Below is every ingredient in Klairs Supple Preparation Facial Toner 30Ml explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Dimethyl sulfone (MSM, methylsulfonylmethane) is an organic sulfur compound used in topical formulations for its purported skin-conditioning, anti-inflammatory, and barrier-supporting properties. It is sometimes included to help improve skin tone, hydration, and to enhance penetration of other actives.
Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations.
Licorice root extract is a botanical ingredient valued in skincare for its skin-brightening and soothing properties, primarily attributed to compounds such as glabridin and liquiritin. It is used to help reduce hyperpigmentation, calm inflammation, and provide antioxidant protection.
Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier.
Beta-glucan is a polysaccharide derived from sources such as oats, yeast, and mushrooms that functions as a humectant and skin-soothing ingredient. It supports hydration, helps reinforce the skin barrier, and has been studied for antioxidant and wound-healing properties.
Portulaca (Portulaca oleracea, purslane) extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and soothing properties, attributed to compounds like omega-3 fatty acids, flavonoids, and vitamins. It is commonly added to formulations aimed at calming irritated or sensitive skin.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient stinging or irritation | Uncommon | More likely on broken or compromised skin or at high concentrations. |
| Allergic contact dermatitis | Rare | Documented in patch-test studies but considered a relatively weak sensitizer. |
| Redness or itching | Rare | Typically resolves after discontinuation. |
| Mild skin irritation or redness | Uncommon | Transient localized reaction, typically at higher concentrations. |
| Itching or stinging on application | Uncommon | Usually mild and self-limiting. |
| Dryness or peeling | Rare | Generally well tolerated; dryness uncommon in topical use. |
| Redness or tingling | Rare | Typically resolves quickly after discontinuation |
| Mild contact irritation | Rare | Occasional redness or stinging, usually in sensitive or compromised skin. |
| Comedogenicity / clogged pores | Rare | Generally low comedogenic potential, but acne-prone individuals may occasionally react. |
| Contact irritation (redness, mild stinging) | Rare | Generally well tolerated; mild transient irritation possible in sensitive skin. |
| Acneiform breakouts | Rare | Occasional reports in acne-prone users with occlusive film-forming formulations. |
| Redness or dryness in low-humidity environments | Uncommon | Can draw moisture from skin if ambient humidity is very low and not sealed with an occlusive. |
| Hypersensitivity reactions with injectable forms | Very rare | Relevant mainly to dermal filler use, not topical cosmetic application. |
| Mild skin irritation | Rare | Possible at higher concentrations, usually transient. |
| Enhanced penetration of other ingredients | Uncommon | By disrupting skin barrier it may slightly increase absorption of co-applied substances. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Dimethyl Sulfone Key active Skin conditioning / anti-inflammatory agent | Dimethyl sulfone (MSM, methylsulfonylmethane) is an organic sulfur compound used in topical formulations for its purported skin-conditioning, anti-inflammatory, and barrier-supporting properties. It is sometimes included to help improve skin tone, hydration, and to enhance penetration of other actives. |
| Betaine Humectant / osmolyte | Betaine is a naturally derived amino acid derivative (trimethylglycine) used in skincare as a humectant and osmoprotectant that attracts and retains moisture while helping stabilize skin barrier function. It also improves the texture and mildness of formulations. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Natto Gum Humectant/film-former | Natto gum is a polysaccharide-rich biopolymer (polyglutamic acid) derived from fermented soybeans (natto) that is used in skincare as a moisturizing humectant and film-forming agent. It helps attract and retain water in the stratum corneum, improving skin hydration and texture. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Disodium Edta Chelating agent | Disodium EDTA is a chelating agent used in cosmetics to bind metal ions, improving product stability, preventing rancidity, and enhancing the efficacy of preservatives. It is a formulation/base ingredient rather than a treatment active. |
| Centella Asiatica Extract Key active Soothing/antioxidant active | Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations. |
| Glycyrrhiza Glabra (Licorice) Root Extract Key active Brightening / anti-inflammatory antioxidant | Licorice root extract is a botanical ingredient valued in skincare for its skin-brightening and soothing properties, primarily attributed to compounds such as glabridin and liquiritin. It is used to help reduce hyperpigmentation, calm inflammation, and provide antioxidant protection. |
| Polyquaternium-51 Humectant / moisturizer | Polyquaternium-51 (also known as Lipidure) is a synthetic phospholipid-mimicking polymer used in cosmetics to attract and bind water to the skin, enhancing hydration and providing a smooth, conditioned feel. It is valued for its strong moisture-retention and skin-compatibility, and is often included in moisturizers, serums, and hair care products. |
| Chlorphenesin Preservative / antimicrobial | Chlorphenesin is a synthetic antimicrobial agent used in cosmetics and skincare as a preservative to inhibit the growth of bacteria, yeast, and mold. It is also occasionally used for its mild muscle-relaxant and antifungal properties in topical formulations. |
