Below is every ingredient in Neutrogena Hydro Boost Hyaluronic Acid Water Gel Refill 50 G explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Urea is a naturally occurring component of the skin's natural moisturizing factor that hydrates by attracting and retaining water; at higher concentrations it also softens and exfoliates thickened or scaly skin. It is widely used to treat dry skin conditions such as xerosis, ichthyosis, and hyperkeratosis.
Allantoin is a naturally derived or synthetically produced compound used in skincare for its soothing, moisturizing, and keratolytic (skin-softening) properties. It promotes cell proliferation and helps calm irritation, commonly appearing in creams, lotions, and after-sun products.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
| Mild skin irritation or redness | Rare | Generally considered non-irritating; occasional mild reactions reported. |
| Clogged pores / comedogenic-related breakouts | Uncommon | Often anecdotal; dimethicone is largely regarded as non-comedogenic but may trap debris if skin is not cleansed well. |
| Allergic contact dermatitis | Very rare | True silicone allergy is exceptionally uncommon. |
| Eye irritation on accidental contact | Rare | Transient stinging or discomfort if product enters the eyes. |
| Mild skin irritation | Rare | Occasional transient redness or stinging, mainly in sensitive skin. |
| Comedogenicity / clogged pores | Rare | Low comedogenic potential, but possible in acne-prone individuals. |
| Comedogenic reaction | Rare | Possible pore congestion in acne-prone individuals depending on overall formulation. |
| Mild transient skin irritation | Rare | Occasional redness or stinging, typically in sensitive or compromised skin. |
| Subjective tackiness or film buildup | Uncommon | Cosmetic discomfort rather than a true adverse health effect. |
| Redness or tingling | Rare | Typically resolves quickly after discontinuation |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Dimethicone Emollient/occlusive (silicone) | Dimethicone is a silicone-based polymer used in skincare to soften skin, smooth texture, and form a breathable protective barrier that reduces transepidermal water loss. It is widely used as a base/formulation ingredient rather than a therapeutic active. |
| Cetearyl Olivate Emulsifier / emollient | Cetearyl Olivate is an olive oil-derived emulsifier and emollient, typically used with Sorbitan Olivate, that helps blend oil and water phases while conditioning and softening the skin. It supports the skin barrier and gives formulations a light, non-greasy feel. |
| Sorbitan Olivate Emulsifier | Sorbitan Olivate is an olive-derived ester of sorbitol and olive oil fatty acids used as a non-ionic emulsifier and emollient. It is often paired with Cetearyl Olivate (as Olivem 1000) to stabilize oil-in-water emulsions and impart a soft skin feel. |
| Polyacrylate Crosspolymer-6 Film-forming/sensory-enhancing rheology modifier | Polyacrylate Crosspolymer-6 is a synthetic crosslinked acrylate polymer used in skincare and cosmetic formulations to provide a smooth, silky sensory feel, stabilize emulsions, and help form a light film on the skin. It is a formulation aid rather than a biologically active treatment ingredient. |
| Betaine Humectant / osmolyte | Betaine is a naturally derived amino acid derivative (trimethylglycine) used in skincare as a humectant and osmoprotectant that attracts and retains moisture while helping stabilize skin barrier function. It also improves the texture and mildness of formulations. |
| Caprylyl Glycol Humectant / skin-conditioning agent and preservative booster | Caprylyl glycol is a multifunctional emollient and humectant derived from caprylic acid that helps hydrate skin and enhance the efficacy of preservatives in formulations. It is widely used as a stabilizing and conditioning base ingredient rather than a therapeutic active. |
| Synthetic Beeswax Emollient / thickener | Synthetic beeswax is a lab-produced wax composed of esters, fatty acids, and hydrocarbons that mimics natural beeswax. It functions as an emollient, thickening agent, and emulsion stabilizer in creams, balms, and lipsticks. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Pentylene Glycol Humectant / solvent / preservative-booster | Pentylene glycol is a glycol used in cosmetics as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, helping reduce reliance on traditional preservatives. It improves skin hydration and aids the delivery and stability of other ingredients. |
| Sodium Pca Humectant | Sodium PCA (sodium pyrrolidone carboxylic acid) is the sodium salt of pyroglutamic acid and a component of the skin's natural moisturizing factor (NMF). It is widely used in cosmetics as a water-binding humectant to hydrate and soften the skin. |
| Fructose Humectant | Fructose is a simple monosaccharide sugar used in skincare primarily as a humectant that attracts and binds water to help maintain skin hydration. It is generally considered a supporting/base ingredient rather than a therapeutic active. |
| Dimethicone Crosspolymer Silicone-based texture enhancer/film former | Dimethicone Crosspolymer is a crosslinked silicone polymer used in skincare and cosmetics to provide a smooth, silky feel, absorb excess oil, blur the appearance of pores and fine lines, and improve product spreadability. It functions as a formulation ingredient rather than a therapeutic active. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Dimethiconol Emollient/silicone conditioning agent | Dimethiconol is a silicone-based polymer used in skincare and haircare to provide smoothing, conditioning, and a soft, non-greasy emollient feel. It forms a thin, breathable film that reduces moisture loss and improves spreadability of formulations. |
| Sodium Lactate Humectant / NMF component | Sodium lactate is the sodium salt of lactic acid and a key component of skin's natural moisturizing factor (NMF), used to hydrate the skin and buffer formulation pH. It also has mild exfoliating and humectant properties that help maintain skin moisture and barrier function. |
