Nykaa · 🇮🇳 India

Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream

44 ingredients
What's in it

Below is every ingredient in Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.

Suitability at a glance — for Indian skin

🍄 May trigger fungal acne
6 ingredient(s) can feed Malassezia — relevant in humid Indian weather
Pore-clogging risk: Moderate
Highest comedogenic rating 2/5 — matters for oily, acne-prone skin
Contains fragrance / allergens
Parfum
Contains drying alcohol
Alcohol Denat
Pregnancy: use caution
Retinyl Palmitate — discuss with a doctor

Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.

Your questions, answered from the ingredient list

Is Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream fungal-acne safe?
Based on its listed ingredients, Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream contains 6 ingredient(s) reported to feed Malassezia (the yeast behind fungal acne): Ethylhexyl Stearate, Polysorbate 20, Retinyl Palmitate, Sorbitan Laurate, Sorbitan Stearate. If you are fungal-acne prone, you may want to avoid these.
Does Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream contain fragrance?
Yes — Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream lists Parfum, which are fragrance ingredients or EU-declared allergens. Relevant if your skin is sensitive or reactive.
Will Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream clog pores?
The highest comedogenic rating among its listed ingredients is 2/5 (moderate). Comedogenicity matters most for oily, acne-prone skin in humid Indian weather; it is a property of ingredients in lab tests, not a guarantee either way.
Is Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream safe to use in pregnancy?
Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream contains 1 ingredient(s) commonly flagged for caution in pregnancy in published guidance: Retinyl Palmitate. Discuss with your doctor before using it while pregnant or breastfeeding.
Does Dermistry Anti Aging Repair Protect Intense Nourishing Night Cream contain drying alcohol?
Yes — it lists Alcohol Denat, volatile alcohol(s) that can dehydrate the skin barrier with frequent use.

Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.

Key actives

Tocopheryl Acetate
Antioxidant

Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier.

Ascorbyl Glucoside
Antioxidant / vitamin C derivative

Ascorbyl Glucoside is a stable, water-soluble vitamin C derivative that is enzymatically converted to ascorbic acid in the skin, providing antioxidant protection and supporting collagen synthesis and skin brightening. It is generally considered milder and more stable than pure L-ascorbic acid.

Retinyl Palmitate
Antioxidant / retinoid (vitamin A derivative)

Retinyl palmitate is an ester of retinol and palmitic acid used as a vitamin A source and antioxidant in skincare. It is converted in the skin to retinol and then retinoic acid, offering milder anti-aging and skin-conditioning effects than stronger retinoids.

Panax Ginseng Root Extract
Antioxidant / skin-conditioning

Panax Ginseng Root Extract is a botanical extract rich in ginsenosides and polysaccharides used in skincare for its antioxidant, anti-inflammatory, and circulation-supporting properties. It is often included to promote a brighter, more revitalized appearance and to help defend against oxidative stress.

Dimethylmethoxy Chromanol
Antioxidant

Dimethylmethoxy Chromanol is a synthetic chroman-derived antioxidant (a vitamin E-related molecule) used in cosmetic formulations to neutralize free radicals and protect skin and product stability against oxidative damage. It is marketed for both lipophilic and hydrophilic environments, offering broad-spectrum protection against reactive oxygen and nitrogen species.

Morus Alba Leaf Extract
Skin-brightening antioxidant

Morus alba (white mulberry) leaf extract is a botanical ingredient rich in flavonoids and polyphenols, used in skincare for its antioxidant and tyrosinase-inhibiting properties that may help reduce hyperpigmentation. It is typically incorporated as a functional active in brightening and protective formulations.

Side effects reported in research

Aggregated from the active ingredients in this product.

