Sodium thiosulfate is a sulfur-containing salt used in topical formulations for its antioxidant and mild keratolytic properties, and it has been investigated for conditions such as calcinosis cutis and tinea versicolor. It can also act as a chelating and reducing agent in skincare preparations.
| Reported effect | How often | Notes |
|---|---|---|
Local skin irritation | Common | Stinging, burning, or redness at the application site, often transient. |
Dryness or scaling | Uncommon | Mild peeling from its keratolytic action. |
Contact dermatitis | Rare | Allergic or irritant reaction in sensitized individuals. |
Unpleasant sulfur-like odor sensitivity | Uncommon | Cosmetic complaint rather than a true adverse effect. |
Systemic effects | Very rare | Negligible with topical use; reported mainly with intravenous administration. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.