| Urea Key active Humectant / keratolytic | Urea is a naturally occurring component of the skin's natural moisturizing factor that hydrates by attracting and retaining water; at higher concentrations it also softens and exfoliates thickened or scaly skin. It is widely used to treat dry skin conditions such as xerosis, ichthyosis, and hyperkeratosis. |
| Citric Acid pH adjuster / AHA exfoliant | Citric acid is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formulation pH and as a chelating agent, and at higher concentrations as a mild chemical exfoliant. It can promote surface cell turnover and is sometimes included in antioxidant or brightening products. |
| Pca Humectant / NMF component | PCA (pyrrolidone carboxylic acid), often as sodium PCA, is a naturally occurring component of skin's natural moisturizing factor (NMF) that attracts and binds water to the stratum corneum. It is used in skincare to improve hydration and skin softness. |
| Fragrance Fragrance/masking agent | Fragrance refers to a blend of natural or synthetic aromatic compounds added to skincare products to impart a pleasant scent or mask the odor of other ingredients. It serves a sensory and formulation purpose rather than a therapeutic one. |
| Sodium Hydroxide pH adjuster | Sodium hydroxide (lye) is a strong alkaline compound used in small amounts to adjust and stabilize the pH of cosmetic formulations. At regulated low concentrations in finished products it is considered safe, though it is corrosive in concentrated form. |
| Maltose Humectant / skin-conditioning agent | Maltose is a disaccharide sugar used in skincare primarily as a humectant and skin-conditioning agent, helping to attract and retain moisture in the stratum corneum. It is generally considered a low-risk, well-tolerated formulation ingredient rather than a therapeutic active. |
| Serine Humectant / amino acid | Serine is a naturally occurring amino acid and component of the skin's natural moisturizing factor (NMF), used in skincare to support hydration and help maintain the skin barrier. It is typically incorporated as a conditioning and water-binding agent rather than a clinical treatment active. |
| Alanine Amino acid / humectant | Alanine is a small non-essential amino acid used in skincare as a humectant and component of the skin's natural moisturizing factor (NMF), helping to maintain hydration and support the skin barrier. It is also used as a buffering agent and to improve the feel of formulations. |
| Glycine Amino acid / humectant | Glycine is a small amino acid used in skincare as a humectant and conditioning agent, supporting skin hydration and acting as a building block for collagen and natural moisturizing factor. It is generally considered well-tolerated and is often included as part of moisturizing or barrier-support formulations. |
| Sodium Chloride Thickener / viscosity adjuster | Sodium chloride (table salt) is commonly used in cosmetics as a thickening and viscosity-control agent, particularly in surfactant-based cleansers, and also acts as a mild abrasive in scrubs. It is generally well tolerated and considered a formulation ingredient rather than a treatment active. |
| Trehalose Humectant / moisturizer | Trehalose is a naturally occurring disaccharide used in skincare as a humectant and protective agent, helping retain moisture and stabilize cell membranes and proteins against dehydration and oxidative stress. It is well tolerated and commonly used to support skin barrier hydration. |
| Allantoin Key active Soothing/skin-conditioning agent | Allantoin is a naturally derived or synthetically produced compound used in skincare for its soothing, moisturizing, and keratolytic (skin-softening) properties. It promotes cell proliferation and helps calm irritation, commonly appearing in creams, lotions, and after-sun products. |
| Glutamic Acid Humectant / amino acid | Glutamic acid is a naturally occurring amino acid used in skincare as a humectant and component of the skin's natural moisturizing factor (NMF), helping to maintain hydration and support the skin barrier. It is also used as a pH adjuster and in some formulations to enhance moisturization. |
| Lysine Hci Amino acid / conditioning agent | Lysine HCl is the hydrochloride salt of the essential amino acid L-lysine, used in skincare primarily as a skin-conditioning and humectant agent that supports the skin's amino acid pool and may aid in maintaining hydration and barrier function. It is also a component involved in collagen synthesis, though topical evidence for structural benefits is limited. |
| Threonine Amino acid / skin conditioning agent | Threonine is an essential amino acid used in skincare primarily as a humectant and skin-conditioning agent, helping support hydration and the skin's natural moisturizing factor. It is also a building block for proteins such as collagen and elastin. |
| Arginine Amino acid / pH adjuster & conditioning agent | Arginine is a basic amino acid used in skincare primarily as a pH buffer/neutralizer and humectant-like conditioning agent that supports skin hydration and barrier function. It is generally well tolerated and often paired with acidic ingredients to balance formulation pH. |
| Glucose Humectant/skin-conditioning agent | Glucose is a simple sugar used in skincare primarily as a humectant and skin-conditioning ingredient, helping to attract and retain moisture in the skin. It can also serve as a substrate in formulations and contributes to the skin's natural moisturizing factors. |
| Proline Amino acid / skin-conditioning agent | Proline is a non-essential amino acid and a key component of collagen, used in skincare as a humectant and skin-conditioning agent to support hydration and the skin barrier. It is generally well tolerated and often included in formulations for its moisturizing and structural-protein-supporting properties. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.