Below is every ingredient in The Derma Co. X Dr V Skin Renew Barrier Repair Peptide Moisturizer with Peptide & Vitamin C - 50g explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
3-O-Ethyl Ascorbic Acid is a stable, water-soluble ethylated derivative of vitamin C that converts to ascorbic acid in the skin, providing antioxidant protection and supporting collagen synthesis and pigmentation control. It is valued for greater stability than pure L-ascorbic acid while delivering similar brightening and anti-aging benefits.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Irritation or sensitivity | Very rare | Purified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water. |
| Transepidermal water loss aggravation in compromised skin | Rare | Evaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent. |
| Mild skin irritation | Uncommon | Transient stinging or redness, more likely on compromised or sensitive skin. |
| Allergic contact dermatitis | Rare | Sensitization is infrequent; propanediol is generally considered low-risk for allergy. |
| Enhanced penetration of co-formulated irritants | Uncommon | As a penetration enhancer it may increase absorption and irritation potential of other actives. |
| Contact allergy / sensitization | Very rare | Rarely implicated in allergic contact dermatitis; considered low sensitizing potential. |
| Comedogenicity / pore congestion | Rare | Low comedogenic rating, but acne-prone individuals may occasionally experience clogged pores. |
| Skin irritation | Rare | Mild redness or stinging occasionally reported; generally well tolerated. |
| Cross-reactivity with other fatty alcohols | Rare | Sensitized individuals may react to related fatty alcohols such as cetyl or stearyl alcohol alone. |
| Mild transient flushing or redness | Uncommon | More likely at higher concentrations or in sensitive skin; usually subsides quickly. |
| Tingling, stinging, or burning sensation | Uncommon | Often associated with higher percentages or compromised barrier. |
| Contact irritation or itching | Rare | Generally dose-dependent and resolves with discontinuation. |
| Mild transient stinging or irritation | Rare | Generally very well tolerated; minor irritation reported mostly on compromised skin |
| Redness or tingling | Rare | Typically resolves quickly after discontinuation |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Aqua Solvent / vehicle | Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery. |
| Propanediol Humectant/solvent | Propanediol is a plant-derived glycol used in skincare as a humectant, solvent, and penetration enhancer that improves moisturization and the spreadability of formulations. It also helps solubilize other ingredients and can boost the efficacy of certain actives. |
| Coco Caprylate/Caprate Emollient / skin-conditioning agent | Coco-Caprylate/Caprate is a lightweight ester emollient derived from coconut-sourced fatty alcohols and caprylic/capric acids, used to provide a smooth, dry, non-greasy skin feel and to act as a silicone alternative. It functions primarily as a spreading agent and texture enhancer in lotions, creams, and sunscreens. |
| Ceto Stearyl Alcohol Emollient / emulsifier | Cetostearyl alcohol is a fatty alcohol blend of cetyl and stearyl alcohols used in skincare and topical formulations as an emollient, emulsion stabilizer, and thickening agent. It helps maintain product texture and supports the skin barrier rather than acting as a therapeutic active. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Betaine Humectant / osmolyte | Betaine is a naturally derived amino acid derivative (trimethylglycine) used in skincare as a humectant and osmoprotectant that attracts and retains moisture while helping stabilize skin barrier function. It also improves the texture and mildness of formulations. |
| Cyclopentasiloxane Emollient/silicone | Cyclopentasiloxane is a volatile cyclic silicone widely used in skincare and cosmetics to impart a smooth, silky feel and spreadability before evaporating, leaving no greasy residue. It also serves as a carrier and helps reduce tackiness in formulations. |
| Neopentyl Glycol Diheptanoate Emollient | Neopentyl Glycol Diheptanoate is a synthetic diester emollient used in skincare and cosmetics to provide a light, non-greasy skin feel and to soften and smooth the skin. It functions as a base/texture ingredient rather than a treatment active. |
| Isododecane Emollient/solvent | Isododecane is a lightweight, volatile branched-chain hydrocarbon used as a solvent and emollient in cosmetics. It spreads easily and evaporates quickly, improving texture and wear in products like long-lasting makeup, primers, and sunscreens. |
| Squalane Emollient / occlusive moisturizer | Squalane is a saturated, stable hydrocarbon derived from squalene (sourced from plants like olives or sugarcane, or shark liver) used as a lightweight emollient that softens skin and reinforces the skin barrier by reducing transepidermal water loss. It is well tolerated, non-comedogenic for most users, and serves as a base or carrier ingredient rather than a therapeutic active. |
| 3-O-Ethyl Ascorbic Acid Key active Antioxidant / brightening vitamin C derivative | 3-O-Ethyl Ascorbic Acid is a stable, water-soluble ethylated derivative of vitamin C that converts to ascorbic acid in the skin, providing antioxidant protection and supporting collagen synthesis and pigmentation control. It is valued for greater stability than pure L-ascorbic acid while delivering similar brightening and anti-aging benefits. |
| Ceramide N Skin barrier repair / moisturizer | Ceramide N (also known as ceramide NP or ceramide 3) is a lipid that naturally occurs in the stratum corneum and helps restore and maintain the skin's barrier function and hydration. It is commonly used in moisturizers and barrier-repair formulations to reduce transepidermal water loss. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.