Below is every ingredient in Rodial Retinol Overnight Gel 50 Ml explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Ascorbyl Tetraisopalmitate is a lipid-soluble, stabilized derivative of vitamin C used in skincare for antioxidant protection and brightening. It penetrates the skin's lipid layers and is converted to ascorbic acid, supporting collagen synthesis and reducing hyperpigmentation.
Tocopherol (vitamin E) is a lipid-soluble antioxidant used in skincare to protect skin and formulations from oxidative damage caused by free radicals and UV exposure. It also functions as a skin-conditioning and emollient agent and can stabilize oils against rancidity.
Retinol is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover and stimulating collagen synthesis. It is widely used to address fine lines, photoaging, and acne.
Decapeptide-22 is a synthetic ten-amino-acid signal peptide used in cosmetic formulations, primarily explored for its potential to modulate melanogenesis and support skin brightening. It is typically incorporated into topical products at low concentrations as a targeted active.
Oligopeptide-78 is a synthetic signaling peptide used in cosmetic formulations for its proposed skin-conditioning and barrier-supporting effects. It is typically incorporated into serums and creams marketed for soothing or anti-aging benefits.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild skin irritation or redness | Rare | Generally considered non-irritating; occasional mild reactions reported. |
| Clogged pores / comedogenic-related breakouts | Uncommon | Often anecdotal; dimethicone is largely regarded as non-comedogenic but may trap debris if skin is not cleansed well. |
| Allergic contact dermatitis | Very rare | True silicone allergy is exceptionally uncommon. |
| Eye irritation on accidental contact | Rare | Transient stinging or discomfort if product enters the eyes. |
| Mild skin irritation | Rare | Generally considered non-irritating; occasional mild reactions reported. |
| Contact allergy/sensitization | Very rare | Silicones are low-allergenicity; documented allergic reactions are exceptional. |
| Eye irritation | Rare | Possible transient stinging if product enters the eyes. |
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
| Mild skin irritation or stinging | Common | More likely at higher concentrations or on compromised/sensitive skin |
| Irritant contact dermatitis | Uncommon | Non-allergic irritation, often dose-dependent |
| Worsening of pre-existing eczema or barrier-impaired skin | Rare | Penetration-enhancing effect may increase reactivity |
| Systemic toxicity from topical use | Very rare | Reported mainly with extensive application on broken skin, especially in infants or burn patients |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Dimethicone Emollient/occlusive (silicone) | Dimethicone is a silicone-based polymer used in skincare to soften skin, smooth texture, and form a breathable protective barrier that reduces transepidermal water loss. It is widely used as a base/formulation ingredient rather than a therapeutic active. |
| Cyclopentasiloxane Emollient/silicone | Cyclopentasiloxane is a volatile cyclic silicone widely used in skincare and cosmetics to impart a smooth, silky feel and spreadability before evaporating, leaving no greasy residue. It also serves as a carrier and helps reduce tackiness in formulations. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Propylene Glycol Humectant / solvent | Propylene glycol is a small glycol molecule widely used in skincare as a humectant, solvent, and penetration enhancer that helps attract water and dissolve other ingredients. It is considered a base/formulation ingredient rather than a therapeutic active. |
| Polysilicone-11 Film-former / texturizer | Polysilicone-11 is a silicone-based crosslinked polymer used in cosmetics to form a smooth, flexible film on the skin, providing mattifying, blurring, and texture-improving effects. It is commonly found in primers, foundations, and sunscreens as a formulation ingredient rather than a treatment active. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Polyacrylamide Thickener/film-former | Polyacrylamide is a synthetic polymer used in cosmetics primarily as a thickening agent, film former, and stabilizer that improves texture and viscosity of formulations. It is considered a base/formulation ingredient rather than a treatment active. |
