Below is every ingredient in The Derma Co 2 Salicylic Acid Serum For Acne Acne Marks explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%.
Salicylic acid is a lipid-soluble beta-hydroxy acid that exfoliates the skin surface and penetrates sebaceous pores to loosen and dissolve keratin and debris. It is widely used to treat acne, blackheads, and conditions involving thickened or scaly skin.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Irritation or sensitivity | Very rare | Purified water itself is essentially inert; rare reactions are attributable to contaminants or accompanying ingredients rather than water. |
| Transepidermal water loss aggravation in compromised skin | Rare | Evaporation of water from products may transiently increase dryness in very compromised skin barriers if occlusives are absent. |
| Mild skin irritation | Rare | Occasional transient redness or stinging, typically at higher concentrations or on compromised skin. |
| Allergic contact dermatitis | Very rare | Isolated case reports of sensitization; considered uncommon compared to related glycols. |
| Enhanced irritation from co-formulated actives | Uncommon | By increasing penetration, it may intensify the effects or irritation potential of other ingredients. |
| Eye irritation | Rare | Can occur with accidental contact in concentrated form. |
| Mild transient flushing or redness | Uncommon | More likely at higher concentrations or in sensitive skin; usually subsides quickly. |
| Tingling, stinging, or burning sensation | Uncommon | Often associated with higher percentages or compromised barrier. |
| Contact irritation or itching | Rare | Generally dose-dependent and resolves with discontinuation. |
| Mild transient stinging or irritation | Uncommon | More likely at high concentrations or on compromised/broken skin. |
| Tacky or sticky skin feel | Common | A cosmetic sensation rather than an adverse reaction, more noticeable at higher concentrations. |
| Contact dermatitis or allergic reaction | Rare | True allergy to glycerin is uncommon; patch-test positivity is infrequent. |
| Skin dehydration in very low humidity | Rare | In very dry environments humectants may draw water from deeper skin layers if not paired with an occlusive. |
| Skin dryness and peeling | Common | Mild flaking or tightness, especially with frequent use or higher concentrations. |
| Stinging, burning, or irritation | Common | Transient sensation on application, often more pronounced on sensitive or compromised skin. |
| Erythema (redness) | Common | Temporary redness at the application site. |
| Contact dermatitis | Uncommon | Localized inflammation; can be irritant or, less often, allergic in nature. |
| Increased photosensitivity | Uncommon | Exfoliation may heighten sun sensitivity; sunscreen use is advised. |
| Salicylism (systemic toxicity) | Rare | Reported with extensive application over large body areas, high concentrations, or occlusion; symptoms include nausea, tinnitus, and dizziness. |
| Severe allergic reaction | Very rare | Hypersensitivity reactions such as significant swelling or hives. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| Aqua Solvent / vehicle | Aqua (water) is the most common base ingredient in skincare formulations, serving as a solvent that dissolves water-soluble components and forms the medium for emulsions. It has no direct treatment activity and primarily contributes to texture, spreadability, and product delivery. |
| 1, 3-Propanediol Humectant/solvent | 1,3-Propanediol is a naturally derived (often corn-based) humectant and solvent used in cosmetics to hydrate skin, enhance ingredient penetration, and improve product texture. It is widely considered a gentle, well-tolerated formulation ingredient. |
| Ethoxydiglycol Solvent / penetration enhancer | Ethoxydiglycol (diethylene glycol monoethyl ether) is a glycol ether used in cosmetic formulations primarily as a solvent and viscosity reducer that helps dissolve active ingredients and improve their skin penetration. It is considered a formulation aid rather than a therapeutic active. |
| Niacinamide Key active Cell-communicating / barrier-repair active | Niacinamide (vitamin B3) is a water-soluble active that supports the skin barrier, regulates sebum, brightens hyperpigmentation, and reduces inflammation. It is widely tolerated across skin types and used in concentrations commonly ranging from 2% to 10%. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Salicylic Acid Key active Beta-hydroxy acid (BHA) exfoliant / keratolytic | Salicylic acid is a lipid-soluble beta-hydroxy acid that exfoliates the skin surface and penetrates sebaceous pores to loosen and dissolve keratin and debris. It is widely used to treat acne, blackheads, and conditions involving thickened or scaly skin. |
| Dimethyl Isosorbide Solvent / penetration enhancer | Dimethyl Isosorbide (DMI) is a small, polar solvent derived from isosorbide used in cosmetic formulations to dissolve active ingredients and enhance their penetration into the skin. It functions as a vehicle and carrier rather than a therapeutic active itself. |
| Pentylene Glycol Humectant / solvent / preservative-booster | Pentylene glycol is a glycol used in cosmetics as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, helping reduce reliance on traditional preservatives. It improves skin hydration and aids the delivery and stability of other ingredients. |
