Biotinyl-GHK is a biotin-conjugated tripeptide (glycyl-histidyl-lysine) used in skincare and haircare formulations, primarily marketed to support hair anchoring, scalp conditioning, and skin matrix renewal. The biotin moiety is intended to enhance lipophilicity and delivery of the GHK signaling peptide.
| Reported effect | How often | Notes |
|---|---|---|
Mild localized irritation or redness | Rare | Generally well tolerated; transient erythema possible at application site. |
Contact sensitization or allergic reaction | Very rare | Peptide-related hypersensitivity is uncommon but theoretically possible. |
Stinging or itching | Rare | Usually formulation-dependent and transient. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.