Reported effectHow oftenNotes
Irritation or sensitivityVery rarePurified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water.
Transepidermal water loss aggravation in compromised skinRareEvaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent.
Mild transient stinging or irritationUncommonMore likely at high concentrations or on compromised/broken skin.
Tacky or sticky skin feelCommonA cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations.
Contact dermatitis or allergic reactionRareTrue allergy to glycerin is uncommon; patch-test positivity is infrequent.
Skin dehydration in very low humidityRareIn very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive.
Allergic contact dermatitisRareReported infrequently; shea butter has low allergenic potential despite tree-nut origin.
Comedogenicity/acne aggravationUncommonMay contribute to clogged pores or breakouts in acne-prone or oily skin due to its occlusive, lipid-rich nature.
Skin irritationRareMild irritation or redness possible, generally in sensitive individuals.
Mild skin irritationRareOccasional transient redness or stinging, typically in sensitive skin.
ComedogenicityRareLow pore-clogging potential; rarely associated with breakouts in acne-prone individuals.
Mild skin irritation or rednessRareGenerally considered non-irritating; occasional mild reactions reported.
Clogged pores / comedogenic-related breakoutsUncommonOften anecdotal; dimethicone is largely regarded as non-comedogenic but may trap debris if skin is not cleansed well.
Eye irritation on accidental contactRareTransient stinging or discomfort if product enters the eyes.

Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.

