Below is every ingredient in Clarins Multi Active Night Comfort Cream 50Ml explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier.
Actinidia Chinensis (Kiwi) Fruit Extract is derived from the kiwi fruit and is used in skincare for its antioxidant properties, attributed to vitamin C, polyphenols, and other phytonutrients. It functions as a skin-conditioning agent and may help protect against oxidative stress.
Diospyros Mespiliformis Leaf Extract is a plant-derived ingredient obtained from the African ebony (jackalberry) tree, valued in skincare for its antioxidant and phenolic content thought to help counter oxidative stress. It is used in formulations as a botanical conditioning and protective agent.
Glycolic acid is an alpha-hydroxy acid derived from sugar cane that exfoliates by loosening bonds between dead skin cells on the surface, promoting cell turnover and improving texture, tone, and fine lines. It is one of the smallest AHAs, allowing relatively deep penetration into the skin.
Lactic acid is an alpha-hydroxy acid that exfoliates the skin by loosening bonds between corneocytes, promoting cell turnover, and acting as a humectant to improve hydration, texture, and tone. It is commonly used at concentrations ranging from low (hydration) to higher peel-strength formulations.
Copper Palmitoyl Heptapeptide-14 is a copper-bound, lipidized peptide used in anti-aging formulations to support collagen and extracellular matrix synthesis and improve skin firmness. It combines copper's role in tissue repair with a peptide carrier intended to enhance signaling and skin penetration.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Skin irritation or mild stinging | Rare | Generally well tolerated; occasional reports in sensitive skin. |
| Allergic contact dermatitis | Very rare | Isolated case reports; the ingredient has low sensitizing potential. |
| Comedogenicity (pore clogging) | Uncommon | May contribute to breakouts in acne-prone individuals depending on concentration and formulation. |
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
| Skin irritation | Rare | Generally well tolerated; mild irritation reported infrequently in sensitive individuals. |
| Comedogenicity (clogged pores) | Rare | Considered low to non-comedogenic, but possible in acne-prone skin depending on formulation. |
| Mild skin irritation | Uncommon | Transient stinging or redness, more likely on compromised or sensitive skin. |
| Enhanced penetration of co-formulated irritants | Uncommon | As a penetration enhancer it may increase absorption and irritation potential of other actives. |
| Mild skin irritation or redness | Rare | Generally considered non-irritating; occasional mild reactions reported. |
| Clogged pores / comedogenic-related breakouts | Uncommon | Often anecdotal; dimethicone is largely regarded as non-comedogenic but may trap debris if skin is not cleansed well. |
| Eye irritation on accidental contact | Rare | Transient stinging or discomfort if product enters the eyes. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Cetearyl Isononanoate Emollient/skin-conditioning agent | Cetearyl Isononanoate is an ester of cetearyl alcohol and isononanoic acid used as an emollient and emulsion stabilizer that imparts a smooth, non-greasy skin feel and improves spreadability in creams and lotions. It functions as a formulation/texture ingredient rather than a therapeutic active. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Isononyl Isononanoate Emollient/skin-conditioning agent | Isononyl Isononanoate is a synthetic ester emollient used in cosmetics to impart a light, silky, non-greasy skin feel and to aid the spreadability of formulations. It functions as a base/texture ingredient rather than a treatment active. |
| Propanediol Humectant/solvent | Propanediol is a plant-derived glycol used in skincare as a humectant, solvent, and penetration enhancer that improves moisturization and the spreadability of formulations. It also helps solubilize other ingredients and can boost the efficacy of certain actives. |
| Dimethicone Emollient/occlusive (silicone) | Dimethicone is a silicone-based polymer used in skincare to soften skin, smooth texture, and form a breathable protective barrier that reduces transepidermal water loss. It is widely used as a base/formulation ingredient rather than a therapeutic active. |
| Cetearyl Alcohol Emollient/emulsifier | Cetearyl alcohol is a fatty alcohol blend (cetyl and stearyl alcohol) used in skincare as an emollient, emulsion stabilizer, and thickening agent. It helps soften skin and keep oil and water phases blended in creams and lotions. |
