Polyhydroxy acids (PHAs) such as gluconolactone and lactobionic acid are larger-molecule chemical exfoliants that gently remove dead skin cells while providing humectant and antioxidant benefits. Their larger molecular size limits skin penetration, making them milder than AHAs and suitable for sensitive skin.
| Reported effect | How often | Notes |
|---|---|---|
Mild stinging or tingling | Common | Transient sensation on application, usually resolves quickly. |
Skin dryness or flaking | Uncommon | More likely with frequent use or higher concentrations. |
Redness or irritation | Uncommon | Typically mild; less frequent than with AHAs due to larger molecule size. |
Increased photosensitivity | Rare | Less pronounced than AHAs, but sun protection is still advised. |
Allergic contact dermatitis | Very rare | Isolated reports; discontinue if persistent reaction occurs. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.