Below is every ingredient in The Derma Co. X Dr V Skin Renew Peptide Anti-Pollution Face Wash with Peptides & Niacinamide - 100 ml explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Tripeptide-1 (also known as Glycyl-L-Histidyl-L-Lysine, GHK) is a signaling peptide used in anti-aging formulations to support collagen and extracellular matrix production. It is studied for improving skin firmness, elasticity, and reducing the appearance of fine lines.
Palmitoyl Tripeptide-5 is a synthetic collagen-stimulating peptide that mimics the action of TGF-beta to support dermal collagen synthesis. It is used in topical formulations to help reduce the appearance of fine lines and improve skin firmness.
Salicylic acid is a lipid-soluble beta-hydroxy acid that exfoliates the skin surface and penetrates sebaceous pores to loosen and dissolve keratin and debris. It is widely used to treat acne, blackheads, and conditions involving thickened or scaly skin.
Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Irritation or sensitivity | Very rare | Purified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water. |
| Transepidermal water loss aggravation in compromised skin | Rare | Evaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent. |
| Skin irritation or dryness | Uncommon | More likely at higher concentrations or with prolonged contact, though milder than sulfates. |
| Eye irritation | Uncommon | Can cause stinging if formulations contact the eyes. |
| Allergic contact dermatitis | Rare | Sensitization reported infrequently in patch-test literature. |
| Mucosal irritation in oral products | Rare | Occasionally noted with toothpaste use in sensitive individuals. |
| Skin irritation | Rare | Mild redness or stinging, typically in sensitive individuals. |
| Contact dermatitis / allergic reaction | Very rare | Reported occasionally, often linked to residual acrylate monomers rather than the polymer itself. |
| Dryness or tightness | Uncommon | Film-forming action may cause a tight sensation in some users. |
| Clogged pores / comedogenicity | Rare | Generally considered low risk, but possible in occlusive formulations on acne-prone skin. |
| Skin or eye irritation | Uncommon | Mild stinging or irritation, more likely in concentrated or rinse-off products and around the eyes. |
| Cross-reactivity with related surfactants | Rare | Patch-test reactions may overlap with chemically related amphoteric or amine-containing surfactants. |
| Dryness or transient redness | Rare | More likely in compromised or very sensitive skin with frequent use. |
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Aqua Solvent / vehicle | Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery. |
| Sodium Lauroyl Sarcosinate Surfactant / cleansing agent | Sodium Lauroyl Sarcosinate is an amino acid-derived anionic surfactant used in cleansers, shampoos and toothpastes to provide gentle foaming and cleansing. It is generally considered milder than traditional sulfate surfactants. |
| Acrylates Copolymer Film-former / texture enhancer | Acrylates Copolymer is a synthetic polymer used in skincare and cosmetics primarily as a film-forming agent, viscosity modifier, and to improve product texture and wear. It helps control sebum, provides a smooth feel, and stabilizes formulations. |
| Cocamidopropyl Betaine Surfactant / foaming cleanser | Cocamidopropyl Betaine is an amphoteric surfactant derived from coconut oil and dimethylaminopropylamine, used in cleansers, shampoos, and body washes to provide gentle foaming, viscosity, and to reduce the harshness of stronger anionic surfactants. It is widely regarded as mild but is a recognized contact allergen. |
| Disodium Cocoamphodiacetate Mild amphoteric surfactant / cleansing agent | Disodium Cocoamphodiacetate is a coconut-derived amphoteric surfactant used in cleansers, shampoos, and body washes to provide gentle cleansing, foam, and to reduce the irritation potential of harsher anionic surfactants. It is valued for mildness in baby and sensitive-skin formulations. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
| Sodium Hydroxide pH adjuster | Sodium hydroxide (lye) is a strong alkaline compound used in small amounts to adjust and stabilize the pH of cosmetic formulations. At regulated low concentrations in finished products it is considered safe, though it is corrosive in concentrated form. |
| Dextran Polysaccharide film-former / humectant | Dextran is a branched glucose polysaccharide produced by bacterial fermentation, used in skincare as a hydrating film-forming agent and stabilizer that can improve texture and aid in carrying other ingredients. It is generally considered well tolerated and biocompatible. |
| Tripeptide-1 Key active Signal peptide / collagen-stimulating active | Tripeptide-1 (also known as Glycyl-L-Histidyl-L-Lysine, GHK) is a signaling peptide used in anti-aging formulations to support collagen and extracellular matrix production. It is studied for improving skin firmness, elasticity, and reducing the appearance of fine lines. |
| Palmitoyl Tripeptide-5 Key active Anti-aging peptide | Palmitoyl Tripeptide-5 is a synthetic collagen-stimulating peptide that mimics the action of TGF-beta to support dermal collagen synthesis. It is used in topical formulations to help reduce the appearance of fine lines and improve skin firmness. |
| Sodium Benzoate Preservative | Sodium benzoate is a salt of benzoic acid used as a preservative in cosmetic and skincare formulations to inhibit the growth of bacteria, yeast, and fungi, particularly in acidic products. It is most effective at a pH below 5. |
| Methoxycinnamidopropyl Hydroxysultaine Surfactant / antistatic agent | Methoxycinnamidopropyl Hydroxysultaine is an amphoteric (zwitterionic) surfactant derived from cinnamic acid, used in cleansing and conditioning formulations as a mild detergent, foam booster, and antistatic agent. It is considered a functional formulation ingredient rather than a treatment active. |
| Salicylic Acid Key active Beta-hydroxy acid (BHA) exfoliant / keratolytic | Salicylic acid is a lipid-soluble beta-hydroxy acid that exfoliates the skin surface and penetrates sebaceous pores to loosen and dissolve keratin and debris. It is widely used to treat acne, blackheads, and conditions involving thickened or scaly skin. |
| Betaine Humectant / osmolyte | Betaine is a naturally derived amino acid derivative (trimethylglycine) used in skincare as a humectant and osmoprotectant that attracts and retains moisture while helping stabilize skin barrier function. It also improves the texture and mildness of formulations. |
| Sodium Gluconate Chelating agent / skin-conditioning | Sodium gluconate is the sodium salt of gluconic acid used in skincare primarily as a chelating agent to bind metal ions and stabilize formulations, with secondary humectant and skin-conditioning properties. It is generally considered a base/formulation ingredient rather than an active treatment. |
| Centella Asiatica Extract Key active Soothing/antioxidant active | Centella Asiatica Extract is a plant-derived ingredient rich in triterpenoids (asiaticoside, madecassoside, asiatic and madecassic acids) used to calm inflammation, support wound healing, and strengthen the skin barrier. It is also valued for antioxidant and collagen-supporting properties in topical formulations. |
| Aloe Barbadensis Leaf Extract Soothing/moisturizing agent | Aloe Barbadensis Leaf Extract is derived from the aloe vera plant and is used in skincare for its hydrating, soothing, and mild anti-inflammatory properties. It is commonly included as a supportive base ingredient rather than a primary treatment active. |
| Biosaccharide Gum-4 Skin-conditioning / soothing agent | Biosaccharide Gum-4 is a polysaccharide derived from microbial fermentation of plant sugars, used in topical formulations as a film-forming humectant and soothing agent. It is reported to help reduce visible signs of irritation and provide a smoothing, hydrating feel to the skin. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.