare | Generally regarded as low comedogenic risk, but heavy occlusive layering may contribute in acne-prone individuals. |
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| supporting firmness Key active firming/skin-supporting | "Supporting firmness" refers to ingredients (such as peptides, retinoids, vitamin C, and niacinamide) that aim to enhance skin's structural proteins and elasticity, helping to improve apparent firmness and reduce sagging. Effects are typically gradual and depend on the specific active and concentration used. |
| elasticity Skin firmness/elasticity descriptor (not a discrete ingredient) | "Elasticity" is not a specific skincare ingredient but a property of skin describing its ability to stretch and return to shape, largely governed by dermal elastin and collagen. In cosmetic labeling it usually refers to a claimed benefit rather than a single compound, so it has no inherent chemical profile or side effects of its own. |
| C12-17 Alkane Emollient/solvent | C12-17 Alkane is a blend of branched-chain saturated hydrocarbons derived as a silicone alternative, used as a lightweight emollient and spreading agent. It imparts a smooth, non-greasy skin feel and aids the dispersion of other ingredients in cosmetic formulations. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Xylitol Humectant / moisturizer | Xylitol is a sugar alcohol used in topical formulations as a humectant that helps attract and retain moisture in the skin, and it may support the skin's microbiome and barrier function. It is generally well tolerated and considered safe for topical use. |
| Glyceryl Stearate Emulsifier/emollient | Glyceryl Stearate is a glycerol ester of stearic acid widely used as a non-ionic emulsifier and emollient to stabilize oil-in-water formulations and improve skin feel. It functions as a base/formulation ingredient rather than a therapeutic active. |
| PEG-100 Stearate Emulsifier/surfactant | PEG-100 Stearate is a polyethylene glycol ester of stearic acid used as a nonionic surfactant and emulsifier to stabilize oil-in-water formulations and improve skin feel. It functions as a formulation base ingredient rather than a therapeutic active. |
| Betaine Humectant / osmolyte | Betaine is a naturally derived amino acid derivative (trimethylglycine) used in skincare as a humectant and osmoprotectant that attracts and retains moisture while helping stabilize skin barrier function. It also improves the texture and mildness of formulations. |
| Cetyl Palmitate Emollient / Thickener | Cetyl palmitate is a waxy ester of cetyl alcohol and palmitic acid used as an emollient, thickening agent, and emulsion stabilizer in creams, lotions, and cosmetics. It softens skin and helps provide a smooth texture and consistent product structure. |
| Isononyl Isononanoate Emollient/skin-conditioning agent | Isononyl Isononanoate is a synthetic ester emollient used in cosmetics to impart a light, silky, non-greasy skin feel and to aid the spreadability of formulations. It functions as a base/texture ingredient rather than a treatment active. |
| Cetearyl Alcohol Emollient/emulsifier | Cetearyl alcohol is a fatty alcohol blend (cetyl and stearyl alcohol) used in skincare as an emollient, emulsion stabilizer, and thickening agent. It helps soften skin and keep oil and water phases blended in creams and lotions. |
| Inositol Humectant / conditioning agent | Inositol is a sugar alcohol (carbocyclic polyol) used in skincare as a moisturizing and conditioning ingredient that supports skin hydration and barrier function. It is generally considered mild and well tolerated in topical formulations. |
| Bifida Ferment Lysate Key active Probiotic-derived skin conditioning agent | Bifida Ferment Lysate is a lysate of fermented Bifidobacterium cultures used in skincare for its skin-conditioning, soothing, and barrier-supporting properties. It is studied for improving skin hydration, resilience, and protection against environmental stressors such as UV-induced damage. |
| Myristoyl Tetrapeptide-34 Key active Signal peptide / conditioning agent | Myristoyl Tetrapeptide-34 is a lipidated synthetic peptide used in cosmetic formulations, marketed for skin-conditioning and to support a smoother, more even-looking skin surface. As a relatively new and proprietary ingredient, it lacks extensive independent peer-reviewed safety and efficacy data. |
