Below is every ingredient in Dr Sheth S Non Irritating Ceramide 10 Vitamin C Ampoule Serum 10 Ml explained, its standout actives, and the side effects reported in research for those actives — analysed for Indian skin.
Flags derived from the ingredient list using dermatology reference data (fungal-acne substrate, comedogenicity, EU allergens). General guidance, not a diagnosis.
Answers are derived from the printed ingredient list and dermatology reference data — general guidance, not a diagnosis or a therapeutic claim.
Gluconolactone is a polyhydroxy acid that gently exfoliates the skin surface, provides antioxidant and humectant benefits, and is often considered milder than alpha hydroxy acids. It is well tolerated, including by sensitive skin, due to its larger molecular size and slower penetration.
3-O-Ethyl Ascorbic Acid is a stable, water-soluble ethylated derivative of vitamin C that converts to ascorbic acid in the skin, providing antioxidant protection and supporting collagen synthesis and pigmentation control. It is valued for greater stability than pure L-ascorbic acid while delivering similar brightening and anti-aging benefits.
Houttuynia Cordata extract is a botanical ingredient rich in flavonoids and polyphenols, used in skincare for its antioxidant, anti-inflammatory, and soothing properties. It is often included in formulations targeting sensitive, acne-prone, or irritated skin.
L-Ascorbic Acid is the biologically active form of vitamin C used topically as a potent antioxidant that helps neutralize free radicals, supports collagen synthesis, and can reduce hyperpigmentation. Its efficacy depends on low pH (typically below 3.5) and stable formulation, as it readily oxidizes when exposed to light, air, and heat.
Ferulic acid is a plant-derived phenolic antioxidant that neutralizes free radicals and helps protect skin from UV-induced oxidative damage. It is frequently combined with vitamins C and E to enhance their stability and photoprotective effect.
Gluconolactone is a polyhydroxy acid that gently exfoliates the skin surface, provides antioxidant and humectant benefits, and is often considered milder than alpha hydroxy acids. It is well tolerated, including by sensitive skin, due to its larger molecular size and slower penetration.
Aggregated from the active ingredients in this product.
| Reported effect | How often | Notes |
|---|---|---|
| Mild transient stinging or tingling | Common | Brief sensation on application, particularly at higher concentrations or on compromised skin. |
| Mild erythema (redness) | Uncommon | Usually temporary and resolves shortly after use. |
| Dryness or flaking | Uncommon | Related to its exfoliating action, more likely with frequent use. |
| Increased sun sensitivity | Uncommon | PHAs are generally less photosensitizing than AHAs, but sunscreen is still advised. |
| Allergic contact dermatitis | Rare | Hypersensitivity reactions are infrequently reported. |
| Mild stinging or tingling | Uncommon | More likely at higher concentrations or on sensitive or compromised skin. |
| Transient erythema (redness) | Uncommon | Usually temporary and resolves after discontinuation or lowering concentration. |
| Dryness or irritation | Uncommon | Can occur with frequent use or in combination with other actives. |
| Mild transient skin irritation or stinging | Uncommon | More likely on compromised or sensitive skin or at higher concentrations. |
| Redness or transient burning sensation | Rare | Typically self-limiting and resolves after discontinuation. |
| Mild skin irritation | Uncommon | Possible at higher concentrations, particularly on sensitive or compromised skin. |
| Enhanced irritation from co-formulated actives | Uncommon | By increasing penetration, it may intensify the effects or irritation potential of other ingredients. |
| Eye irritation | Rare | Can occur with accidental contact in concentrated form. |
| Mild transient stinging or irritation | Uncommon | More likely on compromised or sensitive skin, especially at higher concentrations. |
| Skin dryness or tightness | Rare | Possible with high concentrations in leave-on products. |
| Redness or erythema | Uncommon | Typically mild and resolves after discontinuation. |
Frequencies reflect typical cosmetic use reported in the literature, not a guarantee for your skin.
