Palmitoyl Glycine is a lipidated amino acid derivative used in cosmetic formulations for its skin-conditioning and antimicrobial-supporting properties, and is often included in anti-aging blends to support skin barrier and texture. It combines the amino acid glycine with palmitic acid to improve lipid solubility and skin compatibility.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient irritation or redness | Rare | Generally well tolerated; occasional mild irritation reported in sensitive skin |
| Contact allergy or sensitization | Very rare | Isolated reports; uncommon for amino acid–fatty acid conjugates |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.