| Butyrospermum Parkii (Shea) Butter Emollient / occlusive moisturizer | Butyrospermum Parkii (Shea) Butter is a plant-derived fat extracted from the nuts of the African shea tree, rich in triglycerides and unsaponifiables. It is widely used in skincare to soften, smooth, and condition the skin while forming an occlusive barrier that reduces water loss. |
| Glyceryl Stearate Emulsifier/emollient | Glyceryl Stearate is a glycerol ester of stearic acid widely used as a non-ionic emulsifier and emollient to stabilize oil-in-water formulations and improve skin feel. It functions as a base/formulation ingredient rather than a therapeutic active. |
| Peg-100 Stearate Emulsifier/surfactant | PEG-100 Stearate is a polyethylene glycol ester of stearic acid used as a nonionic surfactant and emulsifier to stabilize oil-in-water formulations and improve skin feel. It functions as a formulation base ingredient rather than a therapeutic active. |
| Cetearyl Glucoside Emulsifier | Cetearyl Glucoside is a plant-derived (glucose and fatty alcohol) nonionic emulsifier used to blend oil and water phases and stabilize creams and lotions. It is valued for being mild and well-tolerated in cosmetic formulations. |
| Fragrance Fragrance/masking agent | Fragrance refers to a blend of natural or synthetic aromatic compounds added to skincare products to impart a pleasant scent or mask the odor of other ingredients. It serves a sensory and formulation purpose rather than a therapeutic one. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Cellulose Thickener / absorbent / texturizer | Cellulose is a plant-derived polysaccharide used in skincare as a thickening, stabilizing, and absorbent agent, and in exfoliant or film-forming roles. It is generally inert and well tolerated as a formulation base ingredient. |
| Dipsacus Sylvestris Extract Botanical extract / skin-conditioning agent | Dipsacus Sylvestris (wild teasel) extract is a plant-derived ingredient used in skincare for its purported conditioning, soothing, and antioxidant properties. It is typically included to support skin hydration and overall skin appearance. |
| Carbomer Thickener / gelling agent | Carbomer is a synthetic high-molecular-weight polymer of acrylic acid used to thicken, stabilize, and control the viscosity of gels, creams, and lotions. It functions as a formulation aid rather than a therapeutic active. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Tocopheryl Acetate Key active Antioxidant | Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier. |
| Tromethamine pH adjuster / buffering agent | Tromethamine (trometamol, TRIS) is an organic amine base used in cosmetic and topical formulations to neutralize acidic components and stabilize pH. It functions primarily as a buffering and neutralizing agent rather than as a therapeutic active. |
| Disodium Edta Chelating agent | Disodium EDTA is a chelating agent used in cosmetics to bind metal ions, improving product stability, preventing rancidity, and enhancing the efficacy of preservatives. It is a formulation/base ingredient rather than a treatment active. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Alcohol Solvent / penetration enhancer | Alcohol (typically ethanol or denatured alcohol) is used in skincare as a solvent, antimicrobial agent, and to improve product spreadability and rapid drying. It also enhances penetration of other ingredients and gives a lightweight feel to formulations. |
| Eschscholzia Californica Flower/Leaf/Stem Extract Soothing/antioxidant botanical extract | Eschscholzia Californica (California poppy) flower/leaf/stem extract is used in skincare for its purported soothing, antioxidant, and skin-conditioning properties. It is typically included as a botanical additive rather than a primary treatment active. |
| Actinidia Chinensis (Kiwi) Fruit Extract Key active Antioxidant/Skin-conditioning | Actinidia Chinensis (Kiwi) Fruit Extract is derived from the kiwi fruit and is used in skincare for its antioxidant properties, attributed to vitamin C, polyphenols, and other phytonutrients. It functions as a skin-conditioning agent and may help protect against oxidative stress. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Diospyros Mespiliformis Leaf Extract Key active Antioxidant / botanical extract | Diospyros Mespiliformis Leaf Extract is a plant-derived ingredient obtained from the African ebony (jackalberry) tree, valued in skincare for its antioxidant and phenolic content thought to help counter oxidative stress. It is used in formulations as a botanical conditioning and protective agent. |