| Tocopheryl Acetate Key active Antioxidant | Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier. |
| Carbomer Thickener / gelling agent | Carbomer is a synthetic high-molecular-weight polymer of acrylic acid used to thicken, stabilize, and control the viscosity of gels, creams, and lotions. It functions as a formulation aid rather than a therapeutic active. |
| Panthenol Humectant / skin-conditioning agent | Panthenol (provitamin B5) is converted to pantothenic acid in the skin, where it acts as a humectant and helps support skin barrier function and hydration. It is also used for its soothing and mild anti-inflammatory properties in topical formulations. |
| Arginine Amino acid / pH adjuster & conditioning agent | Arginine is a basic amino acid used in skincare primarily as a pH buffer/neutralizer and humectant-like conditioning agent that supports skin hydration and barrier function. It is generally well tolerated and often paired with acidic ingredients to balance formulation pH. |
| Luffa Cylindrica Fruit/Leaf/Stem Extract Skin conditioning/soothing botanical extract | Luffa Cylindrica Fruit/Leaf/Stem Extract is a plant-derived ingredient used in topical formulations primarily for skin-conditioning, soothing, and moisturizing support. It is generally regarded as a supportive botanical rather than a clinically established treatment active. |
| Beta-Glucan Key active Hydrating soothing agent | Beta-glucan is a polysaccharide derived from sources such as oats, yeast, and mushrooms that functions as a humectant and skin-soothing ingredient. It supports hydration, helps reinforce the skin barrier, and has been studied for antioxidant and wound-healing properties. |
| Althaea Rosea Flower Extract Soothing/emollient botanical extract | Althaea Rosea (hollyhock) Flower Extract is a plant-derived ingredient used in cosmetics for its mucilage content, which provides soothing, moisturizing, and skin-conditioning properties. It is commonly included to help calm and hydrate the skin. |
| Aloe Barbadensis Leaf Extract Soothing/moisturizing agent | Aloe Barbadensis Leaf Extract is derived from the aloe vera plant and is used in skincare for its hydrating, soothing, and mild anti-inflammatory properties. It is commonly included as a supportive base ingredient rather than a primary treatment active. |
| Hydroxyethylcellulose Thickener/viscosity modifier | Hydroxyethylcellulose is a non-ionic, water-soluble cellulose derivative used to thicken, stabilize, and adjust the texture of aqueous cosmetic formulations. It functions as a gelling and film-forming agent rather than providing a direct biological skin benefit. |
| Portulaca Key active Soothing/antioxidant botanical extract | Portulaca (Portulaca oleracea, purslane) extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and soothing properties, attributed to compounds like omega-3 fatty acids, flavonoids, and vitamins. It is commonly added to formulations aimed at calming irritated or sensitive skin. |
| Oleracea Extract Key active Antioxidant / soothing botanical extract | Oleracea Extract (commonly derived from Portulaca oleracea, purslane) is a plant-derived ingredient rich in omega-3 fatty acids, vitamins, and antioxidants used in skincare for its soothing, anti-inflammatory, and antioxidant properties. It is often included to calm irritation and support skin barrier comfort. |
| Lysine Hcl Conditioning/amino acid | Lysine HCl is the hydrochloride salt of the essential amino acid L-lysine, used in skincare primarily as a skin-conditioning and humectant agent that supports the skin's natural moisturizing factor and protein structure. It is generally considered a supportive formulation ingredient rather than a clinically proven active. |
| Proline Amino acid / skin-conditioning agent | Proline is a non-essential amino acid and a key component of collagen, used in skincare as a humectant and skin-conditioning agent to support hydration and the skin barrier. It is generally well tolerated and often included in formulations for its moisturizing and structural-protein-supporting properties. |
| Sodium Ascorbyl Phosphate Key active Vitamin C derivative / antioxidant | Sodium Ascorbyl Phosphate is a stable, water-soluble derivative of vitamin C (ascorbic acid) that is converted to active ascorbic acid in the skin. It provides antioxidant protection, supports collagen synthesis, and is also studied for its brightening and anti-acne (antibacterial) effects. |
| Acetyl Methionine Key active Conditioning/antioxidant amino acid derivative | Acetyl Methionine is an acetylated form of the amino acid methionine used in skincare as a conditioning agent and antioxidant, supporting skin hydration and helping protect against oxidative stress. It is generally considered well tolerated in topical formulations. |
| Theanine Key active Antioxidant / soothing agent | Theanine (L-theanine) is an amino acid derived primarily from tea leaves, used in topical formulations for its antioxidant and skin-soothing properties. In skincare it is included to help mitigate oxidative stress and support a calming effect on the skin. |
| Copper Tripeptide-1 Key active Signal peptide / skin-conditioning agent | Copper Tripeptide-1 (GHK-Cu) is a copper-bound peptide used in skincare for its reported ability to support collagen and elastin synthesis, wound healing, and antioxidant activity. It is considered a bioactive cosmetic ingredient targeting signs of skin aging. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.