Below is every ingredient in Re Equil 0 5 Retinol Night Cream Prevents Fine Lines Wrinkles 32 G explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Retinol is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover and stimulating collagen synthesis. It is widely used to address fine lines, photoaging, and acne.
Ascorbyl palmitate is a lipid-soluble, more stable ester of vitamin C (ascorbic acid) used as an antioxidant in skincare formulations. It can help protect formulas from oxidation and may offer some skin antioxidant benefits, though its conversion to active ascorbic acid in skin is limited.
Bidens Pilosa Extract is a plant-derived ingredient rich in polyphenols, flavonoids, and phytic compounds, used in skincare for antioxidant, anti-inflammatory, and retinol-like skin-conditioning effects. It is sometimes marketed as a gentler botanical alternative to retinoids for improving skin texture and tone.
Oxothiazolidine (Otz-10), or L-2-oxothiazolidine-4-carboxylic acid, is a cysteine prodrug that intracellularly converts to cysteine and boosts glutathione synthesis. In skincare it is used as an antioxidant and for potential brightening and protective effects against oxidative stress.
Physalis Angulata Extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and skin-conditioning properties, often included to help calm and protect the skin. It contains compounds such as physalins and flavonoids that may help mitigate oxidative stress.
4-Tert-Butylcyclohexanol is a synthetic ingredient used in skincare to reduce sensory irritation by inhibiting the TRPV1 receptor, helping calm sensitive or reactive skin. It is commonly added to formulations containing potentially irritating actives to improve tolerability.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild skin irritation | Rare | Generally considered non-irritating; isolated reactions possible in sensitive individuals. |
| Contact dermatitis / allergic reaction | Very rare | Allergy to this inert hydrocarbon is uncommon and poorly documented. |
| Acneiform breakouts (clogged pores) | Rare | Considered low comedogenicity, but heavy occlusive feel may contribute in acne-prone users. |
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
| Allergic contact dermatitis | Rare | Documented in patch-test studies but considered a relatively weak sensitizer. |
| Redness or itching | Rare | Typically resolves after discontinuation. |
| Skin irritation | Rare | Mild transient irritation occasionally reported in sensitive individuals. |
| Contact urticaria | Very rare | Rarely reported immediate hypersensitivity reaction. |
| Comedogenicity (pore-clogging) | Uncommon | As an occlusive lipid it may contribute to clogged pores or acne in acne-prone individuals, though it is generally considered low risk. |
| Contact irritation or mild redness | Rare | Occasional irritation reported, typically in sensitive skin or with impurities in lower-grade material. |
| Comedogenicity (pore clogging) | Rare | Low comedogenic potential but possible in acne-prone skin. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| C15-19 Alkane Emollient / skin-conditioning agent | C15-19 Alkane is a lightweight, plant-derived (often sugarcane-based) liquid hydrocarbon used as a silicone alternative emollient and solvent in cosmetic formulations. It provides slip, spreadability, and a smooth, non-greasy skin feel without adding active treatment benefits. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Ethylhexyl Methoxycrylene Photostabilizer / UV filter solubilizer | Ethylhexyl Methoxycrylene is a synthetic ingredient used in sunscreens to stabilize UV filters such as avobenzone and octinoxate, preventing their photodegradation upon sun exposure. It also acts as a solvent that helps dissolve other UV-absorbing compounds in the formulation. |
| Hydrogenated Rapeseed Oil Emollient / skin-conditioning agent | Hydrogenated Rapeseed Oil is a semi-solid lipid derived from rapeseed (canola) oil through hydrogenation, used in skincare as an emollient, texture enhancer, and skin-conditioning agent. It softens and smooths the skin while contributing to product consistency and stability. |
