Niacinamide (nicotinamide) is a water-soluble form of vitamin B3 that supports the skin barrier by promoting ceramide synthesis, helps reduce hyperpigmentation, regulates sebum, and has anti-inflammatory properties. At 3% it is a moderate concentration commonly used for general barrier support and tone improvement.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient flushing or warmth | Uncommon | More associated with higher concentrations or oral niacin; topical flushing is rare. |
| Stinging or tingling on application | Uncommon | Usually mild and resolves quickly, more likely on compromised or sensitive skin. |
| Erythema (redness) | Uncommon | Generally minor and temporary. |
| Allergic contact dermatitis | Rare | Sensitization to niacinamide is infrequently reported. |
| Irritation when combined with low-pH actives | Rare | Theoretical conversion to nicotinic acid under certain conditions may cause transient flushing. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
Peer-reviewed papers on this ingredient, via PubMed.