| Sodium Polyacrylate Thickener / absorbent | Sodium polyacrylate is a superabsorbent acrylic-acid polymer used in skincare as a thickening, stabilizing, and water-binding agent that can hold large amounts of liquid to create gel-like textures. It functions as a formulation and texture-enhancing ingredient rather than a biologically active treatment. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| C13-14 Isoparaffin Emollient/thickener | C13-14 Isoparaffin is a synthetic hydrocarbon used in skincare primarily as an emollient and as a thickening or gelling agent, often paired with polyacrylamide-based systems to stabilize emulsions. It helps improve spreadability and texture but provides no active treatment benefit. |
| Polysorbate 20 Emulsifier / solubilizer | Polysorbate 20 is a nonionic surfactant derived from sorbitol and lauric acid, used in skincare to solubilize fragrances and essential oils and to stabilize oil-in-water emulsions. It functions primarily as a formulation aid rather than a treatment active. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Trideceth-6 Surfactant/emulsifier | Trideceth-6 is a polyethylene glycol ether of tridecyl alcohol used as a nonionic surfactant, emulsifier, and solubilizer in cosmetic formulations. It helps blend oil and water phases and disperse fragrances or other oily components in water-based products. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Ascorbyl Tetraisopalmitate Key active Antioxidant / Vitamin C derivative | Ascorbyl Tetraisopalmitate is a lipid-soluble, stabilized derivative of vitamin C used in skincare for antioxidant protection and brightening. It penetrates the skin's lipid layers and is converted to ascorbic acid, supporting collagen synthesis and reducing hyperpigmentation. |
| Disodium Edta Chelating agent | Disodium EDTA is a chelating agent used in cosmetics to bind metal ions, improving product stability, preventing rancidity, and enhancing the efficacy of preservatives. It is a formulation/base ingredient rather than a treatment active. |
| Laureth-7 Emulsifier/surfactant | Laureth-7 is a polyethylene glycol ether of lauryl alcohol used in cosmetics as a nonionic surfactant, emulsifier, and solubilizer to stabilize formulations and disperse oils. It functions as a formulation aid rather than a therapeutic active. |
| Tocopherol Key active Antioxidant | Tocopherol (vitamin E) is a lipid-soluble antioxidant used in skincare to protect skin and formulations from oxidative damage caused by free radicals and UV exposure. It also functions as a skin-conditioning and emollient agent and can stabilize oils against rancidity. |
| Polymethylsilsesquioxane Texture enhancer / mattifying agent | Polymethylsilsesquioxane is a silicone-based spherical powder used in skincare and cosmetics to impart a smooth, soft-focus, mattifying feel and improve spreadability. It is a formulation/texture ingredient rather than a treatment active. |
| Parfum (Fragrance) Fragrance/masking agent | Parfum (Fragrance) is a blend of aromatic compounds added to mask base odors and impart a pleasant scent to cosmetic products. It provides no skin-treatment benefit and is included for sensory and marketing purposes. |
| Hydrolyzed Wheat Protein Conditioning agent / humectant | Hydrolyzed wheat protein is a wheat-derived protein broken into smaller peptides and amino acids, used in skincare and haircare to improve hydration, film-forming, and conditioning by binding water and temporarily smoothing the skin or hair surface. It is generally well tolerated as a cosmetic functional ingredient. |
| Sodium Hydroxide pH adjuster | Sodium hydroxide (lye) is a strong alkaline compound used in small amounts to adjust and stabilize the pH of cosmetic formulations. At regulated low concentrations in finished products it is considered safe, though it is corrosive in concentrated form. |
| Lecithin Emollient / Emulsifier | Lecithin is a naturally occurring phospholipid (commonly derived from soybean or egg) used in skincare as an emulsifier, emollient, and penetration enhancer. It helps stabilize oil-and-water formulations and supports the skin barrier by mimicking natural lipids. |
| Peg/Ppg-18/18 Dimethicone Silicone-based emulsifier/conditioning agent | PEG/PPG-18/18 Dimethicone is a water-dispersible silicone surfactant used to emulsify, stabilize, and impart a smooth, silky feel to skincare and cosmetic formulations. It functions primarily as an emulsifier and skin-conditioning agent rather than a therapeutic active. |
