Acetyl Tetrapeptide-22 is a synthetic biomimetic peptide marketed to protect skin cells from stress (notably UV and oxidative damage) and to support skin barrier resilience. It is used in cosmetic formulations at low concentrations as a supportive anti-aging and protective active.
| Reported effect | How often | Notes |
|---|---|---|
Mild transient irritation or redness | Rare | Possible at application site, generally with leave-on products |
Allergic contact dermatitis or sensitization | Very rare | Reported only anecdotally; peptides are generally low-sensitizing |
Stinging or tingling sensation | Rare | Usually formulation-related rather than the peptide itself |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.