Below is every ingredient in Nipfab Retinol Fix Overnight Cream 50Ml explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Bisabolol is a naturally derived (typically from chamomile) or synthetic terpene alcohol used in skincare for its anti-inflammatory, soothing, and skin-conditioning properties. It is also reported to enhance penetration of other ingredients and offers mild antimicrobial activity.
Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier.
Retinyl palmitate is an ester of retinol and palmitic acid used as a vitamin A source and antioxidant in skincare. It is converted in the skin to retinol and then retinoic acid, offering milder anti-aging and skin-conditioning effects than stronger retinoids.
Tocopherol (vitamin E) is a lipid-soluble antioxidant used in skincare to protect skin and formulations from oxidative damage caused by free radicals and UV exposure. It also functions as a skin-conditioning and emollient agent and can stabilize oils against rancidity.
Palmitoyl Tripeptide-1 is a synthetic palmitoylated peptide (sequence Gly-His-Lys) used in cosmetics to signal fibroblasts and support collagen and extracellular matrix synthesis. It is commonly combined with other peptides in anti-aging and firming formulations.
Palmitoyl Tetrapeptide-7 is a palmitoylated synthetic peptide used in cosmetic formulations, primarily marketed to help reduce inflammatory signaling and support a more even, firmer skin appearance. It is commonly paired with other peptides such as Palmitoyl Tripeptide-1 in anti-aging products.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
| Comedogenicity (pore-clogging) | Uncommon | May contribute to clogged pores or breakouts in acne-prone or oily skin, though shea is generally low on the comedogenic scale. |
| Allergic contact dermatitis | Rare | Sensitization is uncommon; despite tree-nut origin, refined shea butter contains negligible nut proteins and is rarely linked to nut allergy reactions. |
| Skin irritation or redness | Rare | Occasional mild irritation, often related to impurities in unrefined products or individual sensitivity. |
| Mild skin irritation | Rare | Generally well tolerated; occasional transient redness or stinging in sensitive individuals. |
| Comedogenicity / clogged pores | Uncommon | Low comedogenic potential, but may contribute to congestion in acne-prone skin at higher concentrations. |
| Contact urticaria | Very rare | Isolated case reports of immediate-type reactions. |
| Mild contact irritation | Rare | Occasional redness or stinging, usually in sensitive or compromised skin. |
| Mild skin irritation or redness | Rare | Generally considered non-irritating; occasional mild reactions reported. |
| Clogged pores / comedogenic-related breakouts | Uncommon | Often anecdotal; dimethicone is largely regarded as non-comedogenic but may trap debris if skin is not cleansed well. |
| Eye irritation on accidental contact | Rare | Transient stinging or discomfort if product enters the eyes. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Butyrospermum Parkii (Shea) Butter Emollient / occlusive moisturizer | Butyrospermum Parkii (Shea) Butter is a plant-derived fat extracted from the nuts of the African shea tree, rich in triglycerides and unsaponifiables. It is widely used in skincare to soften, smooth, and condition the skin while forming an occlusive barrier that reduces water loss. |
| Glyceryl Stearate Emulsifier/emollient | Glyceryl Stearate is a glycerol ester of stearic acid widely used as a non-ionic emulsifier and emollient to stabilize oil-in-water formulations and improve skin feel. It functions as a base/formulation ingredient rather than a therapeutic active. |
| Peg-100 Stearate Emulsifier/surfactant | PEG-100 Stearate is a polyethylene glycol ester of stearic acid used as a nonionic surfactant and emulsifier to stabilize oil-in-water formulations and improve skin feel. It functions as a formulation base ingredient rather than a therapeutic active. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Dimethicone Emollient/occlusive (silicone) | Dimethicone is a silicone-based polymer used in skincare to soften skin, smooth texture, and form a breathable protective barrier that reduces transepidermal water loss. It is widely used as a base/formulation ingredient rather than a therapeutic active. |
| Cetearyl Alcohol Emollient/emulsifier | Cetearyl alcohol is a fatty alcohol blend (cetyl and stearyl alcohol) used in skincare as an emollient, emulsion stabilizer, and thickening agent. It helps soften skin and keep oil and water phases blended in creams and lotions. |
| Benzyl Alcohol Preservative / solvent | Benzyl alcohol is an aromatic alcohol used primarily as a preservative and solvent in cosmetic formulations, and it also provides mild fragrance and viscosity-reducing properties. It is approved for use as a preservative at concentrations up to about 1% in leave-on and rinse-off products. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Polyacrylamide Thickener/film-former | Polyacrylamide is a synthetic polymer used in cosmetics primarily as a thickening agent, film former, and stabilizer that improves texture and viscosity of formulations. It is considered a base/formulation ingredient rather than a treatment active. |
| Bisabolol Key active Soothing/anti-inflammatory agent | Bisabolol is a naturally derived (typically from chamomile) or synthetic terpene alcohol used in skincare for its anti-inflammatory, soothing, and skin-conditioning properties. It is also reported to enhance penetration of other ingredients and offers mild antimicrobial activity. |
| Parfum (Fragrance) Fragrance/masking agent | Parfum (Fragrance) is a blend of aromatic compounds added to mask base odors and impart a pleasant scent to cosmetic products. It provides no skin-treatment benefit and is included for sensory and marketing purposes. |