| Ingredient | What it does |
|---|---|
| gluconolactone Key active Polyhydroxy acid (PHA) exfoliant/humectant | Gluconolactone is a polyhydroxy acid that gently exfoliates the skin surface, provides antioxidant and humectant benefits, and is often considered milder than alpha hydroxy acids. It is well tolerated, including by sensitive skin, due to its larger molecular size and slower penetration. |
| 3-O-Ethyl Ascorbic Acid Key active Antioxidant / brightening vitamin C derivative | 3-O-Ethyl Ascorbic Acid is a stable, water-soluble ethylated derivative of vitamin C that converts to ascorbic acid in the skin, providing antioxidant protection and supporting collagen synthesis and pigmentation control. It is valued for greater stability than pure L-ascorbic acid while delivering similar brightening and anti-aging benefits. |
| 3-Propanediol Humectant / solvent | 1,3-Propanediol is a naturally-derived glycol used in skincare as a humectant, solvent, and texture enhancer that helps boost skin hydration and improve the spreadability and stability of formulations. It is often produced via fermentation of corn sugar as a plant-based alternative to propylene glycol. |
| Ethoxydiglycol Solvent / penetration enhancer | Ethoxydiglycol (diethylene glycol monoethyl ether) is a glycol ether used in cosmetic formulations primarily as a solvent and viscosity reducer that helps dissolve active ingredients and improve their skin penetration. It is considered a formulation aid rather than a therapeutic active. |
| Pentylene Glycol Humectant / solvent / preservative-booster | Pentylene glycol is a glycol used in cosmetics as a humectant and solvent that also enhances the antimicrobial efficacy of formulations, helping reduce reliance on traditional preservatives. It improves skin hydration and aids the delivery and stability of other ingredients. |
| Methylpropanediol Humectant/solvent | Methylpropanediol is a small glycol-type ingredient used in skincare as a humectant and solvent that helps hydrate skin and enhance the penetration of other actives. It also contributes to product texture and can support preservative efficacy. |
| Glycerin Humectant | Glycerin is a widely used humectant that attracts and retains water in the skin, helping to hydrate the stratum corneum and support barrier function. It is considered safe and well-tolerated across most skin types and concentrations. |
| Dimethyl Isosorbide Solvent / penetration enhancer | Dimethyl Isosorbide (DMI) is a small, polar solvent derived from isosorbide used in cosmetic formulations to dissolve active ingredients and enhance their penetration into the skin. It functions as a vehicle and carrier rather than a therapeutic active itself. |
| Houttuynia Cordata (Heart Leaf) Extract Key active Soothing antioxidant | Houttuynia Cordata extract is a botanical ingredient rich in flavonoids and polyphenols, used in skincare for its antioxidant, anti-inflammatory, and soothing properties. It is often included in formulations targeting sensitive, acne-prone, or irritated skin. |
| Sodium Hyaluronate Humectant / hydrator | Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan that attracts and binds water to the skin to improve hydration and surface plumpness. Its lower molecular weight allows better penetration than native hyaluronic acid. |
| L-Ascorbic Acid Key active Antioxidant / brightening active | L-Ascorbic Acid is the biologically active form of vitamin C used topically as a potent antioxidant that helps neutralize free radicals, supports collagen synthesis, and can reduce hyperpigmentation. Its efficacy depends on low pH (typically below 3.5) and stable formulation, as it readily oxidizes when exposed to light, air, and heat. |
| Ferulic Acid Key active Antioxidant | Ferulic acid is a plant-derived phenolic antioxidant that neutralizes free radicals and helps protect skin from UV-induced oxidative damage. It is frequently combined with vitamins C and E to enhance their stability and photoprotective effect. |
| Gluconolactone Key active Polyhydroxy acid (PHA) exfoliant/humectant | Gluconolactone is a polyhydroxy acid that gently exfoliates the skin surface, provides antioxidant and humectant benefits, and is often considered milder than alpha hydroxy acids. It is well tolerated, including by sensitive skin, due to its larger molecular size and slower penetration. |
| 2-Hexanediol Humectant/preservative-booster | 1,2-Hexanediol (commonly written 2-hexanediol) is a multifunctional diol used in skincare primarily as a humectant, solvent, and preservative-enhancing agent that improves the antimicrobial efficacy of formulations. It is generally well tolerated and considered a base/formulation ingredient rather than a treatment active. |
| Laminaria Digitata Extract Conditioning/antioxidant | Laminaria Digitata Extract is derived from brown seaweed and is used in skincare for its mineral, polysaccharide, and antioxidant content, providing skin-conditioning, hydrating, and soothing benefits. It is commonly included for its purported moisturizing and protective properties. |
| Hydrogenated Lecithin Emollient / Emulsifier | Hydrogenated lecithin is a phospholipid derived from lecithin through hydrogenation, used in skincare as an emulsifier, emollient, and skin-conditioning agent. It also helps stabilize formulations and form liposomes that can aid delivery of other ingredients. |
