Glycine is a small amino acid used in skincare as a humectant and conditioning agent, supporting skin hydration and acting as a building block for collagen and natural moisturizing factor. It is generally considered well-tolerated and is often included as part of moisturizing or barrier-support formulations.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient irritation or stinging | Rare | Possible on compromised or sensitive skin, usually minor and temporary |
| Contact allergic reaction | Very rare | Allergic sensitization to glycine is uncommon and seldom reported |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.