| Neopentyl Glycol Diheptanoate Emollient | Neopentyl Glycol Diheptanoate is a synthetic diester emollient used in skincare and cosmetics to provide a light, non-greasy skin feel and to soften and smooth the skin. It functions as a base/texture ingredient rather than a treatment active. |
| Octyldodecanol Emollient/solvent | Octyldodecanol is a branched fatty alcohol used in cosmetic formulations as an emollient, solvent, and skin-conditioning agent that improves spreadability and texture. It helps soften skin and dissolve other ingredients without functioning as a treatment active. |
| Macadamia Integrifolia Seed Oil Emollient / skin-conditioning oil | Macadamia Integrifolia Seed Oil is a plant-derived emollient rich in oleic and palmitoleic fatty acids, used to soften, condition, and provide occlusive moisturization to the skin. It functions as a base/carrier ingredient rather than a targeted treatment active. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Stearyl Alcohol Emollient/emulsifier | Stearyl alcohol is a fatty alcohol used in skincare as an emollient, emulsion stabilizer, and thickening agent to improve texture and prevent ingredient separation. It softens skin and helps maintain the consistency of creams and lotions. |
| Behenyl Alcohol Emollient / Thickener | Behenyl alcohol is a fatty alcohol derived from behenic acid that functions as an emollient, thickening agent, and emulsion stabilizer in cosmetic and skincare formulations. It helps soften the skin and improve product texture and stability. |
| Glyceryl Stearate Emulsifier/emollient | Glyceryl Stearate is a glycerol ester of stearic acid widely used as a non-ionic emulsifier and emollient to stabilize oil-in-water formulations and improve skin feel. It functions as a base/formulation ingredient rather than a therapeutic active. |
| Panthenol Humectant / skin-conditioning agent | Panthenol (provitamin B5) is converted to pantothenic acid in the skin, where it acts as a humectant and helps support skin barrier function and hydration. It is also used for its soothing and mild anti-inflammatory properties in topical formulations. |
| Pentaerythrityl Distearate Emollient / thickener | Pentaerythrityl Distearate is an ester of pentaerythritol and stearic acid used as an emollient, viscosity-modifier and texture enhancer in cosmetic formulations. It imparts a smooth, conditioning feel and helps stabilize emulsions. |
| Squalane Emollient / occlusive moisturizer | Squalane is a saturated, stable hydrocarbon derived from squalene (sourced from plants like olives or sugarcane, or shark liver) used as a lightweight emollient that softens skin and reinforces the skin barrier by reducing transepidermal water loss. It is well tolerated, non-comedogenic for most users, and serves as a base or carrier ingredient rather than a therapeutic active. |
| Propanediol Humectant/solvent | Propanediol is a plant-derived glycol used in skincare as a humectant, solvent, and penetration enhancer that improves moisturization and the spreadability of formulations. It also helps solubilize other ingredients and can boost the efficacy of certain actives. |
| Methyl Glucose Sesquistearate Emulsifier / emollient | Methyl Glucose Sesquistearate is a glucose-derived nonionic emulsifier used to stabilize oil-in-water emulsions and impart a smooth, conditioning skin feel. It is considered mild and is widely used as a formulation base ingredient rather than a treatment active. |
| Pentylene Glycol Humectant / solvent / preservative-booster | Pentylene glycol is a glycol used in cosmetics as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, helping reduce reliance on traditional preservatives. It improves skin hydration and aids the delivery and stability of other ingredients. |
| Retinol Key active Vitamin A derivative / anti-aging active | Retinol is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover and stimulating collagen synthesis. It is widely used to address fine lines, photoaging, and acne. |
| Glyceryl Dibehenate Emollient / emulsifier | Glyceryl Dibehenate is a glycerol ester of behenic acid used primarily as an emollient, emulsifier, and texture-enhancing agent in cosmetic formulations. It helps stabilize emulsions and impart a smooth, conditioned feel to the skin. |
