Below is every ingredient in Klairs Supple Preparation Facial Toner/Reviews explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Dimethyl sulfone (MSM, methylsulfonylmethane) is an organic sulfur compound used in topical formulations for its purported skin-conditioning, anti-inflammatory, and barrier-supporting properties. It is sometimes included to help improve skin tone, hydration, and to enhance penetration of other actives.
Glycyrrhiza Glabra (licorice) Root Extract is a botanical ingredient containing glycyrrhizin and glabridin, valued for its anti-inflammatory and skin-brightening properties. It is commonly used to calm irritation, reduce redness, and help fade hyperpigmentation by inhibiting tyrosinase activity.
Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations.
Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier.
Portulaca oleracea (purslane) extract is a plant-derived ingredient rich in omega-3 fatty acids, vitamins, and flavonoids used in topical formulations for its antioxidant, anti-inflammatory, and skin-soothing properties. It is commonly included to calm irritation and support skin barrier comfort.
Beta-glucan is a polysaccharide derived from sources such as oats, yeast, and mushrooms that functions as a humectant and skin-soothing ingredient. It supports hydration, helps reinforce the skin barrier, and has been studied for antioxidant and wound-healing properties.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Irritation or sensitivity | Very rare | Purified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water. |
| Transepidermal water loss aggravation in compromised skin | Rare | Evaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent. |
| Mild transient stinging or irritation | Uncommon | More likely on broken or compromised skin or at high concentrations. |
| Allergic contact dermatitis | Rare | Documented in patch-test studies but considered a relatively weak sensitizer. |
| Redness or itching | Rare | Typically resolves after discontinuation. |
| Mild skin irritation or redness | Uncommon | Transient localized reaction, typically at higher concentrations. |
| Itching or stinging on application | Uncommon | Usually mild and self-limiting. |
| Dryness or peeling | Rare | Generally well tolerated; dryness uncommon in topical use. |
| Redness or tingling | Rare | Typically resolves quickly after discontinuation |
| Mild contact irritation | Rare | Occasional redness or stinging, usually in sensitive or compromised skin. |
| Comedogenicity / clogged pores | Rare | Generally low comedogenic potential, but acne-prone individuals may occasionally react. |
| Mild skin irritation | Rare | Possible at higher concentrations, usually transient. |
| Enhanced penetration of other ingredients | Uncommon | By disrupting skin barrier it may slightly increase absorption of co-applied substances. |
| Contact irritation or mild redness | Uncommon | Generally well tolerated; mild stinging may occur in sensitive skin or at higher concentrations. |
| Cross-reactivity in those with plant/legume allergies | Very rare | Licorice belongs to the Fabaceae family; theoretical cross-sensitivity is rarely documented topically. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Aqua Solvent / vehicle | Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Dimethyl Sulfone Key active Skin conditioning / anti-inflammatory agent | Dimethyl sulfone (MSM, methylsulfonylmethane) is an organic sulfur compound used in topical formulations for its purported skin-conditioning, anti-inflammatory, and barrier-supporting properties. It is sometimes included to help improve skin tone, hydration, and to enhance penetration of other actives. |
| Betaine Humectant / osmolyte | Betaine is a naturally derived amino acid derivative (trimethylglycine) used in skincare as a humectant and osmoprotectant that attracts and retains moisture while helping stabilize skin barrier function. It also improves the texture and mildness of formulations. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Disodium EDTA Chelating agent | Disodium EDTA is a chelating agent used in cosmetics to bind metal ions, improving product stability, preventing rancidity, and enhancing the efficacy of preservatives. It is a formulation/base ingredient rather than a treatment active. |
| Glycyrrhiza Glabra Root Extract Key active Soothing / brightening agent | Glycyrrhiza Glabra (licorice) Root Extract is a botanical ingredient containing glycyrrhizin and glabridin, valued for its anti-inflammatory and skin-brightening properties. It is commonly used to calm irritation, reduce redness, and help fade hyperpigmentation by inhibiting tyrosinase activity. |
| Centella Asiatica Extract Key active Soothing/antioxidant active | Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations. |