| Myristoyl Tetrapeptide-6 Key active Signal peptide / anti-aging active | Myristoyl Tetrapeptide-6 is a synthetic lipidated signal peptide used in cosmetic formulations to support extracellular matrix proteins and reduce the appearance of fine lines and wrinkles. The myristoyl group enhances lipid solubility and skin penetration. |
| Myristoyl Tripeptide-31 Key active Signal peptide / anti-aging active | Myristoyl Tripeptide-31 is a lipidated signal peptide used in cosmetic formulations to support skin firmness and reduce the appearance of fine lines, theorized to modulate cellular signaling and extracellular matrix proteins. Clinical data are limited and largely manufacturer-derived. |
| Palmitoyl Pentapeptide-4 Key active Anti-aging signal peptide | Palmitoyl Pentapeptide-4 (Matrixyl, pal-KTTKS) is a lipidated peptide that signals fibroblasts to increase production of collagen, elastin, and other extracellular matrix components. It is used in topical formulations to help reduce the appearance of fine lines and improve skin firmness. |
| Methyl Undecenoyl Leucinate Key active Sebum-regulating / anti-acne active | Methyl Undecenoyl Leucinate is a lipoamino acid derivative combining undecylenic acid and the amino acid leucine, used in skincare to help regulate sebum production and reduce oily-skin and blemish-related concerns. It is typically incorporated into treatments targeting acne-prone, oily, or combination skin. |
| Copper Tripeptide-1 Key active Signal peptide / skin-conditioning agent | Copper Tripeptide-1 (GHK-Cu) is a copper-bound peptide used in skincare for its reported ability to support collagen and elastin synthesis, wound healing, and antioxidant activity. It is considered a bioactive cosmetic ingredient targeting signs of skin aging. |
| Laminaria Digitata (Oarweed) Extract Key active Conditioning/antioxidant marine extract | Laminaria Digitata (Oarweed) Extract is a brown seaweed-derived ingredient rich in polysaccharides, minerals, and antioxidants, used in skincare for its hydrating, soothing, and conditioning properties. It is valued for film-forming and humectant effects that improve skin moisture and texture. |
| Hydrogenated Lecithin Emollient / Emulsifier | Hydrogenated lecithin is a phospholipid derived from lecithin through hydrogenation, used in skincare as an emulsifier, emollient, and skin-conditioning agent. It also helps stabilize formulations and form liposomes that can aid delivery of other ingredients. |
| Cetyl-PG Hydroxyethyl Palmitamide Skin-conditioning emollient / pseudo-ceramide | Cetyl-PG Hydroxyethyl Palmitamide is a synthetic pseudo-ceramide used to mimic natural skin ceramides, helping to support the skin barrier and reduce transepidermal water loss. It functions as an emollient and moisturizing agent commonly found in barrier-repair and dry-skin formulations. |
| Ceramide EOP Skin barrier lipid | Ceramide EOP is a long-chain omega-hydroxy ceramide that helps form and maintain the skin's lipid barrier, supporting moisture retention and reducing transepidermal water loss. It is commonly used in moisturizers and barrier-repair formulations. |
| Ceramide NS/Ceramide NG Skin-barrier lipid / moisturizer | Ceramide NS (Ceramide 2/NG) is a naturally occurring sphingolipid that helps form and maintain the skin's lipid barrier, reducing transepidermal water loss and improving hydration. It is widely used in moisturizers and barrier-repair formulations. |
| Ceramide NP Skin-barrier replenishing lipid / emollient | Ceramide NP (formerly ceramide 3) is a naturally occurring sphingolipid that helps restore and maintain the skin's lipid barrier, reducing transepidermal water loss and improving hydration. It is widely used in moisturizers and barrier-repair formulations. |
| Ceramide AS Skin-barrier lipid / emollient | Ceramide AS is a synthetic sphingolipid that mimics naturally occurring skin ceramides, helping restore and reinforce the stratum corneum barrier and reduce transepidermal water loss. It is commonly used in moisturizers and barrier-repair formulations. |
| Ceramide AP Skin barrier lipid / moisturizer | Ceramide AP (ceramide 6-II) is a naturally occurring sphingolipid that helps restore and maintain the skin's barrier function and reduce transepidermal water loss. It is commonly used in moisturizers and barrier-repair formulations, often combined with other ceramides, cholesterol, and fatty acids. |
