Acetyl Tetrapeptide-5 is a synthetic peptide used in cosmetics primarily to reduce periorbital puffiness and improve skin elasticity by inhibiting angiotensin-converting enzyme activity and reducing fluid accumulation and glycation. It is commonly found in eye creams and anti-aging formulations.
| Reported effect | How often | Notes |
|---|---|---|
Mild transient irritation or redness | Rare | Generally well tolerated at cosmetic concentrations; mild irritation may occur in sensitive individuals. |
Contact allergy or sensitization | Very rare | Few documented cases; peptide sensitization is uncommon. |
Stinging or tingling on application | Rare | Usually formulation-dependent and temporary. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.