Full ingredient breakdown

IngredientWhat it does
Aqua
Solvent / vehicle
Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery.
Glycerin
Humectant
Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations.
Butyrospermum Parkii Butter
Emollient/occlusive
Butyrospermum Parkii Butter (shea butter) is a plant-derived fat used in skincare as an emollient and occlusive agent to soften skin and reduce transepidermal water loss. It is rich in fatty acids and unsaponifiables that condition and help maintain the skin barrier.
Sorbitan Stearate
Emulsifier / surfactant
Sorbitan stearate is a non-ionic emulsifier derived from sorbitol and stearic acid, used to stabilize oil-in-water emulsions and improve texture in creams and lotions. It functions as a formulation aid rather than a therapeutic active.
Dimethicone
Emollient/occlusive (silicone)
Dimethicone is a silicone-based polymer used in skincare to soften skin, smooth texture, and form a breathable protective barrier that reduces transepidermal water loss. It is widely used as a base/formulation ingredient rather than a therapeutic active.
Cetearyl Alcohol
Emollient/emulsifier
Cetearyl alcohol is a fatty alcohol blend (cetyl and stearyl alcohol) used in skincare as an emollient, emulsion stabilizer, and thickening agent. It helps soften skin and keep oil and water phases blended in creams and lotions.
Caprylic/Capric Triglyceride
Emollient / skin-conditioning agent
Caprylic/Capric Triglyceride is a lightweight emollient derived from coconut or palm oil and glycerin, used to soften skin, improve spreadability, and act as a solvent for oil-soluble ingredients. It is well-tolerated and serves primarily as a base ingredient rather than an active.
Ethylhexyl Stearate
Emollient
Ethylhexyl Stearate is an ester of 2-ethylhexanol and stearic acid used as an emollient and skin-conditioning agent. It imparts a smooth, lightweight feel and helps soften skin and improve product spreadability.
Polyacrylamide
Thickener/film-former
Polyacrylamide is a synthetic polymer used in cosmetics primarily as a thickening agent, film former, and stabilizer that improves texture and viscosity of formulations. It is considered a base/formulation ingredient rather than a treatment active.
Butylene Glycol
Humectant / solvent
Butylene glycol is a small diol commonly used in skincare as a humectant, solvent, and viscosity-reducing agent that helps dissolve other ingredients and improve skin feel. It is widely regarded as safe and non-sensitizing for the majority of users at cosmetic concentrations.
Phenoxyethanol
Preservative
Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment.
C13-14 Isoparaffin
Emollient/thickener
C13-14 Isoparaffin is a synthetic hydrocarbon used in skincare primarily as an emollient and as a thickening or gelling agent, often paired with polyacrylamide-based systems to stabilize emulsions. It helps improve spreadability and texture but provides no active treatment benefit.
Alcohol Denat
Solvent/penetration enhancer
Alcohol Denat (denatured ethanol) is a volatile solvent used in skincare to dissolve other ingredients, improve product spreadability and absorption, and create a quick-drying, lightweight feel. It is a formulation aid rather than a therapeutic active.
Dimethiconol
Emollient/silicone conditioning agent
Dimethiconol is a silicone-based polymer used in skincare and haircare to provide smoothing, conditioning, and a soft, non-greasy emollient feel. It forms a thin, breathable film that reduces moisture loss and improves spreadability of formulations.
Tribehenin
Emollient/emulsifier
Tribehenin is the triester of glycerin and behenic acid (a long-chain fatty acid) used in cosmetics as a skin-conditioning emollient, emulsion stabilizer, and viscosity-increasing agent. It helps soften skin and improve the texture and spreadability of creams and lotions.
Sucrose Cocoate
Emollient/surfactant
Sucrose Cocoate is a sugar-based ester of sucrose and coconut fatty acids used as a mild nonionic surfactant, emulsifier, and emollient in skincare and cleansing formulations. It helps condition the skin and stabilize emulsions while being relatively gentle.
Parfum
Fragrance
Parfum (fragrance) is a blend of aromatic compounds added to cosmetic products to impart a pleasant scent or mask the base odor of other ingredients. It serves a sensory/formulation purpose rather than providing any skin benefit.
Methylparaben
Preservative
Methylparaben is a paraben-class antimicrobial preservative widely used in cosmetics and skincare to prevent microbial growth and extend product shelf life. It is effective primarily against fungi and yeasts, often combined with other parabens for broader protection.
Carbomer
Thickener / gelling agent
Carbomer is a synthetic high-molecular-weight polymer of acrylic acid used to thicken, stabilize, and control the viscosity of gels, creams, and lotions. It functions as a formulation aid rather than a therapeutic active.
Laureth-7
Emulsifier/surfactant
Laureth-7 is a polyethylene glycol ether of lauryl alcohol used in cosmetics as a nonionic surfactant, emulsifier, and solubilizer to stabilize formulations and disperse oils. It functions as a formulation aid rather than a therapeutic active.
Propylene Glycol
Humectant / solvent
Propylene glycol is a small glycol molecule widely used in skincare as a humectant, solvent, and penetration enhancer that helps attract water and dissolve other ingredients. It is considered a base/formulation ingredient rather than a therapeutic active.
Tocopheryl Acetate Key active
Antioxidant
Tocopheryl acetate is a stable, esterified form of vitamin E used in skincare as an antioxidant and conditioning agent. It is converted to active tocopherol in the skin, helping protect against oxidative stress and supporting the skin barrier.
Sodium Hyaluronate
Humectant / hydrator
Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid.
Ethylparaben
Preservative
Ethylparaben is a paraben-class antimicrobial preservative used to inhibit the growth of bacteria, yeast, and mold in cosmetic and skincare formulations. It is valued for its broad-spectrum efficacy and stability across a wide pH range.
Ascorbyl Glucoside Key active
Antioxidant / vitamin C derivative
Ascorbyl Glucoside is a stable, water-soluble vitamin C derivative that is enzymatically converted to ascorbic acid in the skin, providing antioxidant protection and supporting collagen synthesis and skin brightening. It is generally considered milder and more stable than pure L-ascorbic acid.