| Hydroxyacetophenone Antioxidant / soothing agent | Hydroxyacetophenone (acetophenone-based compound, often 4'-hydroxyacetophenone) is used in skincare primarily as an antioxidant and skin-conditioning agent that can also enhance the stability and efficacy of preservative systems. It is valued for its soothing properties and helps neutralize free radicals while reducing potential irritation from other formulation components. |
| Sodium Polyacryloyldimethyl Taurate Emulsifier / thickener | Sodium Polyacryloyldimethyl Taurate is a synthetic acrylate-based polymer used as a thickening, stabilizing, and emulsifying agent in cosmetic formulations. It helps create smooth, gel-like textures and stabilizes oil-in-water emulsions. |
| Ascorbyl Palmitate Key active Antioxidant / Vitamin C derivative | Ascorbyl palmitate is a lipid-soluble, more stable ester of vitamin C (ascorbic acid) used as an antioxidant in skincare formulations. It can help protect formulas from oxidation and may offer some skin antioxidant benefits, though its conversion to active ascorbic acid in skin is limited. |
| Polysorbate 20 Emulsifier / solubilizer | Polysorbate 20 is a nonionic surfactant derived from sorbitol and lauric acid, used in skincare to solubilize fragrances and essential oils and to stabilize oil-in-water emulsions. It functions primarily as a formulation aid rather than a treatment active. |
| Glyceryl Caprylate Emollient / antimicrobial co-preservative | Glyceryl Caprylate is a monoglyceride derived from glycerin and caprylic acid, used in skincare as an emollient, moisturizing agent, and skin-conditioning component with mild antimicrobial properties that support preservation. It is commonly employed to help stabilize formulations and reduce reliance on conventional preservatives. |
| Sodium Stearoyl Glutamate Emulsifier / surfactant | Sodium Stearoyl Glutamate is a mild, amino-acid-derived (glutamic acid and stearic acid) anionic surfactant used primarily as an emulsifier and co-emulsifier to stabilize oil-in-water formulations. It is well tolerated and often chosen for gentle, naturally derived cosmetic systems. |
| Bidens Pilosa Extract Key active Botanical antioxidant/soothing extract | Bidens Pilosa Extract is a plant-derived ingredient rich in polyphenols, flavonoids, and phytic compounds, used in skincare for antioxidant, anti-inflammatory, and retinol-like skin-conditioning effects. It is sometimes marketed as a gentler botanical alternative to retinoids for improving skin texture and tone. |
| Oxothiazolidine (Otz-10) Key active Antioxidant / glutathione precursor | Oxothiazolidine (Otz-10), or L-2-oxothiazolidine-4-carboxylic acid, is a cysteine prodrug that intracellularly converts to cysteine and boosts glutathione synthesis. In skincare it is used as an antioxidant and for potential brightening and protective effects against oxidative stress. |
| Physalis Angulata Extract Key active Antioxidant/soothing botanical extract | Physalis Angulata Extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and skin-conditioning properties, often included to help calm and protect the skin. It contains compounds such as physalins and flavonoids that may help mitigate oxidative stress. |
| Peg-32 Stearate Emulsifier / surfactant | PEG-32 Stearate is a polyethylene glycol ester of stearic acid used as a nonionic emulsifier, surfactant, and emollient to stabilize oil-in-water formulations and improve texture. It is a formulation base ingredient rather than a therapeutic active. |
| Polyglyceryl-6 Distearate Emulsifier | Polyglyceryl-6 Distearate is a polyglycerol ester of stearic acid used as a non-ionic, oil-in-water emulsifier and emollient in cosmetic formulations. It helps stabilize emulsions and improve skin feel, and is generally considered well tolerated. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Arachidyl Alcohol Emollient / emulsion stabilizer | Arachidyl alcohol is a fatty alcohol (C20) derived from natural oils that functions as an emollient, thickener, and co-emulsifier to stabilize creams and lotions. It improves texture and helps maintain emulsion consistency in skincare formulations. |
