Below is every ingredient in The Derma Co 10 Niacinamide Serum 30Ml explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Zinc PCA is the zinc salt of pyrrolidone carboxylic acid used in skincare to help control excess sebum, support antimicrobial activity, and provide mild hydration. It is commonly included in products targeting oily and acne-prone skin.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient flushing or redness | Uncommon | More likely at higher concentrations or in sensitive skin; usually subsides quickly. |
| Tingling, stinging, or burning sensation | Uncommon | Often associated with higher percentages or compromised barrier. |
| Contact irritation or itching | Rare | Generally dose-dependent and resolves with discontinuation. |
| Allergic contact dermatitis | Very rare | Documented in isolated case reports; true sensitization is unusual. |
| Mild skin irritation or stinging | Common | More likely at higher concentrations or on compromised/sensitive skin |
| Irritant contact dermatitis | Uncommon | Non-allergic irritation, often dose-dependent |
| Worsening of pre-existing eczema or barrier-impaired skin | Rare | Penetration-enhancing effect may increase reactivity |
| Systemic toxicity from topical use | Very rare | Reported mainly with extensive application on broken skin, especially in infants or burn patients |
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
| Redness (erythema) | Uncommon | Typically mild and temporary at application site. |
| Dryness or skin tightness | Rare | May occur with overuse due to sebum-reducing effect. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Propylene Glycol Humectant / solvent | Propylene glycol is a small glycol molecule widely used in skincare as a humectant, solvent, and penetration enhancer that helps attract water and dissolve other ingredients. It is considered a base/formulation ingredient rather than a therapeutic active. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Zinc Pca Key active Sebum-regulating, antimicrobial | Zinc PCA is the zinc salt of pyrrolidone carboxylic acid used in skincare to help control excess sebum, support antimicrobial activity, and provide mild hydration. It is commonly included in products targeting oily and acne-prone skin. |
| Diethylene Glycol Monoethyl Ether Solvent / penetration enhancer | Diethylene glycol monoethyl ether (ethoxydiglycol) is a versatile solvent and penetration enhancer used in cosmetic and topical formulations to dissolve active ingredients and improve their absorption into the skin. It also functions as a viscosity reducer and coupling agent in mixed-phase products. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Hydroxyethyl Cellulose Thickener / viscosity modifier | Hydroxyethyl cellulose is a non-ionic, water-soluble cellulose derivative used to thicken and stabilize aqueous skincare formulations and improve texture. It functions as a rheology modifier and film-forming agent rather than a biologically active treatment ingredient. |
| Xanthan Gum Thickener/stabilizer | Xanthan gum is a polysaccharide produced by bacterial fermentation, used in skincare as a thickening, gelling, and emulsion-stabilizing agent. It improves product texture and suspension of ingredients without contributing active treatment effects. |
| Citric Acid pH adjuster / AHA exfoliant | Citric acid is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formulation pH and as a chelating agent, and at higher concentrations as a mild chemical exfoliant. It can promote surface cell turnover and is sometimes included in antioxidant or brightening products. |
| Perfume Fragrance | Perfume (fragrance) is a blend of aromatic compounds added to cosmetic products to impart a desired scent or to mask the base odor of other ingredients. It serves a sensory and formulation role rather than a skin-treating function. |
| Diazolidinyl Urea Preservative (antimicrobial) | Diazolidinyl urea is a formaldehyde-releasing preservative used to prevent microbial growth in cosmetics and personal care products. It is effective against bacteria and some fungi and is commonly found in creams, lotions, and shampoos. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Sodium Gluconate Chelating agent / skin-conditioning | Sodium gluconate is the sodium salt of gluconic acid used in skincare primarily as a chelating agent to bind metal ions and stabilize formulations, with secondary humectant and skin-conditioning properties. It is generally considered a base/formulation ingredient rather than an active treatment. |
| Iodopropynyl Butylcarbamate Preservative | Iodopropynyl Butylcarbamate (IPBC) is a broad-spectrum antimicrobial preservative used in cosmetics and personal care products primarily to protect against fungal and bacterial contamination. It is typically used at very low concentrations within regulatory limits. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.