| Chlorphenesin Preservative / antimicrobial | Chlorphenesin is a synthetic antimicrobial agent used in cosmetics and skincare as a preservative to inhibit the growth of bacteria, yeast, and mold. It is also occasionally used for its mild muscle-relaxant and antifungal properties in topical formulations. |
| Tocopheryl Acetate Key active Antioxidant | Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Arginine Amino acid / pH adjuster & conditioning agent | Arginine is a basic amino acid used in skincare primarily as a pH buffer/neutralizer and humectant-like conditioning agent that supports skin hydration and barrier function. It is generally well tolerated and often paired with acidic ingredients to balance formulation pH. |
| Carbomer Thickener / gelling agent | Carbomer is a synthetic high-molecular-weight polymer of acrylic acid used to thicken, stabilize, and control the viscosity of gels, creams, and lotions. It functions as a formulation aid rather than a therapeutic active. |
| Panthenol Humectant / skin-conditioning agent | Panthenol (provitamin B5) is converted to pantothenic acid in the skin, where it acts as a humectant and helps support skin barrier function and hydration. It is also used for its soothing and mild anti-inflammatory properties in topical formulations. |
| Luffa Cylindrica Fruit/Leaf/Stem Extract Skin conditioning/soothing botanical extract | Luffa Cylindrica Fruit/Leaf/Stem Extract is a plant-derived ingredient used in topical formulations primarily for skin-conditioning, soothing, and moisturizing support. It is generally regarded as a supportive botanical rather than a clinically established treatment active. |
| 1,2-Hexanediol Humectant / preservative booster | 1,2-Hexanediol is a synthetic diol used in skincare as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, often allowing reduced or preservative-free systems. It helps maintain product stability while contributing mild moisturizing properties. |
| Hydroxyethylcellulose Thickener/viscosity modifier | Hydroxyethylcellulose is a non-ionic, water-soluble cellulose derivative used to thicken, stabilize, and adjust the texture of aqueous cosmetic formulations. It functions as a gelling and film-forming agent rather than providing a direct biological skin benefit. |
| Aloe Barbadensis Leaf Extract Soothing/moisturizing agent | Aloe Barbadensis Leaf Extract is derived from the aloe vera plant and is used in skincare for its hydrating, soothing, and mild anti-inflammatory properties. It is commonly included as a supportive base ingredient rather than a primary treatment active. |
| Althaea Rosea Flower Extract Soothing/emollient botanical extract | Althaea Rosea (hollyhock) Flower Extract is a plant-derived ingredient used in cosmetics for its mucilage content, which provides soothing, moisturizing, and skin-conditioning properties. It is commonly included to help calm and hydrate the skin. |
| Portulaca Oleracea Extract Key active Antioxidant/soothing botanical extract | Portulaca oleracea (purslane) extract is a plant-derived ingredient rich in omega-3 fatty acids, vitamins, and flavonoids used in topical formulations for its antioxidant, anti-inflammatory, and skin-soothing properties. It is commonly included to calm irritation and support skin barrier comfort. |
| Polyquaternium-51 Humectant / moisturizer | Polyquaternium-51 (also known as Lipidure) is a synthetic phospholipid-mimicking polymer used in cosmetics to attract and bind water to the skin, enhancing hydration and providing a smooth, conditioned feel. It is valued for its strong moisture-retention and skin-compatibility, and is often included in moisturizers, serums, and hair care products. |
| Beta-Glucan Key active Hydrating soothing agent | Beta-glucan is a polysaccharide derived from sources such as oats, yeast, and mushrooms that functions as a humectant and skin-soothing ingredient. It supports hydration, helps reinforce the skin barrier, and has been studied for antioxidant and wound-healing properties. |
| Lysine HCl Conditioning/amino acid | Lysine HCl is the hydrochloride salt of the essential amino acid L-lysine, used in skincare primarily as a skin-conditioning and humectant agent that supports the skin's natural moisturizing factor and protein structure. It is generally considered a supportive formulation ingredient rather than a clinically proven active. |
