Below is every ingredient in Skin1004 Madagascar Centella Hyalu Cica Sleeping Night Cream explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Hyaluronic acid is a glycosaminoglycan that attracts and binds water to the skin, helping to maintain hydration and improve the appearance of plumpness and smoothness. It is widely used in moisturizers and serums and is generally well tolerated across skin types.
Adenosine is a nucleoside that signals through cell-surface receptors to promote dermal fibroblast activity and collagen/elastin production, helping reduce the appearance of fine lines and wrinkles. It also has anti-inflammatory and soothing properties at low concentrations commonly used in cosmetics (around 0.04-0.1%).
Hedera helix (ivy) leaf/stem extract is a plant-derived ingredient used in cosmetics for its purported anti-inflammatory, antioxidant, and tonifying properties, often included in products marketed for reducing puffiness or improving skin tone. It contains saponins (hederacosides) and flavonoids that are believed to support microcirculation and skin conditioning.
Artemisia Princeps Leaf Extract is derived from Japanese mugwort and is used in skincare for its antioxidant, anti-inflammatory, and skin-soothing properties, attributed to compounds like flavonoids and eupatilin. It is commonly included in formulations targeting sensitive, irritated, or compromised skin.
Hydrolyzed Gardenia Florida Extract is a botanical-derived ingredient obtained by hydrolyzing extracts of the gardenia plant, used in skincare for its antioxidant and skin-conditioning properties. It is valued for components such as iridoid glycosides and crocetin derivatives that may help support skin barrier and provide soothing effects.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Skin dryness or barrier disruption with excessive contact | Uncommon | Frequent or prolonged exposure to water, especially hot or hard water, can disrupt the skin barrier and contribute to transepidermal water loss. |
| Irritation from impurities or hard water minerals | Rare | Reactions are attributed to contaminants, chlorine, or mineral content rather than water itself. |
| Mild transient stinging or irritation | Uncommon | More likely on broken or compromised skin or at high concentrations. |
| Allergic contact dermatitis | Rare | Documented in patch-test studies but considered a relatively weak sensitizer. |
| Redness or itching | Rare | Typically resolves after discontinuation. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
| Mild transient skin irritation or stinging | Uncommon | More likely at higher concentrations or on compromised skin barriers. |
| Contact dermatitis / allergic sensitization | Rare | Occasional case reports; patch testing can confirm. |
| Eye irritation on accidental contact | Uncommon | Relevant mainly in leave-on or rinse-off products near the eye area. |
| Mild transient flushing or redness | Uncommon | More likely at higher concentrations or in sensitive skin; usually subsides quickly. |
| Tingling, stinging, or burning sensation | Uncommon | Often associated with higher percentages or compromised barrier. |
| Contact irritation or itching | Rare | Generally dose-dependent and resolves with discontinuation. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Water Solvent/vehicle | Water is the most common base ingredient in cosmetic formulations, serving as a solvent that dissolves other ingredients and forms the bulk of emulsions and aqueous solutions. It is generally considered safe and non-irritating. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| 2-Hexanediol Humectant/preservative-booster | 1,2-Hexanediol (commonly written 2-hexanediol) is a multifunctional diol used in skincare primarily as a humectant, solvent, and preservative-enhancing agent that improves the antimicrobial efficacy of formulations. It is generally well tolerated and considered a base/formulation ingredient rather than a treatment active. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Polyglutamic Acid Humectant | Polyglutamic acid is a biodegradable peptide-based humectant that binds water to the skin's surface, helping to increase hydration and improve skin smoothness. It is often used alongside or as an alternative to hyaluronic acid. |
| Pantolactone Humectant / conditioning agent | Pantolactone is a lactone derivative of pantothenic acid (provitamin B5) used in skincare as a moisturizing and skin-conditioning ingredient. It can serve as a precursor to panthenol and helps support skin hydration and barrier function. |
| Hibiscus Esculentus Fruit Extract Skin-conditioning / humectant | Hibiscus Esculentus (okra) Fruit Extract is a plant-derived ingredient rich in mucilage polysaccharides, vitamins, and flavonoids, used in skincare for its hydrating, soothing, and film-forming conditioning properties. It is generally considered a mild, supportive cosmetic ingredient rather than a clinically established treatment active. |
| Carbomer Thickener / gelling agent | Carbomer is a synthetic high-molecular-weight polymer of acrylic acid used to thicken, stabilize, and control the viscosity of gels, creams, and lotions. It functions as a formulation aid rather than a therapeutic active. |
| Panthenol Humectant / skin-conditioning agent | Panthenol (provitamin B5) is converted to pantothenic acid in the skin, where it acts as a humectant and helps support skin barrier function and hydration. It is also used for its soothing and mild anti-inflammatory properties in topical formulations. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Hydrolyzed Hyaluronic Acid Humectant / moisturizer | Hydrolyzed hyaluronic acid is a low-molecular-weight form of hyaluronic acid broken into smaller fragments, allowing better penetration into the skin to bind water and improve hydration. It is widely used in moisturizers and serums to enhance skin moisture content and surface smoothness. |