| C13-14 Isoparaffin Emollient/thickener | C13-14 Isoparaffin is a synthetic hydrocarbon used in skincare primarily as an emollient and as a thickening or gelling agent, often paired with polyacrylamide-based systems to stabilize emulsions. It helps improve spreadability and texture but provides no active treatment benefit. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Sodium Stearoyl Glutamate Emulsifier / surfactant | Sodium Stearoyl Glutamate is a mild, amino-acid-derived (glutamic acid and stearic acid) anionic surfactant used primarily as an emulsifier and co-emulsifier to stabilize oil-in-water formulations. It is well tolerated and often chosen for gentle, naturally derived cosmetic systems. |
| Disodium Edta Chelating agent | Disodium EDTA is a chelating agent used in cosmetics to bind metal ions, improving product stability, preventing rancidity, and enhancing the efficacy of preservatives. It is a formulation/base ingredient rather than a treatment active. |
| Tocopheryl Acetate Key active Antioxidant | Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier. |
| Retinyl Palmitate Key active Antioxidant / retinoid (vitamin A derivative) | Retinyl palmitate is an ester of retinol and palmitic acid used as a vitamin A source and antioxidant in skincare. It is converted in the skin to retinol and then retinoic acid, offering milder anti-aging and skin-conditioning effects than stronger retinoids. |
| Dehydroacetic Acid Preservative | Dehydroacetic acid is a synthetic organic acid used primarily as a broad-spectrum antimicrobial preservative in cosmetic and skincare formulations, where it inhibits the growth of bacteria, yeast, and mold. It is often combined with other preservatives such as benzyl alcohol to enhance product stability and shelf life. |
| Laureth-7 Emulsifier/surfactant | Laureth-7 is a polyethylene glycol ether of lauryl alcohol used in cosmetics as a nonionic surfactant, emulsifier, and solubilizer to stabilize formulations and disperse oils. It functions as a formulation aid rather than a therapeutic active. |
| Benzyl Salicylate Fragrance/UV-absorber | Benzyl salicylate is an aromatic ester used primarily as a fragrance ingredient and, to a lesser extent, as a UV-light absorber in cosmetic formulations. It imparts a faint floral, balsamic scent and helps stabilize fragrance compositions. |
| Carbomer Thickener / gelling agent | Carbomer is a synthetic high-molecular-weight polymer of acrylic acid used to thicken, stabilize, and control the viscosity of gels, creams, and lotions. It functions as a formulation aid rather than a therapeutic active. |
| Sodium Lactate Humectant / NMF component | Sodium lactate is the sodium salt of lactic acid and a key component of skin's natural moisturizing factor (NMF), used to hydrate the skin and buffer formulation pH. It also has mild exfoliating and humectant properties that help maintain skin moisture and barrier function. |
| Hexyl Cinnamal Fragrance ingredient | Hexyl Cinnamal is a synthetic aromatic compound used as a fragrance and masking agent in cosmetic and skincare formulations, valued for its mild floral, jasmine-like scent. It is one of the 26 fragrance allergens required to be labeled in the EU. |
| Polysorbate 20 Emulsifier / solubilizer | Polysorbate 20 is a nonionic surfactant derived from sorbitol and lauric acid, used in skincare to solubilize fragrances and essential oils and to stabilize oil-in-water emulsions. It functions primarily as a formulation aid rather than a treatment active. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Linalool Fragrance/masking agent | Linalool is a naturally occurring terpene alcohol found in lavender, coriander, and many other plants, used in skincare primarily as a fragrance component. It readily oxidizes upon exposure to air, forming sensitizing hydroperoxides. |
| Limonene Fragrance/solvent | Limonene is a naturally occurring monoterpene derived from citrus peel oils, commonly used as a fragrance component and solvent in cosmetic formulations. On exposure to air it oxidizes, forming compounds with greater sensitizing potential. |
| Tocopherol Key active Antioxidant | Tocopherol (vitamin E) is a lipid-soluble antioxidant used in skincare to protect skin and formulations from oxidative damage caused by free radicals and UV exposure. It also functions as a skin-conditioning and emollient agent and can stabilize oils against rancidity. |
| Coumarin Fragrance ingredient | Coumarin is a naturally occurring aromatic compound used in cosmetics primarily as a fragrance and masking agent, valued for its sweet, hay-like scent. It is one of the 26 fragrance allergens that EU regulations require to be declared on product labels. |
| Palmitoyl Tripeptide-1 Key active Signal peptide / anti-aging active | Palmitoyl Tripeptide-1 is a synthetic palmitoylated peptide (sequence Gly-His-Lys) used in cosmetics to signal fibroblasts and support collagen and extracellular matrix synthesis. It is commonly combined with other peptides in anti-aging and firming formulations. |
| Palmitoyl Tetrapeptide-7 Key active Anti-aging signal peptide | Palmitoyl Tetrapeptide-7 is a palmitoylated synthetic peptide used in cosmetic formulations, primarily marketed to help reduce inflammatory signaling and support a more even, firmer skin appearance. It is commonly paired with other peptides such as Palmitoyl Tripeptide-1 in anti-aging products. |
| Citric Acid pH adjuster / AHA exfoliant | Citric acid is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formulation pH and as a chelating agent, and at higher concentrations as a mild chemical exfoliant. It can promote surface cell turnover and is sometimes included in antioxidant or brightening products. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.