| Retinol Key active Vitamin A derivative / anti-aging active | Retinol is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover and stimulating collagen synthesis. It is widely used to address fine lines, photoaging, and acne. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Ethylhexyl Cocoate Emollient/skin-conditioning ester | Ethylhexyl Cocoate is a lightweight ester derived from coconut-derived fatty acids and 2-ethylhexanol, used as an emollient and spreading agent that gives a smooth, non-greasy skin feel. It functions primarily as a texture-enhancing and conditioning ingredient in lotions, sunscreens, and color cosmetics. |
| Dimethiconol Emollient/silicone conditioning agent | Dimethiconol is a silicone-based polymer used in skincare and haircare to provide smoothing, conditioning, and a soft, non-greasy emollient feel. It forms a thin, breathable film that reduces moisture loss and improves spreadability of formulations. |
| Citronellol Fragrance ingredient | Citronellol is a naturally occurring monoterpene alcohol used as a fragrance and flavoring agent, providing a rose-like, citrusy scent in cosmetics and personal care products. It is found in essential oils such as rose, geranium, and citronella. |
| Decapeptide-22 Key active Skin-conditioning peptide / signal peptide | Decapeptide-22 is a synthetic ten-amino-acid signal peptide used in cosmetic formulations, primarily explored for its potential to modulate melanogenesis and support skin brightening. It is typically incorporated into topical products at low concentrations as a targeted active. |
| Oligopeptide-78 Key active Signal peptide / skin-conditioning agent | Oligopeptide-78 is a synthetic signaling peptide used in cosmetic formulations for its proposed skin-conditioning and barrier-supporting effects. It is typically incorporated into serums and creams marketed for soothing or anti-aging benefits. |
| Palmitoyl Decapeptide-21 Key active Signal peptide / skin-conditioning agent | Palmitoyl Decapeptide-21 is a lipidated synthetic signal peptide used in anti-aging formulations, intended to support extracellular matrix proteins and improve the appearance of skin firmness and texture. The palmitoyl group enhances skin penetration of the peptide sequence. |
| Zinc Palmitoyl Nonapeptide-14 Key active Sebum-regulating peptide | Zinc Palmitoyl Nonapeptide-14 is a lipidated copper/zinc-bound peptide combination used in cosmetic formulations primarily to help regulate sebum production and reduce the appearance of enlarged pores and oily skin. It is marketed for blemish-prone and oily skin types, often paired with other actives targeting excess oiliness. |
| Alpha-Isomethyl Ionone Fragrance ingredient | Alpha-Isomethyl Ionone is a synthetic fragrance compound with a sweet, violet-like floral scent used to impart or enhance aroma in cosmetic and skincare formulations. It has no therapeutic skin benefit and serves purely an olfactory/sensory role. |
| Limonene Fragrance/solvent | Limonene is a naturally occurring monoterpene derived from citrus peel oils, commonly used as a fragrance component and solvent in cosmetic formulations. On exposure to air it oxidizes, forming compounds with greater sensitizing potential. |
| Dimethylmethoxy Chromanyl Palmitate Key active Antioxidant | Dimethylmethoxy Chromanyl Palmitate is a synthetic, lipid-soluble antioxidant (a chromane derivative, often referred to by the trade name Lipochroman) used in skincare to neutralize free radicals and protect cells from oxidative and nitrosative stress. It is valued for its broad-spectrum reactive oxygen and nitrogen species scavenging activity and stability in formulations. |
| Bht Antioxidant/preservative | BHT (butylated hydroxytoluene) is a synthetic phenolic antioxidant used in small amounts to prevent oxidation and rancidity of oils, fragrances, and other unstable components, helping maintain product stability and shelf life. |
| Diamond Powder Exfoliant / luxury abrasive | Diamond powder is a finely milled inert mineral used in skincare primarily as a physical exfoliant and light-reflecting agent to give skin a smoother appearance and subtle radiance. It has no biochemical activity and functions mechanically rather than as a treatment active. |
| Silver Vine Extract Key active Antioxidant / soothing botanical | Silver Vine (Actinidia polygama) extract is a plant-derived ingredient used in skincare for its antioxidant and anti-inflammatory polyphenols, often included to help soothe and protect skin against oxidative stress. It is typically used as a supportive botanical rather than a primary clinical active. |
| Bha Key active Chemical exfoliant | BHA (beta hydroxy acid), most commonly salicylic acid, is an oil-soluble exfoliant that penetrates pores to dissolve excess sebum and dead skin cells. It is widely used to treat acne, blackheads, and to improve skin texture and oiliness. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.