| Cholesterol Skin barrier lipid / emollient | Cholesterol is a naturally occurring lipid found in the skin's stratum corneum that, alongside ceramides and fatty acids, helps maintain the skin barrier and prevent transepidermal water loss. In skincare formulations it functions as an emollient and barrier-repair agent that improves hydration and skin resilience. |
| 2-Hexanediol Humectant/preservative-booster | 1,2-Hexanediol (commonly written 2-hexanediol) is a multifunctional diol used in skincare primarily as a humectant, solvent, and preservative-enhancing agent that improves the antimicrobial efficacy of formulations. It is generally well tolerated and considered a base/formulation ingredient rather than a treatment active. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Sodium PCA Humectant | Sodium PCA (sodium pyrrolidone carboxylic acid) is the sodium salt of pyroglutamic acid and a component of the skin's natural moisturizing factor (NMF). It is widely used in cosmetics as a water-binding humectant to hydrate and soften the skin. |
| Sodium Lactate Humectant / NMF component | Sodium lactate is the sodium salt of lactic acid and a key component of skin's natural moisturizing factor (NMF), used to hydrate the skin and buffer formulation pH. It also has mild exfoliating and humectant properties that help maintain skin moisture and barrier function. |
| PCA Humectant / NMF component | PCA (pyrrolidone carboxylic acid), often as sodium PCA, is a naturally occurring component of skin's natural moisturizing factor (NMF) that attracts and binds water to the stratum corneum. It is used in skincare to improve hydration and skin softness. |
| Serine Humectant / amino acid | Serine is a naturally occurring amino acid and component of the skin's natural moisturizing factor (NMF), used in skincare to support hydration and help maintain the skin barrier. It is typically incorporated as a conditioning and water-binding agent rather than a clinical treatment active. |
| Alanine Amino acid / humectant | Alanine is a small non-essential amino acid used in skincare as a humectant and component of the skin's natural moisturizing factor (NMF), helping to maintain hydration and support the skin barrier. It is also used as a buffering agent and to improve the feel of formulations. |
| Glycine Amino acid / humectant | Glycine is a small amino acid used in skincare as a humectant and conditioning agent, supporting skin hydration and acting as a building block for collagen and natural moisturizing factor. It is generally considered well-tolerated and is often included as part of moisturizing or barrier-support formulations. |
| Glutamic Acid Humectant / amino acid | Glutamic acid is a naturally occurring amino acid used in skincare as a humectant and component of the skin's natural moisturizing factor (NMF), helping to maintain hydration and support the skin barrier. It is also used as a pH adjuster and in some formulations to enhance moisturization. |
| Lysine HCl Conditioning/amino acid | Lysine HCl is the hydrochloride salt of the essential amino acid L-lysine, used in skincare primarily as a skin-conditioning and humectant agent that supports the skin's natural moisturizing factor and protein structure. It is generally considered a supportive formulation ingredient rather than a clinically proven active. |
| Threonine Amino acid / skin conditioning agent | Threonine is an essential amino acid used in skincare primarily as a humectant and skin-conditioning agent, helping support hydration and the skin's natural moisturizing factor. It is also a building block for proteins such as collagen and elastin. |
| Arginine Amino acid / pH adjuster & conditioning agent | Arginine is a basic amino acid used in skincare primarily as a pH buffer/neutralizer and humectant-like conditioning agent that supports skin hydration and barrier function. It is generally well tolerated and often paired with acidic ingredients to balance formulation pH. |