| Bht Antioxidant/preservative | BHT (butylated hydroxytoluene) is a synthetic phenolic antioxidant used in small amounts to prevent oxidation and rancidity of oils, fragrances, and other unstable components, helping maintain product stability and shelf life. |
| Glyceryl Polyacrylate Hydrating film-former / thickener | Glyceryl Polyacrylate is a cross-linked polymer of acrylic acid and glycerin used in skincare to form a moisturizing film on the skin and to thicken or stabilize gel-based formulations. It functions primarily as a humectant and texture enhancer rather than as a treatment active. |
| 4-Tert-Butylcyclohexanol Key active Soothing agent / TRPV1 antagonist | 4-Tert-Butylcyclohexanol is a synthetic ingredient used in skincare to reduce sensory irritation by inhibiting the TRPV1 receptor, helping calm sensitive or reactive skin. It is commonly added to formulations containing potentially irritating actives to improve tolerability. |
| Caprylhydroxamic Acid Preservative / chelating agent | Caprylhydroxamic acid is a glycine-derived hydroxamic acid used primarily as a preservative and chelating agent in cosmetic formulations, where it helps control microbial growth (especially fungi) and stabilizes products by binding trace metal ions. It is typically used in combination with other preservatives such as glycols and is effective across a relatively wide pH range. |
| Bha Key active Chemical exfoliant | BHA (beta hydroxy acid), most commonly salicylic acid, is an oil-soluble exfoliant that penetrates pores to dissolve excess sebum and dead skin cells. It is widely used to treat acne, blackheads, and to improve skin texture and oiliness. |
| Polysorbate 60 Emulsifier / surfactant | Polysorbate 60 is a nonionic surfactant and emulsifier derived from sorbitol and stearic acid, used to blend oil and water phases and stabilize emulsions in creams and lotions. It functions as a formulation aid rather than a therapeutic active. |
| Sorbitan Isostearate Emulsifier / surfactant | Sorbitan isostearate is a sorbitan ester of isostearic acid used as a nonionic emulsifier and stabilizer in oil-in-water and water-in-oil cosmetic formulations. It helps blend oil and water phases and improves texture and spreadability. |
| Trisodium Ethylenediamine Disuccinate Chelating agent | Trisodium Ethylenediamine Disuccinate (Trisodium Ethylenediamine Disuccinate, or HEDTA-type biodegradable chelator) is a biodegradable chelating agent used to bind metal ions in cosmetic formulations. By sequestering trace metals, it helps stabilize products, prevent discoloration and rancidity, and enhance the efficacy of preservatives and antioxidants. |
| Lignoceryl Alcohol Emollient / co-emulsifier | Lignoceryl alcohol is a long-chain (C24) saturated fatty alcohol used in skincare as an emollient, thickener, and co-emulsifier to stabilize emulsions and improve skin feel. It softens and conditions the skin while contributing to product texture and viscosity. |
| Tocopherol Key active Antioxidant | Tocopherol (vitamin E) is a lipid-soluble antioxidant used in skincare to protect skin and formulations from oxidative damage caused by free radicals and UV exposure. It also functions as a skin-conditioning and emollient agent and can stabilize oils against rancidity. |
| Sodium Benzoate Preservative | Sodium benzoate is a salt of benzoic acid used as a preservative in cosmetic and skincare formulations to inhibit the growth of bacteria, yeast, and fungi, particularly in acidic products. It is most effective at a pH below 5. |
| Hydroxymethoxyphenyl Decanone Key active Soothing/anti-irritant | Hydroxymethoxyphenyl Decanone (sold as Sytenol A) is a synthetic compound used in skincare for its soothing and antioxidant properties, often paired with bakuchiol-type formulations. It helps calm irritation and supports the skin barrier. |
| Citric Acid pH adjuster / AHA exfoliant | Citric acid is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formulation pH and as a chelating agent, and at higher concentrations as a mild chemical exfoliant. It can promote surface cell turnover and is sometimes included in antioxidant or brightening products. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.