| Cetyl-Pg Hydroxyethyl Palmitamide Skin-conditioning emollient / pseudo-ceramide | Cetyl-PG Hydroxyethyl Palmitamide is a synthetic pseudo-ceramide used to mimic natural skin ceramides, helping to support the skin barrier and reduce transepidermal water loss. It functions as an emollient and moisturizing agent commonly found in barrier-repair and dry-skin formulations. |
| Sclerotium Gum Thickener / stabilizer | Sclerotium Gum is a natural polysaccharide produced by fermentation of the fungus Sclerotium rolfsii, used as a thickening, gelling, and emulsion-stabilizing agent in cosmetic formulations. It also imparts a smooth skin feel and helps suspend particles in creams, gels, and serums. |
| Ceramide Eop Skin barrier lipid | Ceramide EOP is a long-chain omega-hydroxy ceramide that helps form and maintain the skin's lipid barrier, supporting moisture retention and reducing transepidermal water loss. It is commonly used in moisturizers and barrier-repair formulations. |
| Ceramide Ns/Ceramide Ng Skin-barrier lipid / moisturizer | Ceramide NS (Ceramide 2/NG) is a naturally occurring sphingolipid that helps form and maintain the skin's lipid barrier, reducing transepidermal water loss and improving hydration. It is widely used in moisturizers and barrier-repair formulations. |
| Ceramide Np Skin-barrier replenishing lipid / emollient | Ceramide NP (formerly ceramide 3) is a naturally occurring sphingolipid that helps restore and maintain the skin's lipid barrier, reducing transepidermal water loss and improving hydration. It is widely used in moisturizers and barrier-repair formulations. |
| Ceramide As Skin-barrier lipid / emollient | Ceramide AS is a synthetic sphingolipid that mimics naturally occurring skin ceramides, helping restore and reinforce the stratum corneum barrier and reduce transepidermal water loss. It is commonly used in moisturizers and barrier-repair formulations. |
| Ceramide Ap Skin barrier lipid / moisturizer | Ceramide AP (ceramide 6-II) is a naturally occurring sphingolipid that helps restore and maintain the skin's barrier function and reduce transepidermal water loss. It is commonly used in moisturizers and barrier-repair formulations, often combined with other ceramides, cholesterol, and fatty acids. |
| Sodium Phytate Chelating agent | Sodium Phytate is the sodium salt of phytic acid used in cosmetic formulations primarily as a chelating agent to bind metal ions, improving product stability and preventing oxidation. It can also offer mild antioxidant support and is often included at low concentrations. |
| Sodium Starch Octenylsuccinate Absorbent / texturizing agent | Sodium starch octenylsuccinate is a modified starch derived from corn or other plant sources, used in skincare and cosmetics as an oil-absorbing, mattifying, and texture-enhancing ingredient. It helps create a soft, dry, powdery feel and can stabilize emulsions. |
| Calcium Gluconate Buffering/skin-conditioning agent | Calcium gluconate is a calcium salt of gluconic acid used in topical formulations as a source of calcium, a buffering agent, and a skin-conditioning ingredient. It is also notably used medically as an antidote gel for hydrofluoric acid burns. |
| Tris(Tetramethylhydroxypiperidinol) Citrate Antioxidant / chelating stabilizer | Tris(Tetramethylhydroxypiperidinol) Citrate is a hindered amine (HALS-type) antioxidant and metal-chelating agent used in skincare to protect formulations from oxidative degradation and to help neutralize free radicals. It functions primarily as a stabilizer and secondary antioxidant rather than a primary treatment active. |
| Citric Acid pH adjuster / AHA exfoliant | Citric acid is an alpha-hydroxy acid derived from citrus fruits, used primarily to adjust and buffer formulation pH and as a chelating agent, and at higher concentrations as a mild chemical exfoliant. It can promote surface cell turnover and is sometimes included in antioxidant or brightening products. |
| Phenoxyethanol Preservative | Phenoxyethanol is a widely used broad-spectrum preservative that protects cosmetic and skincare formulations from bacterial and fungal contamination. It is typically used at concentrations up to 1% and serves as a formulation/base ingredient rather than an active treatment. |
| Hydrated Silica Abrasive/absorbent | Hydrated silica is a porous form of silicon dioxide used in skincare and toothpaste as a mild abrasive, absorbent, and viscosity-controlling agent. It helps with gentle exfoliation, oil absorption, and texture improvement in formulations. |
| Sodium Benzoate Preservative | Sodium benzoate is a salt of benzoic acid used as a preservative in cosmetic and skincare formulations to inhibit the growth of bacteria, yeast, and fungi, particularly in acidic products. It is most effective at a pH below 5. |
| Sodium Metabisulphite Antioxidant/preservative | Sodium metabisulphite is an inorganic sulfite salt used in cosmetic and pharmaceutical formulations primarily as an antioxidant and preservative to prevent oxidation and discoloration of sensitive ingredients. It is typically present at low concentrations as a formulation stabilizer rather than as a therapeutic active. |
Key active = does the main work. Ingredient explanations are drawn from public databases & literature.
Peer-reviewed papers on the active ingredients in this product, via PubMed.