Disodium Flavin Adenine Dinucleotide (FAD) is the water-soluble disodium salt of the riboflavin-derived coenzyme, functioning as a redox cofactor and antioxidant in skincare formulations. It is used for its potential to support cellular energy metabolism and protect against oxidative stress.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient irritation or stinging | Rare | Occasional sensitivity at application site, typically mild and self-limiting. |
| Contact dermatitis / allergic reaction | Very rare | Isolated reports; patch testing advised for sensitive skin. |
| Skin discoloration or yellow staining | Rare | Riboflavin derivatives are intensely yellow and may temporarily tint skin or fabric. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.