Below is every ingredient in The Derma Co Skin Renew Peptide Retinol Serum Cream With Peptide Retinol 30 Ml 759 explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Alpha arbutin is a naturally derived hydroquinone derivative that inhibits tyrosinase, reducing melanin production. It is used to address hyperpigmentation, dark spots, and uneven skin tone.
Retinol is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover and stimulating collagen synthesis. It is widely used to address fine lines, photoaging, and acne.
Palmitoyl Tripeptide-1 is a synthetic palmitoylated peptide (sequence Gly-His-Lys) used in cosmetics to signal fibroblasts and support collagen and extracellular matrix synthesis. It is commonly combined with other peptides in anti-aging and firming formulations.
Palmitoyl Tetrapeptide-7 is a palmitoylated synthetic peptide used in cosmetic formulations, primarily marketed to help reduce inflammatory signaling and support a more even, firmer skin appearance. It is commonly paired with other peptides such as Palmitoyl Tripeptide-1 in anti-aging products.
Ascorbyl Glucoside is a stable, water-soluble vitamin C derivative that is enzymatically converted to ascorbic acid in the skin, providing antioxidant protection and supporting collagen synthesis and skin brightening. It is generally considered milder and more stable than pure L-ascorbic acid.
Retinaldehyde (retinal) is a vitamin A derivative that is converted to retinoic acid in the skin, used to promote cell turnover, improve photoaging, and reduce acne. It is considered more potent than retinol but generally better tolerated than prescription retinoic acid.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Skin irritation | Rare | Generally well tolerated; mild irritation possible in sensitive individuals. |
| Contact dermatitis / allergic reaction | Very rare | Allergic sensitization is uncommon for this inert hydrocarbon. |
| Comedogenicity / clogged pores | Very rare | Considered low comedogenic, but heavy occlusive use may contribute in acne-prone skin. |
| Allergic contact dermatitis | Very rare | Sensitization is uncommon; isolated reports only. |
| Eye irritation | Rare | Possible transient stinging if product enters the eyes. |
| Comedogenicity | Rare | Low comedogenic potential; pore clogging rarely reported in sensitive individuals. |
| Mild contact irritation | Rare | Occasional redness or stinging, usually in sensitive or compromised skin. |
| Mild skin irritation or stinging | Uncommon | Typically transient, more likely at higher concentrations or on sensitive skin. |
| Redness (erythema) | Uncommon | Usually mild and resolves with discontinuation or reduced frequency. |
| Contact dermatitis or allergic reaction | Rare | Patch testing recommended for those with sensitive or reactive skin. |
| Paradoxical hyperpigmentation | Very rare | Theoretical concern linked to hydroquinone-type compounds; not well documented for alpha arbutin at typical use levels. |
| Dryness and flaking | Common | Often occurs during the initial adjustment period as skin acclimates. |
| Erythema (redness) | Common | Mild irritation and redness, especially at higher concentrations. |
| Stinging or burning sensation | Common | Typically transient upon application. |
| Increased photosensitivity | Common | Skin becomes more susceptible to UV damage; daytime sunscreen recommended. |
| Peeling or scaling | Uncommon | More likely with frequent use or higher strengths. |
| Retinoid dermatitis | Uncommon | Contact dermatitis-like reaction with persistent irritation. |
| Purging (temporary breakouts) | Uncommon | Transient acne flare attributed to accelerated cell turnover. |
| Severe allergic contact dermatitis | Rare | Hypersensitivity reaction requiring discontinuation. |
| Hyperpigmentation or hypopigmentation | Rare | More frequently reported in darker skin tones following irritation. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| C13-15 Alkane Emollient / solvent | C13-15 Alkane is a lightweight, plant-derived (often sugarcane-based) liquid hydrocarbon used as an emollient and spreading agent in skincare. It softens skin, improves product texture, and serves as a sustainable alternative to silicones and mineral oil. |
| Diethylhexyl Carbonate Emollient / solvent | Diethylhexyl Carbonate is a lightweight synthetic ester (dialkyl carbonate) used as an emollient and solvent in skincare and cosmetics. It imparts a smooth, dry, non-greasy skin feel and helps dissolve and spread other ingredients such as UV filters and active oils. |
| Behenyl Alcohol Emollient / Thickener | Behenyl alcohol is a fatty alcohol derived from behenic acid that functions as an emollient, thickening agent, and emulsion stabilizer in cosmetic and skincare formulations. It helps soften the skin and improve product texture and stability. |
| Caprylic/Capric Triglyceride Emollient / skin-conditioning agent | Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active. |
| Alpha-Arbutin Key active Skin-brightening agent | Alpha arbutin is a naturally derived hydroquinone derivative that inhibits tyrosinase, reducing melanin production. It is used to address hyperpigmentation, dark spots, and uneven skin tone. |
| Retinol Key active Vitamin A derivative / anti-aging active | Retinol is a vitamin A derivative that converts to retinoic acid in the skin, promoting cell turnover and stimulating collagen synthesis. It is widely used to address fine lines, photoaging, and acne. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Butylene Glycol Humectant / solvent | Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations. |
| Carbomer Thickener / gelling agent | Carbomer is a synthetic high-molecular-weight polymer of acrylic acid used to thicken, stabilize, and control the viscosity of gels, creams, and lotions. It functions as a formulation aid rather than a therapeutic active. |