Dipropylene Glycol
Solvent/humectant
Dipropylene glycol is a clear, low-viscosity glycol used in cosmetics primarily as a solvent, humectant, and viscosity-reducing agent. It helps dissolve fragrances and other ingredients while contributing mild moisture-retention properties.
Retinyl Palmitate Key active
Antioxidant / retinoid (vitamin A derivative)
Retinyl palmitate is an ester of retinol and palmitic acid used as a vitamin A source and antioxidant in skincare. It is converted in the skin to retinol and then retinoic acid, offering milder anti-aging and skin-conditioning effects than stronger retinoids.
Xanthan Gum
Thickener/stabilizer
Xanthan gum is a polysaccharide produced by bacterial fermentation, used in skincare as a thickening, gelling, and emulsion-stabilizing agent. It improves product texture and suspension of ingredients without contributing active treatment effects.
Hydrolyzed Rice Protein
Conditioning agent / film-former
Hydrolyzed rice protein is a water-soluble blend of amino acids and peptides derived from rice, used in skincare and haircare to provide moisturizing, conditioning, and film-forming benefits that improve surface smoothness and hydration. It is primarily a cosmetic functional ingredient rather than a clinically active treatment.
Tetrasodium EDTA
Chelating agent
Tetrasodium EDTA is a chelating agent used in skincare formulations to bind metal ions, improving product stability, preserving efficacy, and enhancing the performance of preservatives and surfactants. It is a formulation aid rather than a therapeutic active.
Sorbitan Laurate
Emulsifier / surfactant
Sorbitan Laurate is a non-ionic emulsifier and surfactant derived from sorbitol and lauric acid, used to stabilize oil-in-water emulsions and improve texture in skincare formulations. It functions primarily as a base/formulation ingredient rather than a treatment active.
Potassium Hydroxide
pH adjuster / saponifying agent
Potassium hydroxide is a strong alkaline compound used in cosmetics to adjust pH and to saponify fatty acids in the production of liquid soaps and cleansers. At regulated low concentrations in finished products it is considered safe, functioning as a formulation aid rather than an active treatment.
Panax Ginseng Root Extract Key active
Antioxidant / skin-conditioning
Panax Ginseng Root Extract is a botanical extract rich in ginsenosides and polysaccharides used in skincare for its antioxidant, anti-inflammatory, and circulation-supporting properties. It is often included to promote a brighter, more revitalized appearance and to help defend against oxidative stress.
Dimethylmethoxy Chromanol Key active
Antioxidant
Dimethylmethoxy Chromanol is a synthetic chroman-derived antioxidant (a vitamin E-related molecule) used in cosmetic formulations to neutralize free radicals and protect skin and product stability against oxidative damage. It is marketed for both lipophilic and hydrophilic environments, offering broad-spectrum protection against reactive oxygen and nitrogen species.
Medicago Sativa Extract
Antioxidant / Skin conditioning
Medicago Sativa (alfalfa) Extract is a plant-derived ingredient rich in vitamins, amino acids, and antioxidants used in skincare to condition and protect skin. It is primarily included for its soothing and antioxidant properties rather than as a clinically proven dermatological active.
Polysorbate 20
Emulsifier / solubilizer
Polysorbate 20 is a nonionic surfactant derived from sorbitol and lauric acid, used in skincare to solubilize fragrances and essential oils and to stabilize oil-in-water emulsions. It functions primarily as a formulation aid rather than a treatment active.
Hydroxyethylcellulose
Thickener/viscosity modifier
Hydroxyethylcellulose is a non-ionic, water-soluble cellulose derivative used to thicken, stabilize, and adjust the texture of aqueous cosmetic formulations. It functions as a gelling and film-forming agent rather than providing a direct biological skin benefit.
Morus Alba Leaf Extract Key active
Skin-brightening antioxidant
Morus alba (white mulberry) leaf extract is a botanical ingredient rich in flavonoids and polyphenols, used in skincare for its antioxidant and tyrosinase-inhibiting properties that may help reduce hyperpigmentation. It is typically incorporated as a functional active in brightening and protective formulations.
Sodium Benzoate
Preservative
Sodium benzoate is a salt of benzoic acid used as a preservative in cosmetic and skincare formulations to inhibit the growth of bacteria, yeast, and fungi, particularly in acidic products. It is most effective at a pH below 5.
Tocopherol Key active
Antioxidant
Tocopherol (vitamin E) is a lipid-soluble antioxidant used in skincare to protect skin and formulations from oxidative damage caused by free radicals and UV exposure. It also functions as a skin-conditioning and emollient agent and can stabilize oils against rancidity.
Acetyl Dipeptide-1 Cetyl Ester Key active
Soothing peptide / sensory modulator
Acetyl Dipeptide-1 Cetyl Ester is a synthetic lipidated dipeptide used in cosmetics for its purported soothing and anti-irritant effects, thought to modulate sensory neuron signaling and reduce discomfort sensations. It is often included in products targeting sensitive or reactive skin.
Ethylhexylglycerin
Preservative booster / skin-conditioning agent
Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations.
Palmitoyl Tripeptide-1 Key active
Signal peptide / anti-aging active
Palmitoyl Tripeptide-1 is a synthetic palmitoylated peptide (sequence Gly-His-Lys) used in cosmetics to signal fibroblasts and support collagen and extracellular matrix synthesis. It is commonly combined with other peptides in anti-aging and firming formulations.
Palmitoyl Tetrapeptide-7 Key active
Anti-aging signal peptide
Palmitoyl Tetrapeptide-7 is a palmitoylated synthetic peptide used in cosmetic formulations, primarily marketed to help reduce inflammatory signaling and support a more even, firmer skin appearance. It is commonly paired with other peptides such as Palmitoyl Tripeptide-1 in anti-aging products.

Key active = does the main work. Ingredient explanations are drawn from public databases & literature.

From published literature

Peer-reviewed papers on the active ingredients in this product, via PubMed.

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