| Hyaluronic Acid Key active Humectant / hydrating agent | Hyaluronic acid is a glycosaminoglycan that attracts and binds water to the skin, helping to maintain hydration and improve the appearance of plumpness and smoothness. It is widely used in moisturizers and serums and is generally well tolerated across skin types. |
| Cetearyl Olivate Emulsifier / emollient | Cetearyl Olivate is an olive oil-derived emulsifier and emollient, typically used with Sorbitan Olivate, that helps blend oil and water phases while conditioning and softening the skin. It supports the skin barrier and gives formulations a light, non-greasy feel. |
| Methylpropanediol Humectant/solvent | Methylpropanediol is a small glycol-type ingredient used in skincare as a humectant and solvent that helps hydrate skin and enhance the penetration of other actives. It also contributes to product texture and can support preservative efficacy. |
| Arginine Amino acid / pH adjuster & conditioning agent | Arginine is a basic amino acid used in skincare primarily as a pH buffer/neutralizer and humectant-like conditioning agent that supports skin hydration and barrier function. It is generally well tolerated and often paired with acidic ingredients to balance formulation pH. |
| Pullulan Film-forming agent / texturizer | Pullulan is a naturally derived polysaccharide produced by fermentation of starch by the fungus Aureobasidium pullulans. In skincare it forms a thin, breathable film on the skin, providing a temporary tightening or smoothing effect and helping to stabilize formulations. |
| Sorbitan Olivate Emulsifier | Sorbitan Olivate is an olive-derived ester of sorbitol and olive oil fatty acids used as a non-ionic emulsifier and emollient. It is often paired with Cetearyl Olivate (as Olivem 1000) to stabilize oil-in-water emulsions and impart a soft skin feel. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Pyrus Communis (Pear) Fruit Extract Skin-conditioning/humectant | Pyrus Communis (Pear) Fruit Extract is derived from pear fruit and is used in cosmetics as a skin-conditioning agent, offering humectant, mild antioxidant, and soothing properties due to its content of sugars, vitamins, and organic acids. It is typically included to support hydration and improve skin feel rather than as a primary clinical active. |
| Adenosine Key active Anti-aging/soothing active | Adenosine is a nucleoside that signals through cell-surface receptors to promote dermal fibroblast activity and collagen/elastin production, helping reduce the appearance of fine lines and wrinkles. It also has anti-inflammatory and soothing properties at low concentrations commonly used in cosmetics (around 0.04-0.1%). |
| Rosa Damascena Flower Water Soothing/aromatic floral water (hydrosol) | Rosa Damascena Flower Water is a water-based distillate of damask rose petals used in skincare as a mild humectant, toner, and fragrance component. It provides light soothing and astringent properties but contributes minimal active treatment benefit. |
| Cucumis Melo (Melon) Fruit Extract Emollient/Antioxidant | Cucumis Melo (Melon) Fruit Extract is derived from melon fruit and used in skincare for its hydrating, soothing, and antioxidant properties, owing to vitamins, amino acids, and natural sugars. It is generally used as a conditioning and skin-protective additive rather than a clinically validated active. |
| Iris Florentina Root Extract Skin conditioning / fragrance | Iris Florentina (orris) root extract is derived from the rhizome of the iris plant and is used in skincare primarily as a fragrance component and skin-conditioning agent, valued for its aromatic and emollient properties. It is sometimes claimed to have antioxidant and astringent effects, though clinical evidence is limited. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Hedera Helix (Ivy) Leaf/Stem Extract Key active Anti-inflammatory / botanical extract | Hedera helix (ivy) leaf/stem extract is a plant-derived ingredient used in cosmetics for its purported anti-inflammatory, antioxidant, and tonifying properties, often included in products marketed for reducing puffiness or improving skin tone. It contains saponins (hederacosides) and flavonoids that are believed to support microcirculation and skin conditioning. |
| Sodium Phytate Chelating agent | Sodium Phytate is the sodium salt of phytic acid used in cosmetic formulations primarily as a chelating agent to bind metal ions, improving product stability and preventing oxidation. It can also offer mild antioxidant support and is often included at low concentrations. |
| Xanthan Gum Thickener/stabilizer | Xanthan gum is a polysaccharide produced by bacterial fermentation, used in skincare as a thickening, gelling, and emulsion-stabilizing agent. It improves product texture and suspension of ingredients without contributing active treatment effects. |
| Maltodextrin Carrier/film-forming agent | Maltodextrin is a polysaccharide derived from starch hydrolysis, used in skincare primarily as a carrier, bulking agent, film former, and stabilizer for active ingredients and powders. It also helps improve texture and can act as a mild thickening or emulsion-stabilizing aid. |
| Artemisia Princeps Leaf Extract Key active Soothing/antioxidant botanical extract | Artemisia Princeps Leaf Extract is derived from Japanese mugwort and is used in skincare for its antioxidant, anti-inflammatory, and skin-soothing properties, attributed to compounds like flavonoids and eupatilin. It is commonly included in formulations targeting sensitive, irritated, or compromised skin. |
