Below is every ingredient in Fixderma 17 Vitamin C Face Serum With Retinol 10 Ml explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Ascorbyl Methylsilanol Pectinate is a stabilized vitamin C derivative combining ascorbic acid with an organosilicon (silanol) and pectin carrier, used in skincare for antioxidant protection and to support collagen synthesis and skin brightening. The silanol and pectin components are intended to improve stability and skin delivery compared to pure ascorbic acid.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Tocopheryl acetate is a stable, esterified form of vitamin E (vitamin E acetate) widely used in skincare for its antioxidant properties. Once absorbed, it is converted to active tocopherol, helping protect skin from oxidative stress and supporting the skin barrier.
Lactobionic acid is a polyhydroxy acid derived from lactose that gently exfoliates the skin surface while attracting and binding water. It also offers humectant and antioxidant properties and is generally well tolerated, including by sensitive skin.
Ferulic acid is a plant-derived phenolic antioxidant that neutralizes free radicals and helps protect skin from UV-induced oxidative damage. It is frequently combined with vitamins C and E to enhance their stability and photoprotective effect.
Cysteine is a sulfur-containing amino acid used in skincare and haircare for its antioxidant properties and its role in supporting keratin and glutathione synthesis. It is also employed in hair straightening and perming formulations to reduce disulfide bonds.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild skin irritation or stinging | Uncommon | Transient, more likely on sensitive or compromised skin |
| Erythema (redness) | Rare | Usually mild and self-resolving |
| Allergic contact dermatitis | Very rare | Isolated hypersensitivity reactions possible |
| Dryness or peeling | Rare | Typically related to formulation rather than the ingredient itself |
| Mild transient flushing or redness | Uncommon | More likely at higher concentrations or in sensitive skin; usually subsides quickly. |
| Tingling, stinging, or burning sensation | Uncommon | Often associated with higher percentages or compromised barrier. |
| Contact irritation or itching | Rare | Generally dose-dependent and resolves with discontinuation. |
| Skin irritation or stinging | Uncommon | Mild transient irritation may occur, particularly at higher concentrations. |
| Contact urticaria | Rare | Hive-like immediate reactions reported in isolated cases. |
| Folliculitis or acneiform breakouts | Rare | May occur in some users, especially in heavy or occlusive formulations. |
| Skin irritation | Rare | Mild transient redness or stinging, usually formulation-dependent. |
| Mild transient stinging or tingling | Common | Brief sensation on application, especially at higher concentrations |
| Skin redness or irritation | Uncommon | More likely with frequent use or compromised skin barrier |
| Increased photosensitivity | Rare | PHAs cause less sun sensitivity than AHAs, but sunscreen use is advised |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Ascorbyl Methylsilanol Pectinate Key active Antioxidant / Vitamin C derivative | Ascorbyl Methylsilanol Pectinate is a stabilized vitamin C derivative combining ascorbic acid with an organosilicon (silanol) and pectin carrier, used in skincare for antioxidant protection and to support collagen synthesis and skin brightening. The silanol and pectin components are intended to improve stability and skin delivery compared to pure ascorbic acid. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Tocoplieryl Acetate Key active Antioxidant | Tocopheryl acetate is a stable, esterified form of vitamin E (vitamin E acetate) widely used in skincare for its antioxidant properties. Once absorbed, it is converted to active tocopherol, helping protect skin from oxidative stress and supporting the skin barrier. |
| Hydroxyethylcellulose Thickener/viscosity modifier | Hydroxyethylcellulose is a non-ionic, water-soluble cellulose derivative used to thicken, stabilize, and adjust the texture of aqueous cosmetic formulations. It functions as a gelling and film-forming agent rather than providing a direct biological skin benefit. |
| Lactobionic Acid Key active Polyhydroxy acid (PHA) exfoliant/humectant | Lactobionic acid is a polyhydroxy acid derived from lactose that gently exfoliates the skin surface while attracting and binding water. It also offers humectant and antioxidant properties and is generally well tolerated, including by sensitive skin. |
| Hydrolysed Hyaluronic Acid Humectant / skin-conditioning agent | Hydrolysed hyaluronic acid is a low-molecular-weight, enzymatically fragmented form of hyaluronic acid used in skincare to attract and bind water, providing surface and superficial hydration. Its smaller size allows somewhat better penetration into the upper layers of the epidermis compared with high-molecular-weight hyaluronic acid. |
| Macadamia Integrifolia Seed Oil Emollient / skin-conditioning oil | Macadamia Integrifolia Seed Oil is a plant-derived emollient rich in oleic and palmitoleic fatty acids, used to soften, condition, and provide occlusive moisturization to the skin. It functions as a base/carrier ingredient rather than a targeted treatment active. |
| Ferulic Acid Key active Antioxidant | Ferulic acid is a plant-derived phenolic antioxidant that neutralizes free radicals and helps protect skin from UV-induced oxidative damage. It is frequently combined with vitamins C and E to enhance their stability and photoprotective effect. |
| Fragrance Fragrance/masking agent | Fragrance refers to a blend of natural or synthetic aromatic compounds added to skincare products to impart a pleasant scent or mask the odor of other ingredients. It serves a sensory and formulation purpose rather than a therapeutic one. |
| Cysteine Key active Antioxidant / amino acid conditioning agent | Cysteine is a sulfur-containing amino acid used in skincare and haircare for its antioxidant properties and its role in supporting keratin and glutathione synthesis. It is also employed in hair straightening and perming formulations to reduce disulfide bonds. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.