| Maltodextrin Carrier/film-forming agent | Maltodextrin is a polysaccharide derived from starch hydrolysis, used in skincare primarily as a carrier, bulking agent, film former, and stabilizer for active ingredients and powders. It also helps improve texture and can act as a mild thickening or emulsion-stabilizing aid. |
| Sanicula Europaea Extract Soothing/antioxidant botanical extract | Sanicula Europaea (wood sanicle) extract is a plant-derived ingredient used in skincare for its purported soothing, antioxidant, and skin-conditioning properties, attributed to constituents such as tannins, saponins, and flavonoids. It is most often included as a supporting botanical rather than a primary active. |
| Lapsana Communis Flower/Leaf/Stem Extract Botanical extract / skin conditioning | Lapsana Communis (nipplewort) Flower/Leaf/Stem Extract is a plant-derived ingredient used in skincare primarily as a skin-conditioning and soothing agent, traditionally associated with mild emollient and skin-calming properties. It functions mainly as a supportive botanical rather than a clinically proven treatment active. |
| Furcellaria Lumbricalis Extract Marine algae extract / film-forming hydrator | Furcellaria Lumbricalis Extract is derived from a red seaweed and is used in skincare primarily as a hydrating, film-forming and texturizing agent due to its polysaccharide (carrageenan-like) content. It provides skin conditioning, moisture retention and a smoothing surface feel. |
| Sodium Citrate pH adjuster / chelating agent | Sodium citrate is the sodium salt of citric acid used in skincare primarily as a buffering agent to stabilize formulation pH and as a chelator that binds metal ions to improve product stability. It is a base/formulation ingredient rather than a therapeutic active. |
| Potassium Sorbate Preservative | Potassium sorbate is the potassium salt of sorbic acid, used as a mild preservative to inhibit mold, yeast, and some bacterial growth in cosmetic formulations. It is most effective at acidic pH and is often combined with other preservatives for broad-spectrum protection. |
| Citric Acid pH adjuster / AHA exfoliant | Citric acid is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formulation pH and as a chelating agent, and at higher concentrations as a mild chemical exfoliant. It can promote surface cell turnover and is sometimes included in antioxidant or brightening products. |
| Glycolic Acid Key active Chemical exfoliant (AHA) | Glycolic acid is an alpha-hydroxy acid derived from sugar cane that exfoliates by loosening bonds between dead skin cells on the surface, promoting cell turnover and improving texture, tone, and fine lines. It is one of the smallest AHAs, allowing relatively deep penetration into the skin. |
| Lactic Acid Key active Chemical exfoliant (AHA) | Lactic acid is an alpha-hydroxy acid that exfoliates the skin by loosening bonds between corneocytes, promoting cell turnover, and acting as a humectant to improve hydration, texture, and tone. It is commonly used at concentrations ranging from low (hydration) to higher peel-strength formulations. |
| Maris Sal/Sea Salt/Sea Salt Exfoliant/Texturizing agent | Maris Sal (sea salt) is a naturally derived mineral used in skincare as a thickening, exfoliating, and bulking agent, and to influence the viscosity and texture of formulations. It can also provide mild mineral content and act as a scrub particle in body and bath products. |
| Polyvinyl Alcohol Film-forming agent / viscosity modifier | Polyvinyl alcohol (PVA) is a synthetic, water-soluble polymer commonly used in peel-off masks and as a film-forming, thickening, and binding agent in cosmetic formulations. It dries to form a flexible film on the skin that can be peeled away, often used for texture and adhesive properties rather than therapeutic effect. |
| Copper Palmitoyl Heptapeptide-14 Key active Signal peptide / copper-complex skin-conditioning agent | Copper Palmitoyl Heptapeptide-14 is a copper-bound, lipidized peptide used in anti-aging formulations to support collagen and extracellular matrix synthesis and improve skin firmness. It combines copper's role in tissue repair with a peptide carrier intended to enhance signaling and skin penetration. |
| Heptapeptide-15 Palmitate Key active Signal peptide / skin-conditioning agent | Heptapeptide-15 Palmitate is a palmitoylated synthetic seven-amino-acid peptide used in cosmetics to support skin barrier and reduce visible signs of inflammation or aging. The palmitic acid chain improves lipid solubility and skin penetration of the peptide. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.