| Hydrolyzed Gardenia Florida Extract Key active Antioxidant/skin-conditioning | Hydrolyzed Gardenia Florida Extract is a botanical-derived ingredient obtained by hydrolyzing extracts of the gardenia plant, used in skincare for its antioxidant and skin-conditioning properties. It is valued for components such as iridoid glycosides and crocetin derivatives that may help support skin barrier and provide soothing effects. |
| Melatonin Key active Antioxidant | Melatonin is a hormone and potent antioxidant used topically to neutralize free radicals and support the skin's natural repair processes, particularly against UV-induced oxidative stress. It is often combined with other antioxidants like vitamins C and E for enhanced protection. |
| Illicium Verum (Anise) Fruit Extract Fragrance/antimicrobial extract | Illicium Verum (Anise) Fruit Extract is a plant-derived extract used in cosmetics primarily for its aromatic, antioxidant, and mild antimicrobial properties. It contains anethole and other volatile compounds that contribute fragrance and some preservative-boosting effects. |
| Larix Sibirica Wood Extract Key active Antioxidant / skin conditioning | Larix Sibirica Wood Extract is derived from Siberian larch wood and is a source of the flavonoid dihydroquercetin (taxifolin) and arabinogalactan. It is used in skincare for antioxidant and skin-conditioning effects, helping to protect against oxidative stress. |
| Quercus Mongolica Leaf Extract Key active Antioxidant/soothing botanical extract | Quercus Mongolica Leaf Extract is derived from the leaves of the Mongolian oak and is used in skincare primarily for its antioxidant and anti-inflammatory properties, attributed to polyphenols and tannins. It is typically included as a supportive botanical rather than a primary clinical active. |
| Persicaria Hydropiper Extract Key active Antioxidant/soothing botanical extract | Persicaria Hydropiper (water pepper) Extract is a plant-derived ingredient used in skincare for its antioxidant, anti-inflammatory, and skin-conditioning properties, attributed to flavonoids and polyphenols. It is typically incorporated to help soothe and protect skin against oxidative stress. |
| Rheum Palmatum Root/Stalk Extract Key active Antioxidant/Soothing botanical | Rheum Palmatum (Chinese rhubarb) root/stalk extract is a plant-derived ingredient containing anthraquinones, stilbenes (such as rhaponticin) and polyphenols valued in skincare for antioxidant, anti-inflammatory and skin-conditioning properties. It is used in formulations targeting irritation, oxidative stress and uneven tone. |
| Asarum Sieboldii Root Extract Key active Botanical extract (anti-inflammatory/antimicrobial) | Asarum Sieboldii Root Extract is derived from the wild ginger plant and is used in skincare for its purported anti-inflammatory, antimicrobial, and antioxidant properties. It contains volatile compounds including asarones and essential oils that may also contribute to fragrance. |
| Chrysanthellum Indicum Extract Key active Antioxidant / anti-inflammatory botanical | Chrysanthellum Indicum Extract is a plant-derived extract rich in flavonoids and saponins, used in skincare for its antioxidant, anti-inflammatory, and microcirculation-supporting properties. It is often included in formulations targeting redness, rosacea, and capillary fragility. |
| Corydalis Turtschaninovii Root Extract Key active Antioxidant / soothing botanical extract | Corydalis Turtschaninovii Root Extract is a plant-derived ingredient used in skincare for its reported antioxidant and anti-inflammatory properties, often included to help soothe and protect the skin. It contains alkaloids and other phytochemicals studied for potential calming effects on irritated skin. |
| Coptis Japonica Root Extract Key active Antioxidant/soothing botanical extract | Coptis Japonica Root Extract is a plant-derived ingredient rich in alkaloids such as berberine, valued in skincare for its antioxidant, anti-inflammatory, and antimicrobial properties. It is commonly included to help calm irritation and may support brightening and protection against oxidative stress. |
| Machilus Thunbergii Bark Extract Key active Antioxidant / soothing botanical extract | Machilus Thunbergii bark extract is a plant-derived ingredient valued for its antioxidant and anti-inflammatory properties, often included in skincare to help protect against oxidative stress and soothe the skin. It contains lignans and other polyphenolic compounds thought to contribute to its skin-conditioning effects. |
| Pentylene Glycol Humectant / solvent / preservative-booster | Pentylene glycol is a glycol used in cosmetics as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, helping reduce reliance on traditional preservatives. It improves skin hydration and aids the delivery and stability of other ingredients. |
| Hydrogenated Lecithin Emollient / Emulsifier | Hydrogenated lecithin is a phospholipid derived from lecithin through hydrogenation, used in skincare as an emulsifier, emollient, and skin-conditioning agent. It also helps stabilize formulations and form liposomes that can aid delivery of other ingredients. |
| Ceramide Np Skin-barrier replenishing lipid / emollient | Ceramide NP (formerly ceramide 3) is a naturally occurring sphingolipid that helps restore and maintain the skin's lipid barrier, reducing transepidermal water loss and improving hydration. It is widely used in moisturizers and barrier-repair formulations. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.