| Proline Amino acid / skin-conditioning agent | Proline is a non-essential amino acid and a key component of collagen, used in skincare as a humectant and skin-conditioning agent to support hydration and the skin barrier. It is generally well tolerated and often included in formulations for its moisturizing and structural-protein-supporting properties. |
| Pistacia Lentiscus Gum Key active Astringent / antimicrobial | Pistacia Lentiscus Gum (mastic) is a resinous exudate from the mastic tree used in skincare for its astringent, antibacterial, and antioxidant properties. It is often incorporated for oil control, soothing, and as a film-forming agent. |
| Lecithin Emollient / Emulsifier | Lecithin is a naturally occurring phospholipid (commonly derived from soybean or egg) used in skincare as an emulsifier, emollient, and penetration enhancer. It helps stabilize oil-and-water formulations and supports the skin barrier by mimicking natural lipids. |
| Pentylene Glycol Humectant / solvent / preservative-booster | Pentylene glycol is a glycol used in cosmetics as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, helping reduce reliance on traditional preservatives. It improves skin hydration and aids the delivery and stability of other ingredients. |
| Glyceryl Caprylate/Caprate Emollient/emulsifier & co-preservative | Glyceryl Caprylate/Caprate is a mixture of glycerin esters of caprylic and capric acids used in skincare as a skin-conditioning emollient, emulsifier, and mild antimicrobial co-preservative. It improves texture and spreadability while helping stabilize formulations. |
| Hexyldecanol Emollient / fatty alcohol | Hexyldecanol is a branched-chain fatty alcohol used in skincare as an emollient and skin-conditioning agent that softens skin and helps stabilize emulsions. It contributes to texture and spreadability in cosmetic formulations. |
| Bisabolol Key active Soothing/anti-inflammatory agent | Bisabolol is a naturally derived (typically from chamomile) or synthetic terpene alcohol used in skincare for its anti-inflammatory, soothing, and skin-conditioning properties. It is also reported to enhance penetration of other ingredients and offers mild antimicrobial activity. |
| Cetyl Hydroxyproline Palmitamide Emollient / skin-conditioning agent | Cetyl Hydroxyproline Palmitamide is a lipophilic amino acid (hydroxyproline) derivative used in skincare as an emollient and skin-conditioning agent, valued for its ability to support the skin's lipid barrier and improve moisturization. It is structurally a fatty-acid amide that mimics components of the skin barrier, contributing to a smoother, softer skin feel. |
| Stearic Acid Emulsifier / thickener | Stearic acid is a saturated long-chain fatty acid widely used in cosmetics as an emulsifier, thickening agent, and emollient to stabilize creams and lotions. It is generally considered a base/formulation ingredient rather than a therapeutic active. |
| Brassica Campestris (Rapeseed) Sterols Emollient / skin-conditioning agent | Brassica Campestris (Rapeseed) Sterols are plant-derived phytosterols used in skincare to soften skin, reinforce the lipid barrier, and stabilize emulsions. They function primarily as a base/formulation conditioning agent rather than a targeted treatment active. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Bacillus/Soybean Ferment Extract Key active Skin conditioning / moisturizing humectant | Bacillus/Soybean Ferment Extract is a fermentation-derived ingredient produced by culturing soybeans with Bacillus species, yielding peptides, amino acids, and polysaccharides (including polyglutamic acid). It is used in skincare primarily for its hydrating, conditioning, and skin-soothing properties. |
| Folic Acid Key active Antioxidant / conditioning agent | Folic acid (vitamin B9) is used in topical skincare as an antioxidant and skin-conditioning ingredient, with some research suggesting it may support skin renewal and help mitigate signs of environmental stress. Evidence for topical efficacy is limited compared to its established role in dietary supplementation. |
| Dipotassium Glycyrrhizate Key active Anti-inflammatory/soothing agent | Dipotassium glycyrrhizate is a water-soluble salt derived from licorice root (glycyrrhizic acid) used in skincare for its anti-inflammatory, soothing, and antioxidant properties. It is commonly added to formulations to calm irritation, redness, and sensitivity. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.