| Methylpropanediol Humectant/solvent | Methylpropanediol is a small glycol-type ingredient used in skincare as a humectant and solvent that helps hydrate skin and enhance the penetration of other actives. It also contributes to product texture and can support preservative efficacy. |
| Pullulan Film-forming agent / texturizer | Pullulan is a naturally derived polysaccharide produced by fermentation of starch by the fungus Aureobasidium pullulans. In skincare it forms a thin, breathable film on the skin, providing a temporary tightening or smoothing effect and helping to stabilize formulations. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| Xanthan Gum Thickener/stabilizer | Xanthan gum is a polysaccharide produced by bacterial fermentation, used in skincare as a thickening, gelling, and emulsion-stabilizing agent. It improves product texture and suspension of ingredients without contributing active treatment effects. |
| Hordeum Vulgare Extract Soothing/antioxidant botanical extract | Hordeum Vulgare (barley) Extract is a plant-derived ingredient used in skincare for its antioxidant, conditioning, and soothing properties, often as a supportive botanical rather than a primary treatment active. It contains polyphenols, vitamins, and polysaccharides that may help moisturize and protect skin. |
| Methyl Gluceth-20 Humectant/moisturizer | Methyl Gluceth-20 is a water-soluble humectant derived from glucose and methyl glucose, used to attract and retain moisture in skincare and cosmetic formulations. It also functions as a skin-conditioning agent and helps improve product texture and spreadability. |
| Algin Thickener/film-former | Algin (sodium alginate) is a polysaccharide derived from brown seaweed used in skincare as a thickening, gelling, and film-forming agent. It helps stabilize emulsions and provides a hydrating, smooth texture, commonly featured in peel-off masks. |
| PEG-40 Hydrogenated Castor Oil Solubilizer/emulsifier | PEG-40 Hydrogenated Castor Oil is a nonionic surfactant derived from hydrogenated castor oil reacted with ethylene oxide, widely used to dissolve fragrances and oils into water-based formulations and to stabilize emulsions. It functions as a base/formulation ingredient rather than a treatment active. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Sodium Hydroxide pH adjuster | Sodium hydroxide (lye) is a strong alkaline compound used in small amounts to adjust and stabilize the pH of cosmetic formulations. At regulated low concentrations in finished products it is considered safe, though it is corrosive in concentrated form. |
| Trisodium Ethylenediamine Disuccinate Chelating agent | Trisodium Ethylenediamine Disuccinate (Trisodium Ethylenediamine Disuccinate, or HEDTA-type biodegradable chelator) is a biodegradable chelating agent used to bind metal ions in cosmetic formulations. By sequestering trace metals, it helps stabilize products, prevent discoloration and rancidity, and enhance the efficacy of preservatives and antioxidants. |
| Tris(Tetramethylhydroxypiperidinol) Citrate Antioxidant / chelating stabilizer | Tris(Tetramethylhydroxypiperidinol) Citrate is a hindered amine (HALS-type) antioxidant and metal-chelating agent used in skincare to protect formulations from oxidative degradation and to help neutralize free radicals. It functions primarily as a stabilizer and secondary antioxidant rather than a primary treatment active. |
| Propylene Glycol Humectant / solvent | Propylene glycol is a small glycol molecule widely used in skincare as a humectant, solvent, and penetration enhancer that helps attract water and dissolve other ingredients. It is considered a base/formulation ingredient rather than a therapeutic active. |
| Citric Acid pH adjuster / AHA exfoliant | Citric acid is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formulation pH and as a chelating agent, and at higher concentrations as a mild chemical exfoliant. It can promote surface cell turnover and is sometimes included in antioxidant or brightening products. |
| Calcium Chloride Viscosity/texture modifier & astringent | Calcium chloride is an inorganic salt used in skincare primarily to adjust viscosity, act as a mild astringent, and serve as a source of calcium ions in formulations. It is generally considered a functional/formulation ingredient rather than a therapeutic active. |
| Sodium Benzoate Preservative | Sodium benzoate is a salt of benzoic acid used as a preservative in cosmetic and skincare formulations to inhibit the growth of bacteria, yeast, and fungi, particularly in acidic products. It is most effective at a pH below 5. |
| Potassium Sorbate Preservative | Potassium sorbate is the potassium salt of sorbic acid, used as a mild preservative to inhibit mold, yeast, and some bacterial growth in cosmetic formulations. It is most effective at acidic pH and is often combined with other preservatives for broad-spectrum protection. |
| Ethylhexylglycerin Preservative booster / skin-conditioning agent | Ethylhexylglycerin is a multifunctional glyceryl ether used in cosmetics primarily as a preservative-enhancing agent and emollient, often paired with phenoxyethanol to broaden antimicrobial efficacy. It also acts as a deodorizing agent and humectant in skincare formulations. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.