| Sodium Ascorbyl Phosphate Key active Vitamin C derivative / antioxidant | Sodium Ascorbyl Phosphate is a stable, water-soluble derivative of vitamin C (ascorbic acid) that is converted to active ascorbic acid in the skin. It provides antioxidant protection, supports collagen synthesis, and is also studied for its brightening and anti-acne (antibacterial) effects. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Acetyl Methionine Key active Conditioning/antioxidant amino acid derivative | Acetyl Methionine is an acetylated form of the amino acid methionine used in skincare as a conditioning agent and antioxidant, supporting skin hydration and helping protect against oxidative stress. It is generally considered well tolerated in topical formulations. |
| Theanine Key active Antioxidant / soothing agent | Theanine (L-theanine) is an amino acid derived primarily from tea leaves, used in topical formulations for its antioxidant and skin-soothing properties. In skincare it is included to help mitigate oxidative stress and support a calming effect on the skin. |
| Proline Amino acid / skin-conditioning agent | Proline is a non-essential amino acid and a key component of collagen, used in skincare as a humectant and skin-conditioning agent to support hydration and the skin barrier. It is generally well tolerated and often included in formulations for its moisturizing and structural-protein-supporting properties. |
| Natto Gum Humectant/film-former | Natto gum is a polysaccharide-rich biopolymer (polyglutamic acid) derived from fermented soybeans (natto) that is used in skincare as a moisturizing humectant and film-forming agent. It helps attract and retain water in the stratum corneum, improving skin hydration and texture. |
| Disodium Phosphate Buffering/pH adjuster | Disodium Phosphate is an inorganic salt used in cosmetic and skincare formulations primarily as a buffering agent and pH adjuster. It helps stabilize product pH and acts as an emulsifying or sequestering aid in various topical preparations. |
| Polysorbate 60 Emulsifier / surfactant | Polysorbate 60 is a nonionic surfactant and emulsifier derived from sorbitol and stearic acid, used to blend oil and water phases and stabilize emulsions in creams and lotions. It functions as a formulation aid rather than a therapeutic active. |
| Sodium Phosphate pH buffer / emulsion stabilizer | Sodium phosphate is a salt used in skincare primarily as a buffering agent to maintain formula pH and as a sequestrant or emulsifier. It is considered a functional base ingredient rather than a treatment active. |
| Citrus Limon Peel Oil Fragrance/skin conditioning | Citrus Limon (lemon) Peel Oil is a volatile essential oil cold-pressed from lemon peel, used in cosmetics primarily as a fragrance and natural scenting agent. It contains limonene, citral, and other terpenes that contribute aroma but also account for its sensitizing and phototoxic potential. |
| Lavandula Angustifolia Oil Fragrance / botanical extract | Lavandula Angustifolia (lavender) oil is an essential oil distilled from lavender flowers, used in skincare primarily as a natural fragrance and for its purported soothing and antimicrobial properties. It is a complex mixture containing linalool and linalyl acetate, which contribute to both its scent and its allergenic potential. |
| Citrus Aurantium Dulcis Peel Oil Fragrance/flavoring agent | Citrus Aurantium Dulcis (sweet orange) Peel Oil is a cold-pressed essential oil from orange peel used primarily as a natural fragrance and masking agent in cosmetic formulations. It contains limonene as a major constituent along with other terpenes. |
| Pelargonium Graveolens Flower Oil Fragrance/aromatic oil | Pelargonium Graveolens Flower Oil (geranium oil) is an essential oil derived from geranium flowers, used in skincare primarily for its scent and as a botanical additive with mild antimicrobial and astringent properties. It is generally considered a fragrance/sensory ingredient rather than a proven treatment active. |
| Cananga Odorata Flower Oil Fragrance/aromatic oil | Cananga Odorata Flower Oil (ylang-ylang oil) is an essential oil distilled from the flowers of the Cananga odorata tree, used in cosmetics primarily as a fragrance and aromatic ingredient. It contains volatile aromatic compounds such as linalool, benzyl benzoate, and geranyl acetate. |
| Eucalyptus Globulus Leaf Oil Fragrance/essential oil (aromatic, antimicrobial) | Eucalyptus Globulus Leaf Oil is a volatile essential oil derived from eucalyptus leaves, rich in 1,8-cineole (eucalyptol), used in skincare for its aromatic, antimicrobial, and mildly soothing properties. It is most often added for scent or minor antiseptic effect rather than as a primary therapeutic active. |
| Copper Tripeptide-1 Key active Signal peptide / skin-conditioning agent | Copper Tripeptide-1 (GHK-Cu) is a copper-bound peptide used in skincare for its reported ability to support collagen and elastin synthesis, wound healing, and antioxidant activity. It is considered a bioactive cosmetic ingredient targeting signs of skin aging. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.