| Polysorbate 20 Emulsifier / solubilizer | Polysorbate 20 is a nonionic surfactant derived from sorbitol and lauric acid, used in skincare to solubilize fragrances and essential oils and to stabilize oil-in-water emulsions. It functions primarily as a formulation aid rather than a treatment active. |
| Palmitoyl Tripeptide-1 Key active Signal peptide / anti-aging active | Palmitoyl Tripeptide-1 is a synthetic palmitoylated peptide (sequence Gly-His-Lys) used in cosmetics to signal fibroblasts and support collagen and extracellular matrix synthesis. It is commonly combined with other peptides in anti-aging and firming formulations. |
| Palmitoyl Tetrapeptide-7 Key active Anti-aging signal peptide | Palmitoyl Tetrapeptide-7 is a palmitoylated synthetic peptide used in cosmetic formulations, primarily marketed to help reduce inflammatory signaling and support a more even, firmer skin appearance. It is commonly paired with other peptides such as Palmitoyl Tripeptide-1 in anti-aging products. |
| Methyl Glucose Sesquistearate Emulsifier / emollient | Methyl Glucose Sesquistearate is a glucose-derived nonionic emulsifier used to stabilize oil-in-water emulsions and impart a smooth, conditioning skin feel. It is considered mild and is widely used as a formulation base ingredient rather than a treatment active. |
| Ascorbyl Glucoside Key active Antioxidant / vitamin C derivative | Ascorbyl Glucoside is a stable, water-soluble vitamin C derivative that is enzymatically converted to ascorbic acid in the skin, providing antioxidant protection and supporting collagen synthesis and skin brightening. It is generally considered milder and more stable than pure L-ascorbic acid. |
| Retinaldehyde Key active Retinoid (vitamin A derivative) | Retinaldehyde (retinal) is a vitamin A derivative that is converted to retinoic acid in the skin, used to promote cell turnover, improve photoaging, and reduce acne. It is considered more potent than retinol but generally better tolerated than prescription retinoic acid. |
| Pentaerythrityl Distearate Emollient / thickener | Pentaerythrityl Distearate is an ester of pentaerythritol and stearic acid used as an emollient, viscosity-modifier and texture enhancer in cosmetic formulations. It imparts a smooth, conditioning feel and helps stabilize emulsions. |
| Dipotassium Glycyrrhizate Key active Anti-inflammatory/soothing agent | Dipotassium glycyrrhizate is a water-soluble salt derived from licorice root (glycyrrhizic acid) used in skincare for its anti-inflammatory, soothing, and antioxidant properties. It is commonly added to formulations to calm irritation, redness, and sensitivity. |
| Pentylene Glycol Humectant / solvent / preservative-booster | Pentylene glycol is a glycol used in cosmetics as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, helping reduce reliance on traditional preservatives. It improves skin hydration and aids the delivery and stability of other ingredients. |
| PolyacrylateCrosspolymer-6 Texture enhancer / sensory modifier | Polyacrylate Crosspolymer-6 is a synthetic crosslinked polymer used in skincare formulations as a thickening, stabilizing, and film-forming agent that imparts a light, smooth, gel-like sensory feel. It is a formulation aid rather than a treatment active. |
| 4-T-Butylcyclohexanol Key active Soothing/anti-irritant agent (TRPV1 antagonist) | 4-T-Butylcyclohexanol is a synthetic cyclohexanol derivative used in skincare to reduce sensory irritation and redness by inhibiting the TRPV1 receptor. It is commonly added to formulations for sensitive or reactive skin to counteract irritation from other actives. |
| Xanthan Gum Thickener/stabilizer | Xanthan gum is a polysaccharide produced by bacterial fermentation, used in skincare as a thickening, gelling, and emulsion-stabilizing agent. It improves product texture and suspension of ingredients without contributing active treatment effects. |
| Pentaerythrityl Tetra-Di-T-ButylHydroxyhydrocinnamate Antioxidant / stabilizer | Pentaerythrityl Tetra-Di-T-ButylHydroxyhydrocinnamate is a hindered phenolic antioxidant used in cosmetic formulations to protect oils, fats and other ingredients from oxidative degradation, thereby extending product stability and shelf life. It is also known by trade names such as Tinogard TT. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Trisodium Ethylenediamine Disuccinate Chelating agent | Trisodium Ethylenediamine Disuccinate (Trisodium Ethylenediamine Disuccinate, or HEDTA-type biodegradable chelator) is a biodegradable chelating agent used to bind metal ions in cosmetic formulations. By sequestering trace metals, it helps stabilize products, prevent discoloration and rancidity, and enhance the efficacy of preservatives and antioxidants. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Sodium Metabisulfite Antioxidant/preservative | Sodium metabisulfite is an inorganic salt used in cosmetic and topical formulations primarily as an antioxidant and preservative to prevent oxidation and discoloration of products. It releases sulfur dioxide, which helps stabilize sensitive ingredients. |
| Sodium Lactate Humectant / NMF component | Sodium lactate is the sodium salt of lactic acid and a key component of skin's natural moisturizing factor (NMF), used to hydrate the skin and buffer formulation pH. It also has mild exfoliating and humectant properties that help maintain skin moisture and barrier function. |
| Sodium Hydroxide pH adjuster | Sodium hydroxide (lye) is a strong alkaline compound used in small amounts to adjust and stabilize the pH of cosmetic formulations. At regulated low concentrations in finished products it is considered safe, though it is corrosive in concentrated form. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.